Unusual Isolated Thymic Relapse of Neuroblastoma Detected By 123 I-mIBG Scintigraphy in a Pediatric Patient.

Clin Nucl MedOct 20, 2026 (epub)
Case ReportPediatricsOncology (Medical)Nuclear Medicine

Kailash Chaurasiya, Elena Kireeva, Maxim Dunaikin et al.

✦ AI-curated · Sources linked

Case in brief

A pediatric patient with neuroblastoma developed an anterior mediastinal mass representing thymic relapse. The mass showed intense uptake on 123I-meta-iodobenzylguanidine (123I-mIBG) scintigraphy, which detected the recurrence. The report describes an isolated thymic site of relapse, an unusual location compared with the more frequent metastatic sites of bone marrow, bone, lymph nodes, and liver. The abstract does not provide further clinical findings, confirmatory testing, or details of treatment or outcome.

What made this case unusual

The relapse was isolated to the thymus, presenting as an anterior mediastinal mass—an uncommon soft-tissue recurrence site for neuroblastoma.

Diagnostic / clinical pearl

In a patient with neuroblastoma, intense 123I-mIBG uptake in an anterior mediastinal mass can identify thymic relapse, despite its unusual location.

Source

PubMed · PMID 42912580

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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