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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedClinical ResearchOphthalmology

Dexamethasone Eye Drops to Prevent Treatment-Requiring Retinopathy of Prematurity: The DROPROP Randomized Clinical Trial.

JAMA PediatrNov 1, 2026Open access

The DROPROP double-masked, multicentre randomised clinical trial tested whether topical dexamethasone could prevent progression to treatment-requiring type 1 retinopathy of prematurity (ROP) in preterm infants born…

Why it matters

Treatment-requiring ROP currently calls for invasive interventions intended to prevent blindness. A topical approach could offer a less invasive means of reducing progression in preterm infants, but this trial’s…

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Also worth knowing

Clinical ResearchOphthalmologyOpen access

Retinal and choroidal changes on optical coherence tomography in pre-eclampsia: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled observational studies comparing OCT measures in women with pre-eclampsia (PE) and control groups.

Int OphthalmolNov 7, 2026Read summary
Clinical ResearchOphthalmology

Risk of retinal vascular occlusion following COVID-19 vaccination: A meta-analysis of nearly 15 million individuals.

This systematic review and meta-analysis assessed retinal vascular occlusion after COVID-19 vaccination using five observational studies with 14,877,781 reported participants.

Medicine (Baltimore)Nov 6, 2026Read summary
Case ReportAnesthesiologyOpen access

Esketamine-Based Versus Sevoflurane-Based Anesthesia with Dexmedetomidine for Emergence Agitation in Pediatric Corneal Suture Removal: A Randomised Controlled Trial.

Corneal suture removal, particularly microsurgery requiring complete immobility, demands adequate anesthetic depth while ensuring rapid recovery.

Drug Des Devel TherNov 6, 2026Read case
Clinical ResearchOphthalmology

The impact of nutrition on glaucoma progression: evidence from systematic literature review and meta-analysis.

This systematic review and meta-analysis assessed whether dietary factors or nutritional supplements affect glaucoma progression in adults.

Int OphthalmolNov 5, 2026Read summary
Clinical ResearchOphthalmology

Visual Perceptual Learning Based on Adaptive Contrast Detection Training Enhances Vision and Contrast Sensitivity in Diabetic Retinopathy.

This randomized controlled trial evaluated 3-month home-based visual perceptual learning (VPL) in people with diabetic retinopathy who had received routine therapies.

Invest Ophthalmol Vis SciNov 2, 2026Read summary
Clinical ResearchOphthalmology

Randomized Single-Masked Study of Preservative-Free Versus Preserved Hyaluronic Acid in Dry Eye Disease.

This randomized, single-masked, 6-month trial compared preservative-free hyaluronic acid (PF HA) with benzalkonium chloride-preserved hyaluronic acid (BAK HA) in 47 patients with dry eye disease; 43 completed the study.

Transl Vis Sci TechnolNov 2, 2026Read summary
Clinical ResearchOphthalmology

Anterior Chamber Depth Changes: After Phacoemulsification in Eyes With Pseudoexfoliation Syndrome Versus Control Eyes: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis compared anterior chamber depth (ACD) before and after phacoemulsification in eyes with pseudoexfoliation syndrome (PEX) and control eyes.

J Refract SurgNov 1, 2026Read summary
Clinical ResearchOphthalmology

In-the-Bag Stability of a New Hydrophilic Acrylic Toric Intraocular Lens.

This single-centre, prospective interventional clinical trial assessed in-the-bag stability of the RayOne EMV toric intraocular lens in 119 eyes of 79 patients with age-related cataract over 6 months.

J Refract SurgNov 1, 2026Read summary
Clinical ResearchOphthalmology

First-in-Human Regulatory T Cell-Derived Exosomes Plus Ranibizumab for Refractory nAMD.

This single-centre, prospective, open-label phase 1a dose-escalation trial evaluated the safety and maximum tolerated dose of intravitreal autologous regulatory T cell-derived exosomes (TregExo) coformulated with…

J Extracell VesiclesNov 1, 2026Read summary
Case ReportOphthalmologyOpen access

STAT6-positive solitary fibrous tumour of the lacrimal gland with floret-type giant cells: a rare case report.

A 52-year-old man presented with five months of enlarging left lacrimal swelling, proptosis, and mildly reduced visual acuity. CT showed a well-defined 9 × 12 mm orbital lesion without bone erosion or local invasion.

BMC OphthalmolNov 5, 2026Read case
Case ReportOphthalmology

Clinical Reasoning: A 68-Year-Old Woman With Bilateral Optic Disc Edema.

A 68-year-old immunocompetent woman presented with headache, vertigo, and diplopia. Examination revealed bilateral optic disc edema.

NeurologyNov 5, 2026Read case

Showing 12 of 22 publications that cleared our clinical screen in the last 14 days.

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