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2000 articles
October 202624
A Consistently Elevated Pineal Gland Uptake of 18 F-MFBG as a Physiological Normal Variant.
A 3-year-old girl with high-risk neuroblastoma underwent 18F-MFBG PET/CT to assess treatment response. Imaging showed focal pineal gland uptake, also present on concurrent 68Ga-DOTATATE PET/CT.
Optimizing exercise prescriptions for older adults with mild cognitive impairment: a dose-response network meta-analysis of modality-dose combinations on executive function.
This Bayesian dose-response network meta-analysis synthesized randomized controlled trials of repeated exercise programmes in adults aged 60 years or older with mild cognitive impairment.
Combination of oral fluoropyrimidines and EGFR-directed antibodies in frail patients with metastatic colorectal cancer: a systematic review.
This systematic review assessed phase II and III evidence for oral fluoropyrimidines combined with EGFR-directed antibodies in patients with RAS wild-type metastatic colorectal cancer, including those considered unfit…
Not Every PSMA-Expressing Bone Lesion Is Prostate Cancer: Incidental Detection of Metastatic Differentiated Thyroid Carcinoma on Staging 68 Ga-PSMA-11 PET/CT.
A patient with newly diagnosed high-risk prostate adenocarcinoma underwent staging 68Ga-PSMA-11 PET/CT. Alongside the primary prostatic lesion, PSMA-expressing foci were seen in the sternum and right thyroid lobe.
Initial HIV Therapy for Adults and Treatment-Associated Weight Gain: The Opti-DOR Randomized Clinical Trial.
The Opti-DOR open-label, noninferiority randomized trial compared two initial antiretroviral regimens in 600 ART-naive adults at two South African sites; 99.5% of participants were Black African.
Meta-analysis of 990 EBV genomes identifies EBER2 SNP7048 and its interaction with HLA-A*11:01 driving nasopharyngeal carcinoma risk.
This meta-analysis examined whether EBV genetic variation and host genetics are associated with nasopharyngeal carcinoma (NPC) across endemic populations in Singapore, Hong Kong, and China’s Guangdong and Guangxi…
A Favorable Partial Response in Patients With Glioblastoma Multiforme Following Combined [ 177 Lu]Lu-FAP-2286 and Chemotherapy.
A 64-year-old woman with IDH-wild-type, WHO grade IV glioblastoma underwent [68Ga]Ga-FAP-2286 PET/CT, which detected active tumor recurrence before definitive radiologic evidence of progression.
FDG PET/CT Unmasking Acute Rheumatic Fever Presenting as Polyenthesitis.
A 13-year-old boy was evaluated with FDG PET/CT for fever of unknown origin. Imaging showed extensive abnormal activity around joints in all four extremities and probable myopericarditis.
A Tale of 3 Tracers: Contrasting Uptake Patterns of 18 F-FDG, 68 Ga-DOTATATE, and 18 F-MFBG in a Pediatric Neuroblastoma Patient.
A 5-year-old boy underwent 18 F-FDG PET/CT before neuroblastoma was confirmed histologically. Imaging showed a metabolically active left adrenal primary tumor and liver metastases.
Intradiverticular Bladder Cancer Mimicking a Normal Urinary Bladder Diverticulum on FDG PET/CT.
A patient with a bladder diverticulum underwent FDG PET/CT for evaluation of intradiverticular bladder cancer. On imaging at 62 minutes, the exophytic lesion had a density similar to bladder urine and intense FDG…
Unusual Isolated Thymic Relapse of Neuroblastoma Detected By 123 I-mIBG Scintigraphy in a Pediatric Patient.
A pediatric patient with neuroblastoma developed an anterior mediastinal mass representing thymic relapse. The mass showed intense uptake on 123I-meta-iodobenzylguanidine (123I-mIBG) scintigraphy, which detected the…
Oxygen vs Air at Birth for Moderate- to Late-Preterm Infants: The AIROPLANE Cluster Randomized Crossover Trial.
The AIROPLANE trial was an unblinded, cluster randomized crossover study at 26 Australian maternity hospitals comparing initial oxygen concentrations of 0.30 and 0.21 during the first 3 minutes of respiratory support…
Cochlear Implantation in a Child With Arnold-Chiari Syndrome, Severe Inner Ear Malformations, and Cochlear Nerve Hypoplasia: A Case Report.
A 1.5-year-old girl with Arnold-Chiari malformation, hydrocephalus, spina bifida, and profound bilateral sensorineural hearing loss had limited auditory development despite early hearing-aid use.
FDG PET/CT in IgG4-related Disease Involving the Urethra.
A woman with IgG4-related disease presented with obstructive urinary symptoms. FDG PET/CT and delayed pelvic PET/MRI demonstrated marked circumferential urethral wall thickening with intense diffuse FDG uptake (SUV max…
The Clinical Significance of Hyperkinetic Biliary Dyskinesia on HIDA Scan: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed outcomes after cholecystectomy in patients with biliary-type pain and gallbladder ejection fraction (EF) ≥80% on CCK-stimulated HIDA scans.
Entinostat plus exemestane for hormone receptor-positive advanced breast cancer: long-term overall survival results from the EOC103A3101 randomized controlled trial.
This randomized controlled trial assessed long-term overall survival with entinostat plus exemestane versus placebo plus exemestane in 354 patients with hormone receptor-positive, HER2-negative advanced breast cancer…
Interventions Supporting Functional Recovery After Traumatic Brain Injury in Public Safety Personnel: A Systematic Review of Outcomes and Work Reintegration Considerations.
This systematic review synthesized evidence on interventions for functional recovery and return to work (RTW) among public safety personnel (PSP) with traumatic brain injury.
Primary intracranial sarcoma, DICER1-mutant: 5 cases highlighting variable clinical and molecular features.
The report describes five patients aged 6 to 40 years with primary intracranial sarcoma, DICER1-mutant, identified through methylation profiling and/or sequencing.
Extraosseous 99m Tc Methylene Diphosphonate Uptake in Perianal Dystrophic Calcification : Incremental Value of Single-photon Emission CT/CT.
A 57-year-old woman underwent three-phase 99mTc methylene diphosphonate bone scintigraphy for persistent right hip pain following femoral neck fracture fixation.
Chondromyxoid Fibroma of the Rib on 99m Tc-MDP SPECT/CT.
A 37-year-old woman with persistent right-sided back pain underwent ⁹⁹ᵐTc-MDP SPECT/CT, which showed a solitary focus of intense radiotracer uptake corresponding to a rib lesion.
Effectiveness and safety of adjunct interventions for external cephalic version in breech presentation: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed adjunct and procedural strategies for external cephalic version (ECV) in pregnant women with breech presentation, drawing on 10 randomised controlled trials with 2,745…
Challenges of Conducting a Feasibility Pilot Randomized Controlled Trial During COVID-19 Restrictions: Rivaroxaban Versus Acetyl Salicylic Acid in Patients with Multiple Myeloma on Lenalidomide-Based Therapy (RithMM).
This multicentre pilot randomised controlled trial assessed whether a full-scale comparison of rivaroxaban and acetylsalicylic acid for thromboprophylaxis was feasible in patients with multiple myeloma receiving…
The effect of seizure-free period on seizure recurrence following antiseizure medication withdrawal: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined whether the duration of seizure freedom before antiseizure medication (ASM) withdrawal is associated with subsequent seizure recurrence in people with…
Neonatal gastric perforation: a systematic review and meta-analysis of clinical characteristics, risk factors, surgical management and outcomes.
This systematic review and meta-analysis examined clinical features, risk factors, surgical management and outcomes of neonatal gastric perforation using observational studies of neonates aged 28 days or younger.
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