Effects of repeated periods of high-intensity interval training on myocardial function in patients with metabolic syndrome: A 16-month follow-up.

J CardiolMay 4, 2026 (epub)
Clinical ResearchCardiologyEndocrinology

Juan F Ortega, Eva García-Camacho, Alejandro Gadella-Fernández et al.

✦ AI-curated · Sources linked

In 30 seconds

This randomized controlled trial investigated the effects of two periods of high-intensity interval training (HIIT) on myocardial function in 88 middle-aged patients with metabolic syndrome over 16 months. The study found that HIIT significantly improved left ventricle global longitudinal strain (LV-GLS) and early diastolic function compared to standard medical treatment alone, with a notable group*time interaction (p=0.002).

Key findings

  • LV-GLS improved progressively after two HIIT periods compared to control (p=0.002).
  • LV-early rapid filling parameters also showed significant improvement in the HIIT group (p=0.028).
  • Maximal oxygen consumption (VO2max) increased only in the HIIT group (p=0.002).

Why it matters

Improving myocardial function in patients with metabolic syndrome is crucial, as these individuals are at increased risk for cardiovascular disease. This study suggests that incorporating HIIT into treatment regimens may enhance cardiac health in this population.

Source

PubMed · PMID 42086168

Published in J Cardiol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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