Rethinking Transfusion Strategies in CABG: Acute Normovolaemic Haemodilution <em>versus</em> Conventional Transfusion: A Systematic Review.

J Coll Physicians Surg PakSep 1, 2026
Clinical ResearchCardiothoracic SurgeryAnesthesiology

Diyan Muhammad, Taimur Asif Ali, Muhammad Anas Khan et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review evaluated the effectiveness of acute normovolaemic haemodilution (ANH) compared to conventional transfusion practices in patients undergoing coronary artery bypass grafting (CABG). Eighteen randomised controlled trials were analyzed, revealing that ANH significantly reduced the need for allogeneic blood transfusion while maintaining haemodynamic stability and postoperative recovery.

Key findings

  • ANH reduced the need for allogeneic blood transfusion compared to conventional methods.
  • Moderate improvements in coagulation preservation were observed with ANH.
  • Myocardial protection was enhanced with ANH, though evidence certainty varied.

Why it matters

Understanding the benefits of ANH in CABG can help clinicians optimize blood conservation strategies, potentially reducing reliance on allogeneic transfusions and improving patient outcomes during and after surgery.

Source

PubMed · PMID 42698250

Published in J Coll Physicians Surg Pak. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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