Histiocytic Sarcoma of the Eyelid: An Uncommon Presentation of a Rare Neoplasm.
Grace Baldwin, Lisa Y Lin, Anna M Stagner et al.
✦ AI-curated · Sources linked
Case in brief
An 80-year-old man presented with a rapidly enlarging lesion of the left lower eyelid over 4 months. Shave biopsy showed histologic and immunophenotypic features most consistent with morphologically low-grade histiocytic sarcoma. Complete excision, including additional 2 mm peripheral and deep margins, achieved clear margins. Systemic evaluation and whole-body imaging found no metastases or associated malignancy. Radiation was deferred in favor of close observation every 3 months; at 2 years after presentation, there was no evidence of recurrence.
What made this case unusual
The tumor presented in eyelid skin, an exceptionally uncommon site for histiocytic sarcoma; the abstract notes only one prior eyelid-skin case.
Diagnostic / clinical pearl
A rapidly growing eyelid lesion can represent histiocytic sarcoma; biopsy with histologic and immunophenotypic assessment established the diagnosis in this case.