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2000 articles

November 202624

Case ReportRadiology (Diagnostic)

Imaging and Clinical Features of Secondary Spinal Cord Lymphoma: A 2-Center Case Series.

This two-center case series describes 18 cases of secondary spinal cord lymphoma. The authors examined spinal MRI findings and their relationship to intracranial disease, systemic lymphoma, and clinical features.

AJNR Am J NeuroradiolNov 3, 2026Read case
Clinical ResearchGastroenterologyOpen access

Colonoscopy surveillance after colorectal cancer surgery: meta-analysis.

This systematic review and meta-analysis examined randomized trials comparing follow-up protocols with versus without colonoscopy within 5 years after colorectal cancer surgery.

BJS OpenNov 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Coronary artery calcification is not associated with survival in advanced gastric and gastroesophageal junction cancer: a secondary analysis of the EXPAND trial.

This secondary analysis of baseline CT images from the phase III EXPAND trial assessed whether coronary artery calcification (CAC) predicted overall survival in 785 patients with unresectable locally advanced or…

J Cancer Res Clin OncolNov 3, 2026Read summary
Clinical ResearchPulmonology

Transbronchial Cryobiopsy for the Diagnosis of Peripheral Pulmonary Lesions: A Prospective Randomized Controlled Study.

This prospective, single-center randomized controlled study compared radial endobronchial ultrasound with guide-sheath-assisted transbronchial cryobiopsy (TBCB) using a 1.1-mm ultrathin probe with conventional forceps…

J Vis ExpNov 3, 2026Read summary
Case ReportNeurologyOpen access

Homozygous SCA8 presenting as severe axonal neuropathy without overt cerebellar involvement.

A 35-year-old man with progressive limb weakness beginning at age 15 had severe proximal muscle atrophy and absent deep tendon reflexes, without overt cerebellar signs.

Neurol SciNov 3, 2026Read case
Clinical ResearchOncology (Medical)Open access

Oncologic efficacy and safety of stereotactic body radiotherapy for oligometastatic non-small cell lung cancer: a systemic meta-analysis.

This systematic review and meta-analysis assessed the efficacy and safety of stereotactic body radiotherapy (SBRT) for oligometastatic non-small cell lung cancer, including analyses by oligometastatic subtype and…

Clin Exp MetastasisNov 3, 2026Read summary
Case ReportObstetrics & GynecologyOpen access

Rare Sites of Metastases to the Breast and Integumentary System in Advanced Cervical Cancer at Initial Presentation in Eastern Uganda: A Case Report.

A 72-year-old woman in Uganda presented after 13 months of intermittent postmenopausal bleeding and abnormal vaginal discharge, despite repeated treatment for presumed urinary and sexually transmitted infections.

Int Med Case Rep JNov 3, 2026Read case
Clinical ResearchUrologyOpen access

Artificial Urinary Sphincter in Women: A Systematic Review of Clinical Outcomes and Technological Evolutions.

This systematic review examined clinical outcomes, surgical approaches, quality of life, and device developments for artificial urinary sphincter (AUS) implantation in women with stress urinary incontinence related to…

Curr Urol RepNov 3, 2026Read summary
Clinical ResearchCardiologyOpen access

Digital Outreach to Improve Statin Refills in Patients With Low Statin Adherence: The ADHERE-ASCVD Randomized Clinical Trial.

The ADHERE-ASCVD pragmatic, health system-embedded randomized clinical trial tested adaptive digital outreach to prompt statin refills among adults with established ASCVD or high ASCVD risk and recent nonadherence.

JAMANov 3, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Effects of exercise interventions on leptin and ghrelin levels in middle-aged and older adults with overweight or obesity: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed randomized controlled trials of exercise interventions in middle-aged and older adults with overweight or obesity, examining changes in leptin and ghrelin.

PeerJNov 3, 2026Read summary
Clinical ResearchPsychiatry

Efficacy of Lumateperone 42 mg in Major Depressive Disorder: Subgroup Analysis of a Phase 3 Randomized, Placebo-Controlled Trial.

This post hoc subgroup analysis of a phase 3, randomized, double-blind, placebo-controlled trial assessed adjunctive lumateperone 42 mg in adults with major depressive disorder and inadequate response to antidepressant…

Prim Care Companion CNS DisordNov 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Sitagliptin, a repurposed diabetes drug, overcomes gemcitabine resistance in pancreatic cancer via ribonucleotide reductase inhibition: SITGEM-CARE phase 2 trial.

SITGEM-CARE was a single-center, phase 2 clinical trial evaluating sitagliptin with gemcitabine and nab-paclitaxel in 22 patients with locally advanced or metastatic pancreatic ductal adenocarcinoma.

Signal Transduct Target TherNov 3, 2026Read summary
Clinical ResearchNeurologyOpen access

Tenecteplase Before Thrombectomy at 4.5 to 24 Hours for Basilar Artery Occlusion: The ATTENTION LATE Randomized Clinical Trial.

This multicenter, open-label, blinded-endpoint randomized clinical trial compared intravenous tenecteplase before endovascular thrombectomy (EVT) with EVT alone in patients with moderate to severe basilar artery…

JAMANov 3, 2026Read summary
Case ReportNeurologyOpen access

Network-Based Deep Brain Stimulation Rescue After Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Essential Tremor: Two Targeting Strategies.

Two men developed recurrent essential tremor after MRgFUS thalamotomy. In the 71-year-old, DBS was placed along a Vim–posterior subthalamic area trajectory.

Tremor Other Hyperkinet Mov (N Y)Nov 3, 2026Read case
Clinical ResearchOncology (Medical)Open access

Adjuvant mFOLFOXIRI after curative-intent resection of oligometastatic colorectal cancer: phase II FANTASTIC trial.

The multicentre, non-randomized phase II FANTASTIC trial evaluated adjuvant modified FOLFOXIRI after complete metastasectomy for oligometastatic colorectal cancer and assessed circulating tumour DNA (ctDNA).

BJS OpenNov 3, 2026Read summary
Case ReportOncology (Medical)

Children of advanced cancer patients need better support: A case report.

This case study describes a parent with advanced cancer and minor children who needed support in discussing the diagnosis, preparing the children for the possibility of death, and addressing anticipatory grief.

Palliat Support CareNov 3, 2026Read case
Case ReportOncology (Medical)

Multidisciplinary Single Stage Surgical Management of Advanced Breast Carcinoma With Concomitant Left Atrial Myxoma.

A 58-year-old woman with locally advanced invasive mucinous breast carcinoma had a progressive fungating mass despite neoadjuvant chemotherapy and radiotherapy.

Interdiscip Cardiovasc Thorac SurgNov 3, 2026Read case
Case ReportMedical GeneticsOpen access

KARS1-Related Infantile-Onset Progressive Leukoencephalopathy With or Without Deafness: A Novel Variant and Phenotypic Expansion.

A two-year-old Iranian boy born to non-consanguineous parents presented with developmental delay, seizures, and sensorineural hearing loss.

J Mol NeurosciNov 3, 2026Read case
Case ReportDermatology

A Case of Facial Alternaria alternata Infection in an Immunocompetent Male with Albinism.

A 26-year-old immunocompetent man with albinism who worked in breeding presented with a two-month history of itchy facial rashes.

MycopathologiaNov 3, 2026Read case
Clinical ResearchNeurologyOpen access

Clinical, neuroimaging and electroencephalographic differences between pediatric and adult HaNDL: a systematic review and pooled individual patient analysis.

This PRISMA 2020-guided systematic review and pooled individual patient analysis compared clinical and ancillary findings in pediatric and adult patients with HaNDL, a self-limited headache syndrome with cerebrospinal…

Neurol SciNov 3, 2026Read summary
Case ReportOncology (Medical)Open access

Pediatric suprasellar primary CNS lymphoma with cavernous sinus invasion and ischemic stroke: a case report and systematic review.

A 12-year-old immunocompetent girl presented with high fever, severe headache, and diplopia, followed by rapid neurological deterioration.

Childs Nerv SystNov 3, 2026Read case
Clinical ResearchRadiology (Diagnostic)

Imaging Modalities to Visualize Deep Cerebral Perforating Arteries: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed imaging methods for visualizing deep cerebral perforating arteries in human studies.

AJNR Am J NeuroradiolNov 3, 2026Read summary
Clinical ResearchNeurosurgery

Predictive Accuracy and Procedural Benefits of Software-Enhanced Flow-Diverter Planning: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed whether software simulations improve flow-diverter (FD) planning and procedural outcomes for intracranial aneurysms compared with physician planning.

AJNR Am J NeuroradiolNov 3, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Benson relaxation technique for perioperative anxiety and depressive symptoms in patients undergoing brain tumor surgery: a clinical trial.

This randomized controlled trial evaluated supervised Benson relaxation technique (BRT) sessions for perioperative anxiety and depressive symptoms in patients undergoing brain tumor resection.

Support Care CancerNov 3, 2026Read summary

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