Imaging‑based models for predicting cerebrovascular complications of carotid stenosis.
Baobao Li, Xiangrong Du, Yuan Liu et al.
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In 30 seconds
This systematic review protocol aims to evaluate multivariable prognostic models using imaging biomarkers to predict cerebrovascular complications in adults with carotid stenosis. The focus is on assessing the models' predictive performance for ipsilateral ischaemic stroke and transient ischaemic attack, with metrics such as discrimination and calibration being compared across studies.
Key findings
- The review will summarize models' discrimination using C-statistic/AUC and calibration metrics.
- It will include studies considering retinal ischaemia as a qualifying event for symptomatic carotid stenosis.
- The review aims to explore predictive performance differences based on imaging modality and technical protocol.
Why it matters
Understanding the predictive performance of imaging-based models can enhance risk stratification for cerebrovascular complications in patients with carotid stenosis, potentially guiding clinical decision-making and management strategies.