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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchOphthalmology

Effect of a modified soft contact lens combined with a noncontact wide-angle viewing system during vitrectomy.

Medicine (Baltimore)Sep 4, 2026

This randomized controlled trial evaluated the effectiveness of a modified soft contact lens (MSCL) in maintaining visual clarity and protecting the cornea during vitrectomy.

Why it matters

Maintaining intraoperative visual clarity and protecting the cornea are critical during vitrectomy. The use of MSCL may enhance surgical outcomes and patient comfort without increasing surgical time.

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Also worth knowing

Clinical ResearchOphthalmology

Autologous bone grafts versus alloplastic implants for orbital floor reconstruction: a systematic review and meta-analysis.

This systematic review and meta-analysis compared autologous bone grafts and alloplastic implants for orbital floor reconstruction in 2,119 patients.

Oral Maxillofac SurgSep 3, 2026Open accessRead summary
Clinical ResearchOphthalmology

Evaluation of a cornea-specialized large language model for diagnostic and management accuracy in complex corneal cases.

This randomized controlled trial assessed the effectiveness of a cornea-specialized large language model (LLM) in improving diagnostic and management accuracy in complex corneal cases among three cornea trainees.

Int OphthalmolSep 2, 2026Open accessRead summary
Clinical ResearchOphthalmology

ENDOPHTHALMITIS INCIDENCE AFTER VITRECTOMY: A Systematic Review and Meta-Analysis of Risk Factors and Prevention Strategy.

This systematic review and meta-analysis evaluated the incidence of endophthalmitis after vitrectomy across 69 studies involving 1,979,160 procedures. The overall incidence was found to be 0.14%.

RetinaSep 1, 2026Read summary
Clinical ResearchOphthalmology

Visual performance and patient-reported outcomes of an EDF intraocular lens compared with a monofocal intraocular lens: randomized trial.

This randomized controlled trial evaluated the visual performance and patient-reported outcomes of the Acunex Vario AN6V extended depth of field (EDF) intraocular lens compared to the Acunex AN6 monofocal lens in…

J Cataract Refract SurgSep 1, 2026Open accessRead summary
Clinical ResearchOphthalmology

EFFICACY OF COMBINED DEXAMETHASONE IMPLANT AND NAVIGATED SUBTHRESHOLD MICROPULSE YELLOW LASER IN DIABETIC MACULAR EDEMA.

This randomized controlled trial evaluated the efficacy of combining intravitreal dexamethasone implant with navigated subthreshold micropulse laser versus dexamethasone monotherapy in 80 eyes with diabetic macular…

RetinaSep 1, 2026Read summary
Clinical ResearchOphthalmology

Efficacy of capsular bag fixation versus ciliary sulcus fixation IOL implantation in children patients: meta-analysis.

This meta-analysis evaluated the safety and efficacy of ciliary sulcus versus capsular bag fixation for intraocular lens implantation in 843 pediatric patients.

Int OphthalmolSep 1, 2026Open accessRead summary
Clinical ResearchOphthalmology

Ocular gene therapy targeting retinal angiogenesis and vascular leakage: translational and clinical evidence from a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated ocular gene therapy's effects on retinal angiogenesis and vascular leakage in various studies.

AngiogenesisAug 31, 2026Open accessRead summary
Clinical ResearchOphthalmology

Visual acuity outcome and complications of cataract surgery in Nigeria: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated visual acuity outcomes and complications following cataract surgery in Nigeria, analyzing data from 16 studies involving 3631 eyes.

Int HealthSep 1, 2026Open accessRead summary
Clinical ResearchGeneral Surgery

Costs of surgeries in low- and middle-income countries: a systematic literature review.

This systematic review analyzed 74 studies on surgical costs in low- and middle-income countries (LMICs) from January 2000 to June 2023.

BMJ Glob HealthSep 4, 2026Read summary
Clinical ResearchOphthalmology

Long-term outcomes after a randomized phase II trial of nerve growth factor eye drops for optic pathway gliomas: four-year follow-up findings in children.

This study evaluated long-term outcomes in children with optic pathway gliomas (OPG) who previously participated in a randomized phase II trial of murine nerve growth factor (mNGF) eye drops.

J NeurooncolSep 1, 2026Open accessRead summary
Clinical ResearchOphthalmology

Neuroprotective and anti-inflammatory strategies for corneal nerve regeneration and ocular surface stability after corneal refractive surgeries: systematic review.

This systematic review evaluated controlled trials on neuroprotective and anti-inflammatory therapies for corneal nerve regeneration and ocular surface stability post-refractive surgery.

J Cataract Refract SurgSep 1, 2026Read summary

Showing 12 of 15 publications that cleared our clinical screen in the last 14 days.

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