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799 articles
November 202624
Exploring the Association Between Cannabis Use and Male Reproductive Parameters: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined associations between cannabis use and male reproductive parameters. It included 18 studies reporting sperm outcomes (5,766 patients; 6,231 samples) and hormonal outcomes…
Effects of Polyphenols on Gut Health and Inflammation in Overweight and Obese Populations: A Systematic Review and Meta-analysis of Dose, Duration, and Food Matrix.
This systematic review and meta-analysis assessed polyphenol interventions and gut microbiota and inflammatory biomarkers in people with overweight or obesity, drawing on 32 randomized controlled trials.
2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.
This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.
Effects of Vitamin D Supplementation in Combination With Exercise Training on Body Composition and Muscular Strength in Adults: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
This systematic review and dose-response meta-analysis of randomized controlled trials assessed whether vitamin D supplementation added to exercise improves body composition or muscular strength compared with exercise…
Association Between Vitamin D Status and Nocturnal Lower Urinary Tract Symptoms: A Pooled Analysis.
This systematic review and meta-analysis assessed associations between vitamin D status or intake and nocturnal lower urinary tract symptoms (nLUTS), drawing on 17 studies: 5 randomised trials, 2 cohort studies, 4…
The Role of Diet and Physical Activity in Gut Microbiota Modulation in Type 2 Diabetes Management: A Systematic Review of Clinical Trials.
This systematic review assessed clinical trials of dietary and physical activity interventions and gut microbiota in adults with type 2 diabetes or prediabetes.
Regimens of vitamin D supplementation for women during pregnancy.
This updated Cochrane systematic review and meta-analysis assessed randomised trials of vitamin D regimens during pregnancy in women without pre-existing conditions or multiple pregnancies.
Whole-grain consumption and cardiometabolic risk: a meta-analysis of randomized trials.
This meta-analysis of randomized trials assessed how whole-grain intake affects cardiometabolic risk factors. It included 87 trials (101 publications) and estimated effects per 48 g/day increment in whole grains (dry…
Cardiovascular outcomes of glucagon-like peptide-1 receptor agonists: A systematic review.
This systematic review evaluated 12 cardiovascular outcome-based randomised controlled trials of GLP-1 receptor agonists (GLP1RAs): 10 in people with type 2 diabetes (T2D), one in people with overweight or obesity and…
Sex differences in cardiovascular-kidney-metabolic syndrome: the FINE-HEART pooled analysis.
This prespecified pooled analysis combined participant-level data from three trials involving people with chronic kidney disease and type 2 diabetes or heart failure with mildly reduced or preserved ejection fraction.
Machine Learning Models for Glycemic Prediction in Type 1 and Type 2 Diabetes: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed machine-learning models predicting glucose values or glycemic events in people with type 1, type 2, mixed, or unclear diabetes.
Oral Acarbose Inhibits Baseline Salivary Amylase and Blunts Early Postprandial Glycemia: Randomized Cross-Over Study.
This single-blinded, placebo-controlled randomized cross-over trial examined whether oral acarbose inhibition of salivary α-amylase affects postprandial blood glucose in 15 young, healthy women.
Effects of vitamin D supplementation on vitamin D status and physical performance in football players: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed controlled intervention studies of vitamin D supplementation in association football and futsal players.
Peptides for male sexual dysfunction: a systematic review of emerging evidence.
This PRISMA-guided systematic review assessed human studies of peptide-based therapies for male sexual function, reproductive hormones, and semen parameters.
Plozasiran for Severe Hypertriglyceridemia and Risk of Pancreatitis.
Two double-blind, placebo-controlled randomized trials evaluated plozasiran in 757 adults with severe hypertriglyceridemia.
Targeting hormone conversion through dietary fiber improves polyendocrine metabolic ovarian syndrome.
This randomized controlled clinical trial examined a combination of inulin, resistant starch, and β-glucan in patients with polyendocrine metabolic ovarian syndrome (PMOS).
Sequential therapy with anlotinib and radioiodine for distant metastatic differentiated thyroid cancer: a phase II clinical trial.
This prospective, single-arm phase II trial evaluated sequential anlotinib and radioiodine (RAI) in patients with measurable distant metastatic differentiated thyroid cancer (DTC).
Effect of Kunxian capsule, a novel Tripterygium wilfordii preparation, on reducing proteinuria and slowing renal function decline in diabetic kidney disease: a 48-week randomized controlled trial.
This 48-week randomized controlled trial assigned 80 patients with diabetic kidney disease to irbesartan-based standard therapy with or without adjunctive Kunxian capsule.
Effects of the integrated care on healthcare utilization and costs among patients with diabetes and depression: a cluster-randomized controlled trial.
This cluster-randomized controlled trial in community health centers in China assessed whether Community-based Integrated Care for Patients with Diabetes and Depression affected healthcare use and costs.
Motivation in adolescents and caretakers undergoing a weight management program - longitudinal data from the cluster-randomized, motivation-focused STARKIDS trial.
This secondary analysis of the cluster-randomized STARKIDS trial compared motivational changes among adolescents with overweight or obesity and their caretakers in a motivation-focused weight management program versus…
Barriers to Gender-Affirming Care for Nonbinary People: A Systematic-Narrative Hybrid Literature Review.
This systematic-narrative hybrid literature review synthesised qualitative, quantitative and mixed-methods research, alongside systematic and scoping reviews, on barriers to gender-affirming care for nonbinary people.
Fluid choice in pediatric diabetic ketoacidosis: a Systematic Review and Meta-Analysis.
This systematic review and meta-analysis compared balanced electrolyte solutions (BES) with 0.9% saline for fluid resuscitation in children with diabetic ketoacidosis (DKA), including randomized trials and observational…
Effects of exercise interventions on leptin and ghrelin levels in middle-aged and older adults with overweight or obesity: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed randomized controlled trials of exercise interventions in middle-aged and older adults with overweight or obesity, examining changes in leptin and ghrelin.
Effect of topical insulin in diabetic foot ulcer healing among patients with diabetes in Asia: a systematic review.
This systematic review assessed topical insulin for diabetic foot ulcer healing in patients with diabetes in Asian countries.
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