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2000 articles
October 202624
Integrated management of uterine prolapse during pregnancy: Case report and literature review of successful term delivery following cervical cerclage and pessary utilization.
A 43-year-old woman with recurrent pregnancy losses, including a second-trimester loss attributed to cervical incompetence, presented at 11 weeks’ gestation with stage III uterine prolapse.
Clinical Reasoning: A 60-Year-Old Woman With Progressive Dysarthric Speech and Gait Instability.
A 60-year-old woman developed progressive dysarthria and gait instability over 2 months, with chronic constipation and substantial weight loss.
Maternal and Fetal Safety Outcomes of Thrombolytics for Ischemic Stroke in Pregnancy: A Systematic Review and Aggregated Case Series.
This systematic review and Bayesian aggregated case series examined maternal and fetal outcomes after thrombolytic treatment during pregnancy.
The effect of early rehabilitation nursing on the recovery of cardiac function in patients with acute myocardial infarction.
This prospective randomised controlled trial compared structured early rehabilitation nursing with routine postoperative nursing in patients with acute myocardial infarction treated by percutaneous coronary…
Heterogeneity in Depression and Suicidality Risk Among Vitiligo Patients: A Meta-Analysis of Adolescent Complexity and Subgroup Stratification.
This meta-analysis assessed depression and suicidality in people with vitiligo, drawing on 73 studies identified through searches of four databases. The pooled prevalence of depression was 0.37 (95% CI, 0.30-0.45).
Prenatal Microarray Incidentally Diagnoses a Novel Inherited NF1 Intragenic Duplication.
A woman with an undisclosed clinical diagnosis of NF1, lost to follow-up as a teenager, received a molecular diagnosis after prenatal chromosome microarray was performed because first-trimester screening indicated a…
Reducing Central Line-Associated Bloodstream Infections in ICUs: A Systematic Review of Barriers and Facilitators and Intervention Measures.
This PRISMA-guided systematic review examined barriers and facilitators to implementing central line-associated bloodstream infection (CLABSI) prevention among ICU healthcare workers.
The Effects of Virtual Reality Group Reminiscence Therapy on Agitation, Cognition, Depression and Social Function in Patients With Alzheimer's Disease.
This assessor-blinded randomised controlled trial evaluated multisensory virtual reality group reminiscence therapy in 60 people with Alzheimer’s disease, comparing twice-weekly 40-minute sessions for 8 weeks with…
Decitabine plus busulfan-cyclophosphamide versus busulfan-cyclophosphamide myeloablative conditioning before allogeneic haematopoietic stem cell transplantation for reducing risk of relapse in adult KMT2A‑rearranged leukaemia in China: an open-label, multicentre, randomised phase 3 trial.
This open-label, multicentre, randomised phase 3 trial compared decitabine plus busulfan-cyclophosphamide (DAC-BuCy) with BuCy conditioning before allogeneic HSCT in 130 patients aged 14–65 years with KMT2A-rearranged…
The Effect of Bupropion in Peripheral Neuropathic Pain A Randomized, Double-Blind, Placebo-Controlled Study.
This randomized, double-blind, placebo-controlled crossover study assessed bupropion for peripheral neuropathic pain and whether response varied with conditioned pain modulation (CPM) or sensory phenotype.
Effectiveness of Tomazoni Measurement Method for Central Catheter Tip Positioning in Neonates: A Randomised Controlled Trial.
This pragmatic, parallel-group randomised controlled trial compared the Tomazoni and traditional measurement methods for positioning peripherally inserted central catheter (PICC) tips in neonates at a Brazilian neonatal…
Metabolic, hormonal, and reproductive effects of GLP-1 receptor agonizts in hyperandrogenic insulin-resistant women: a systematic review.
This systematic review evaluated GLP-1 receptor agonists for metabolic, hormonal, and reproductive outcomes in adult women with hyperandrogenic insulin-resistant conditions, principally polycystic ovary syndrome and…
Phase 1 Study of Safety and PK With A Combination of Omeprazole and Trimetazidine for Fatty Acid Oxidation Inhibition in Patients With Advanced Solid Tumors.
This Phase I, open-label, 3 + 3 dose-escalation study assessed safety, tolerability, pharmacokinetics, and preliminary antitumor activity of once-daily oral omeprazole plus trimetazidine, two fatty acid oxidation…
The Effects of Force-Velocity Profile-Based Load Prescription on Muscle Power and Functional Performance in Velocity-Deficient Older Adults.
This 12-week randomized controlled trial compared force–velocity profile-guided resistance-training loads in adults aged 65 years or older with a velocity deficit.
Effects of a music-accompanied multimodal exercise program on trunk endurance, stress, and anxiety in university students: a randomized controlled trial.
This randomized controlled trial evaluated a 12-week, music-accompanied program combining core stabilization, diaphragmatic breathing, and relaxation in 80 university students assigned to intervention or waitlist…
Conservative management of disseminated intravascular coagulation caused by uterine leiomyoma degeneration in pregnancy: Case report and review.
A 35-year-old woman at 25 weeks’ gestation presented with lower abdominal pain and a tender 6.5 cm uterine leiomyoma; fetal well-being and placental appearance were normal on ultrasonography.
Treatment Procedures for the Edentulous Maxilla: Supplement Report for the First Global Consensus for Clinical Guidelines (GCCG).
The report describes clinical rehabilitation of an edentulous maxilla using implant-supported restorations. It applies the treatment-procedures component of the First Global Consensus for Clinical Guidelines (GCCG)…
Treatment of Refractory Descemet Membrane Detachment via Repeat Descemetopexy: A Case Report.
An 82-year-old man with age-related cataract and a history of bilateral pterygium surgery with corneal scarring developed Descemet membrane detachment during phacoemulsification and intraocular lens implantation.
Double heterozygous pathogenic germline APC and MSH2 variants in a 16-year-old female diagnosed with colorectal cancer.
A 16-year-old female presented with multiple colonic polyps and invasive colorectal carcinoma. Genetic testing identified heterozygous pathogenic variants in both APC and MSH2, consistent with the genetic basis of…
BCMA-directed CAR T-cell therapy induces durable drug-free remission in refractory primary immune thrombocytopenia.
This phase I clinical trial evaluated B-cell maturation antigen (BCMA)-directed chimeric antigen receptor T-cell therapy in 4 patients with refractory primary immune thrombocytopenia.
Prevalence of depression and anxiety among patients with Behçet's disease: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis estimated depression and anxiety prevalence among patients with Behçet’s disease (BD).
A Systematic Review and Meta-Analysis of Randomized Clinical Trials Comparing the Effectiveness of Corticosteroid Injection Versus Night Splints in Patients With Carpal Tunnel Syndrome.
This systematic review and meta-analysis of randomized controlled trials compared corticosteroid injection (CSI) with night splinting (NS) for carpal tunnel syndrome.
Ectopic cushing syndrome caused by intestinal neuroendocrine tumors: a systematic review.
This systematic review characterized ectopic Cushing syndrome caused by intestinal neuroendocrine tumors using published case reports and an illustrative unpublished case. It identified 24 published cases.
A pilot study of electromagnetic therapy versus biofeedback-based pelvic floor muscle training for pelvic organ prolapse: A mixed-methods approach.
This mixed-methods pilot randomised trial compared high-intensity focused electromagnetic (HIFEM) therapy, supervised pelvic floor muscle training (PFMT) with biofeedback and/or electrostimulation, and usual care in…
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