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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchGastroenterology

European Guidelines on Multidisciplinary Management of Obstructed Defecation Syndrome-ESCP, UEG, ESGAR, EAGEN, ESGENA, ESNM and ESPCG.

United European Gastroenterol JNov 1, 2026

These European multidisciplinary practice guidelines address diagnosis and management of obstructed defecation syndrome (ODS).

Why it matters

ODS care involves diagnostic testing and treatment options across several disciplines. These guidelines provide a shared framework for coordinating assessment and sequencing care, while making clear that much of the…

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Also worth knowing

Clinical ResearchNeurosurgeryOpen access

Efficacy and safety of middle meningeal artery embolisation for chronic subdural haematoma: a systematic review and meta-analysis of randomised controlled trials.

This PRISMA-compliant systematic review and meta-analysis pooled randomised controlled trials comparing middle meningeal artery embolisation (MMAE)-based treatment with standard management in adults with radiologically…

Neurosurg RevNov 11, 2026Read summary
Clinical ResearchPulmonologyOpen access

Mucus Plugging Across Multiple Chronic Respiratory Diseases: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed mucus-plug prevalence, clinical characteristics and outcomes across chronic respiratory diseases, including asthma, COPD and cystic fibrosis.

LungNov 6, 2026Read summary
Clinical ResearchUrology

Too good to be true? AI performance in CT-based urinary stone detection and classification: EAU endourology systematic review and diagnostic accuracy meta-analysis.

This systematic review and diagnostic accuracy meta-analysis assessed AI for detecting and classifying urinary stones on CT.

World J UrolNov 5, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Added Value of Preoperative Contrast Enhanced Mammography in Staging of Malignant Breast Lesions (PROCEM): A Randomized Controlled Trial.

This prospective, multicenter randomized controlled trial evaluated whether preoperative contrast-enhanced mammography (CEM) adds value to standard imaging for staging early-stage breast cancer in women eligible for…

RadiologyNov 1, 2026Read summary
Clinical ResearchCardiology

Socio-economic status, cardiovascular risk factors, and coronary atherosclerosis: a SCOT-HEART trial analysis.

This post-hoc analysis of a multicentre randomised trial examined socioeconomic status (SES) in relation to coronary CT angiography (CCTA) plaque features, management, and cardiovascular outcomes.

Eur J Prev CardiolNov 11, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

The Effect of Shoulder Support on Shoulder Subluxation in Stroke Survivors Based on Ultrasonography Findings: A Randomized Clinical Trial.

This single-blind randomized controlled trial assessed whether adding a standardized shoulder support to conventional rehabilitation improved shoulder subluxation, pain, upper-limb motor function, or independence in 40…

Musculoskeletal CareNov 11, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Conservative versus surgical management of traumatic acute subdural hematoma: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis compared surgical with conservative management of traumatic acute subdural hematoma in adults.

Neurosurg RevNov 11, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Imaging-Based AI for Predicting Pathological Complete Response in Esophageal Cancer After Neoadjuvant Therapy: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed imaging-based AI models for predicting pathological complete response after neoadjuvant therapy for esophageal cancer, separating internal from external validation.

J Med Internet ResNov 11, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Anatomy-specific Performance of CTA-based AI for Anterior Circulation Occlusion: Systematic Review and Meta-analysis.

This prospectively registered systematic review and diagnostic meta-analysis assessed CTA-based artificial intelligence for detecting anterior-circulation occlusions, using 31 reports involving 15 708 patients.

Radiol Artif IntellNov 1, 2026Read summary
Clinical ResearchUrologyOpen access

Diagnostic yield and early outcomes of radical prostatectomy without prior histopathologic diagnosis: a single-arm systematic review and meta-analysis.

This single-arm systematic review and random-effects meta-analysis assessed radical prostatectomy without prior histopathologic confirmation in adult men with high clinical suspicion of clinically significant prostate…

World J UrolNov 10, 2026Read summary
Clinical ResearchPsychiatryOpen access

Structural Brain Correlates of Bulimia Nervosa Diagnosis and Symptom Severity: A Coordinated ENIGMA Eating Disorders Working Group Analysis.

This coordinated, international case-control meta-analysis examined structural MRI correlates of bulimia nervosa (BN) diagnosis and symptom severity across 17 cohorts at 13 sites.

JAMA PsychiatryNov 1, 2026Read summary

Showing 12 of 91 publications that cleared our clinical screen in the last 14 days.

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