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2000 articles

November 202624

Clinical ResearchRheumatology

Validity of the 2023 ACR/EULAR APS classification criteria for paediatric primary APS: inputs from a systematic literature review.

This systematic literature review and individual participant data-style random-effects meta-analysis assessed the 2023 ACR/EULAR antiphospholipid syndrome (APS) classification criteria in children with primary APS.

Rheumatology (Oxford)Nov 4, 2026Read summary
Clinical ResearchNephrology

Effect of Kunxian capsule, a novel Tripterygium wilfordii preparation, on reducing proteinuria and slowing renal function decline in diabetic kidney disease: a 48-week randomized controlled trial.

This 48-week randomized controlled trial assigned 80 patients with diabetic kidney disease to irbesartan-based standard therapy with or without adjunctive Kunxian capsule.

Ren FailNov 4, 2026Read summary
Clinical ResearchPsychiatry

Enhancing Empathic Functioning in Married Individuals Experiencing Marital Conflict Through Mentalization-Based Therapy in Iran.

This randomized controlled study examined whether Mentalization-Based Therapy (MBT) changed self-reported empathy among 30 married individuals experiencing marital conflict in Iran.

J Marital Fam TherNov 4, 2026Read summary
Case ReportGeneral Surgery

Enhancing Peri-implant Papillae: A Minimally Invasive Approach with Integrated Prosthetic Solutions.

This case series describes four patients with deficient interproximal papillae and soft-tissue contours around implants. The cases included adjacent implants treated with soft-tissue grafting at stage-two surgery or…

Int J Periodontics Restorative DentNov 4, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Histologic Evaluation of Bone Regeneration Using the Subperiosteal Peri-implant Augmented Layer (SPAL) Technique Combined with Deproteinized Bovine Bone Mineral: A Case Report.

Six patients with peri-implant bone dehiscence underwent augmentation using the subperiosteal peri-implant augmented layer (SPAL) technique with particulate deproteinized bovine bone mineral.

Int J Periodontics Restorative DentNov 4, 2026Read case
Case ReportPlastic Surgery

Reconstruction of the Burned Nose Using an Expanded Skin-Grafted Forehead Flap, Delayed Turnover Flaps, and Indocyanine Green Perfusion Assessment.

A 35-year-old man developed severe nasal deformity and airway compromise after a flame burn involving about 20% of total body surface area.

J Burn Care ResNov 4, 2026Read case
Clinical ResearchNeurologyOpen access

Immune checkpoints inhibitors in the treatment of progressive multifocal leukoencephalopathy: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed immune checkpoint inhibitors (ICIs) for progressive multifocal leukoencephalopathy (PML), pooling reports involving 186 patients from 52 articles.

Neurol SciNov 4, 2026Read summary
Clinical ResearchCardiology

A randomized comparison of comprehensive weight loss intervention vs. usual care on recurrences of atrial fibrillation in obese patients after catheter ablation: HOBIT-AF trial.

The HOBIT-AF randomized controlled trial tested whether a comprehensive weight-loss intervention reduced atrial fibrillation or atrial tachycardia (AF/AT) recurrence after catheter ablation in obese patients.

EuropaceNov 4, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

Coexistence of ARNT::ALK and TPM3::ALK doublegene fusion in an ALK-rearranged renal cell carcinoma with osseous metaplasia.

An adult patient had an ALK-rearranged renal cell carcinoma. The tumor showed varied growth patterns in a mucinous background, with a small peripheral focus of osseous metaplasia.

Am J Clin PatholNov 4, 2026Read case
Clinical ResearchNephrologyOpen access

Proton pump inhibitors in prevention of cisplatin-induced nephrotoxicity: a systematic review.

This systematic review assessed whether proton pump inhibitor (PPI) co-administration prevents cisplatin-related kidney injury and whether it is safe.

Support Care CancerNov 4, 2026Read summary
Clinical ResearchPulmonology

Systemic corticosteroids in critical illness: an evidence-based framework for clinical decision-making.

This systematic review qualitatively synthesized randomized trials, reviews, and meta-analyses to develop a decision framework for systemic corticosteroids in severe community-acquired pneumonia (sCAP), acute…

Eur J Clin PharmacolNov 4, 2026Read summary
Case ReportInternal Medicine (General)Open access

Pseudo-Metabolic Alkalosis: A Hidden Laboratory Pitfall With Elevated LDH.

A 33-year-old man presented with progressive exertional dyspnea, syncope, and paresthesia. Testing showed pancytopenia, macrocytosis, LDH >3600 U/L, low haptoglobin, and vitamin B₁₂ <68 pg/mL, consistent with pernicious…

Yale J Biol MedNov 4, 2026Read case
Case ReportNeurologyOpen access

Late-onset Niemann-Pick C disease in a patient with spastic ataxia and hyperkinetic involuntary movements: a case report.

A woman with late-onset Niemann-Pick disease type C1 presented from age 50 with progressive postural instability, falls, spastic ataxia, and prominent upper-limb hyperkinetic movements.

Mol Biol RepNov 4, 2026Read case
Case ReportNeurologyOpen access

Spinocerebellar Ataxia Type 6 Concurrent with Normal-Pressure Hydrocephalus: A Case Report.

A 73-year-old man with two years of progressive gait disturbance had gaze-evoked nystagmus, dysarthria, limb ataxia, a broad-based shuffling gait, and urinary urgency.

CerebellumNov 4, 2026Read case
Clinical ResearchOncology (Medical)Open access

Effects of digital stress-management interventions in breast cancer patients 18 months after intervention access.

This randomized controlled trial examined whether app-based cognitive behavioral (CBI) or mindfulness-based (MBI) stress management was associated with improved outcomes 18 months after access began among patients with…

Breast Cancer Res TreatNov 4, 2026Read summary
Case ReportVascular Surgery

Angiosarcoma in the Setting of Vascular Procedures: A Systematic Review and Our Experiences.

Angiosarcoma is a rare, aggressive endothelial malignancy with a poor prognosis; diagnosis is often delayed by vague symptoms, nonspecific imaging, and challenging histopathology.

Interdiscip Cardiovasc Thorac SurgNov 3, 2026Read case
Case ReportObstetrics & GynecologyOpen access

Rare Sites of Metastases to the Breast and Integumentary System in Advanced Cervical Cancer at Initial Presentation in Eastern Uganda: A Case Report.

A 72-year-old woman in Uganda presented after 13 months of intermittent postmenopausal bleeding and abnormal vaginal discharge, despite repeated treatment for presumed urinary and sexually transmitted infections.

Int Med Case Rep JNov 3, 2026Read case
Clinical ResearchNephrology

Risk factors for cognitive impairment in patients undergoing hemodialysis: an umbrella review and meta-analysis.

This umbrella review and meta-analysis examined factors associated with cognitive impairment and cognitive frailty in adults receiving maintenance hemodialysis. It included five meta-analyses covering 97 associations.

Ren FailNov 3, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Barriers to Gender-Affirming Care for Nonbinary People: A Systematic-Narrative Hybrid Literature Review.

This systematic-narrative hybrid literature review synthesised qualitative, quantitative and mixed-methods research, alongside systematic and scoping reviews, on barriers to gender-affirming care for nonbinary people.

Health Promot J AustrNov 3, 2026Read summary
Case ReportCardiothoracic Surgery

Concomitant Robotic Pericardial Window and Mediastinal Tumour Biopsy Under Intraoperative Ultrasound Guidance.

An 83-year-old woman presented with an undiagnosed mediastinal mass and a symptomatic, loculated pericardial effusion. She underwent a robotic pericardial window and mediastinal tumour biopsy performed together under…

Interdiscip Cardiovasc Thorac SurgNov 3, 2026Read case
Case ReportInfectious Diseases

Metagenomic Next-Generation Sequencing of Mycoplasma hominis Infection in an Immunocompromised Patient: A Case Report.

A 52-year-old immunocompromised man developed persistent soft-tissue infection after a wooden splinter injury, with recurrent fever, wound pain, swelling, and exudation.

J Vis ExpNov 3, 2026Read case
Case ReportMedical GeneticsOpen access

KARS1-Related Infantile-Onset Progressive Leukoencephalopathy With or Without Deafness: A Novel Variant and Phenotypic Expansion.

A two-year-old Iranian boy born to non-consanguineous parents presented with developmental delay, seizures, and sensorineural hearing loss.

J Mol NeurosciNov 3, 2026Read case
Clinical ResearchCardiothoracic Surgery

Multivessel Versus Single-Vessel Coronary Endarterectomy as an Adjunct to Coronary Artery Bypass Grafting: A Meta-Analysis of Short-Term Outcomes and Implications for Target-Vessel Selection.

This meta-analysis compared short-term outcomes after single-vessel versus multivessel coronary endarterectomy (CE) performed with coronary artery bypass grafting (CABG), using studies that reported both groups within…

Interdiscip Cardiovasc Thorac SurgNov 3, 2026Read summary
Case ReportInfectious Diseases

Short communication: Urinary schistosomiasis mimicking a bladder tumour in a Somali student diagnosed in Türkiye.

A 20-year-old Somali student living in Türkiye presented with painless visible haematuria and lower urinary tract symptoms. He had a history of freshwater exposure in Somalia.

J HelmintholNov 3, 2026Read case

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