Trending Now

Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedClinical ResearchOphthalmology

Dexamethasone Eye Drops to Prevent Treatment-Requiring Retinopathy of Prematurity: The DROPROP Randomized Clinical Trial.

JAMA PediatrNov 1, 2026Open access

The DROPROP double-masked, multicentre randomised clinical trial tested whether topical dexamethasone could prevent progression to treatment-requiring type 1 retinopathy of prematurity (ROP) in preterm infants born…

Why it matters

Treatment-requiring ROP currently calls for invasive interventions intended to prevent blindness. A topical approach could offer a less invasive means of reducing progression in preterm infants, but this trial’s…

Read summary

Also worth knowing

Clinical ResearchOphthalmologyOpen access

Retinal and choroidal changes on optical coherence tomography in pre-eclampsia: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled observational studies comparing OCT measures in women with pre-eclampsia (PE) and control groups.

Int OphthalmolNov 7, 2026Read summary
Clinical ResearchOphthalmology

Risk of retinal vascular occlusion following COVID-19 vaccination: A meta-analysis of nearly 15 million individuals.

This systematic review and meta-analysis assessed retinal vascular occlusion after COVID-19 vaccination using five observational studies with 14,877,781 reported participants.

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchOphthalmology

The impact of nutrition on glaucoma progression: evidence from systematic literature review and meta-analysis.

This systematic review and meta-analysis assessed whether dietary factors or nutritional supplements affect glaucoma progression in adults.

Int OphthalmolNov 5, 2026Read summary
Clinical ResearchOphthalmology

Visual Perceptual Learning Based on Adaptive Contrast Detection Training Enhances Vision and Contrast Sensitivity in Diabetic Retinopathy.

This randomized controlled trial evaluated 3-month home-based visual perceptual learning (VPL) in people with diabetic retinopathy who had received routine therapies.

Invest Ophthalmol Vis SciNov 2, 2026Read summary
Clinical ResearchOphthalmology

Randomized Single-Masked Study of Preservative-Free Versus Preserved Hyaluronic Acid in Dry Eye Disease.

This randomized, single-masked, 6-month trial compared preservative-free hyaluronic acid (PF HA) with benzalkonium chloride-preserved hyaluronic acid (BAK HA) in 47 patients with dry eye disease; 43 completed the study.

Transl Vis Sci TechnolNov 2, 2026Read summary
Clinical ResearchOphthalmology

Anterior Chamber Depth Changes: After Phacoemulsification in Eyes With Pseudoexfoliation Syndrome Versus Control Eyes: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis compared anterior chamber depth (ACD) before and after phacoemulsification in eyes with pseudoexfoliation syndrome (PEX) and control eyes.

J Refract SurgNov 1, 2026Read summary
Clinical ResearchOphthalmology

In-the-Bag Stability of a New Hydrophilic Acrylic Toric Intraocular Lens.

This single-centre, prospective interventional clinical trial assessed in-the-bag stability of the RayOne EMV toric intraocular lens in 119 eyes of 79 patients with age-related cataract over 6 months.

J Refract SurgNov 1, 2026Read summary
Clinical ResearchOphthalmology

First-in-Human Regulatory T Cell-Derived Exosomes Plus Ranibizumab for Refractory nAMD.

This single-centre, prospective, open-label phase 1a dose-escalation trial evaluated the safety and maximum tolerated dose of intravitreal autologous regulatory T cell-derived exosomes (TregExo) coformulated with…

J Extracell VesiclesNov 1, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Endoscopic dacryocystorhinostomy with versus without silicone intubation in chronic dacryocystitis: a comparative meta-analysis.

This systematic review and meta-analysis compared endoscopic dacryocystorhinostomy (EN-DCR) with versus without silicone intubation for chronic dacryocystitis.

Int OphthalmolNov 5, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Toxoplasmosis-associated optic neuropathies: a systematic review and meta-analysis of clinical characteristics, diagnosis, and outcomes.

This systematic review and meta-analysis examined optic neuropathies associated with ocular toxoplasmosis (OT), combining observational studies and case reports.

Int OphthalmolOct 31, 2026Read summary
Clinical ResearchOphthalmologyOpen access

The risk of rhegmatogenous retinal detachment associated with topical pilocarpine: a systematic review.

This systematic review assessed whether topical pilocarpine is associated with rhegmatogenous retinal detachment (RRD) in patients aged 40 years or older, synthesising 10 comparative studies.

Int OphthalmolNov 2, 2026Read summary
Looking for an earlier article?Everything that has appeared in Trending is in the archive.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.