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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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Case ReportOncology (Medical)Open access

Pediatric suprasellar primary CNS lymphoma with cavernous sinus invasion and ischemic stroke: a case report and systematic review.

A 12-year-old immunocompetent girl presented with high fever, severe headache, and diplopia, followed by rapid neurological deterioration.

Childs Nerv SystNov 3, 2026Read case
Case ReportInfectious DiseasesOpen access

Measles-like hypermutation of a Newcastle disease virus drives fatal encephalitis during BCMA × CD3 T-cell-redirecting immunotherapy.

A patient with multiple myeloma receiving maintenance teclistamab, daratumumab, and lenalidomide developed rapidly progressive brainstem-cerebellar encephalitis.

Acta NeuropatholNov 11, 2026Read case
Case ReportNeurosurgeryOpen access

Multifocal intradural extramedullary myxopapillary ependymoma of the spine.

A 34-year-old man presented with sudden severe non-radicular low-back pain but no neurological deficit. MRI showed multiple enhancing intradural extramedullary lesions from T12-L1 to S1; the dominant T12-L1 lesion…

J Cancer Res Clin OncolNov 9, 2026Read case
Case ReportOncology (Medical)

Progression-Associated Loss of SMARCB1/INI1 Expression in Mismatch Repair-Deficient Glioblastoma.

A patient with mismatch repair-deficient glioblastoma had a recurrent tumor in which testing identified a second SMARCB1 mutation and complete loss of SMARCB1/INI1 protein expression.

Neuropathol Appl NeurobiolNov 7, 2026Read case
Case ReportOncology (Medical)

Primary Synovial Sarcoma of the Thyroid Gland Presenting With Early Pulmonary Metastasis: Diagnostic Pathway, SS18 Gene Fusion Confirmation, and Clinical Course.

A 47-year-old woman presented with dysphagia and a left-sided neck mass. Initial fine-needle aspiration was non-diagnostic; repeat sampling suggested a spindle cell neoplasm.

Am J Case RepNov 11, 2026Read case
Case ReportOrthopedic Surgery

Coracoid Process Osteochondroma: Diagnostic Considerations and Detailed Approach for Management: Case Report and Literature Review.

A 21-year-old woman was found to have an osteochondroma arising from the tip of the coracoid process. The report describes preoperative clinical assessment and radiological investigation, with histopathological…

JBJS Case ConnectNov 11, 2026Read case
Case ReportPediatrics

Intestinal tuberculosis with multiple intestinal perforations in a 5-month-old infant: The role of metagenomic next-generation sequencing: a case report and literature review.

A 5-month-old boy presented with fever and abdominal distension that progressed to intestinal obstruction and multiple perforations involving the distal ileum and appendiceal region.

Medicine (Baltimore)Nov 6, 2026Read case
Case ReportHematology

Assay-aware flow-cytometric interpretation of relapsed B-cell precursor acute lymphoblastic leukemia after sequential CD19- and CD22-directed therapy: A case report.

A 73-year-old woman with B-cell precursor acute lymphoblastic leukemia developed marrow relapse after blinatumomab exposure.

Medicine (Baltimore)Nov 6, 2026Read case
Case ReportNeurologyOpen access

Erdheim-Chester disease: a diagnostic dilemma - a report of four cases.

Four adults aged 27–40 years presented with neurological Erdheim-Chester disease (ECD), with manifestations including cerebellar ataxia, dysarthria, tremor, visual deterioration, and headache.

Neurol SciNov 5, 2026Read case
Case ReportOphthalmologyOpen access

STAT6-positive solitary fibrous tumour of the lacrimal gland with floret-type giant cells: a rare case report.

A 52-year-old man presented with five months of enlarging left lacrimal swelling, proptosis, and mildly reduced visual acuity. CT showed a well-defined 9 × 12 mm orbital lesion without bone erosion or local invasion.

BMC OphthalmolNov 5, 2026Read case
Case ReportNeurologyOpen access

Late-onset Niemann-Pick C disease in a patient with spastic ataxia and hyperkinetic involuntary movements: a case report.

A woman with late-onset Niemann-Pick disease type C1 presented from age 50 with progressive postural instability, falls, spastic ataxia, and prominent upper-limb hyperkinetic movements.

Mol Biol RepNov 4, 2026Read case

Showing 12 of 52 publications that cleared our clinical screen in the last 14 days.

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