Dyke-Davidoff-Masson Syndrome: Neuroimaging Perspective of Infantile Versus Adult Presentation.

Ann Afr MedJul 2, 2026 (epub)
Case ReportRadiology (Diagnostic)NeurologyPediatrics

Sanjay M Khaladkar, Gogineni Rahul, Mihir Wadhawan

✦ AI-curated · Sources linked

Case in brief

The report compared neuroimaging in a 22-year-old man with refractory epilepsy and a 12-month-old infant, both showing features of Dyke-Davidoff-Masson syndrome (DDMS), a condition involving cerebral hemiatrophy after congenital or early acquired brain injury. The adult had cerebral hemiatrophy with well-developed calvarial thickening, whereas the infant had marked hemiatrophy but minimal osseous remodeling. The contrasting findings illustrate how the radiological appearance of DDMS evolves with age.

What made this case unusual

The comparison showed marked cerebral hemiatrophy in the infant despite minimal skull remodeling, contrasting with the adult’s well-developed calvarial thickening.

Diagnostic / clinical pearl

Interpret calvarial and paranasal sinus remodeling in the context of age: these compensatory changes may be minimal in an infant even when cerebral hemiatrophy is marked.

Source

PubMed · PMID 42390338

Published in Ann Afr Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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