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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedCase ReportEndocrinology

Acquired apparent mineralocorticoid excess induced by compound glycyrrhizin tablets: A case report and literature review.

Int J Clin Pharmacol TherSep 9, 2026

A 57-year-old male developed severe hypertension and hypokalemia after 30 days of treatment with compound glycyrrhizin tablets.

Clinical pearl

Clinicians should consider acquired apparent mineralocorticoid excess in patients presenting with hypertension and hypokalemia, particularly those using glycyrrhizin-containing products.

Read case

Also worth knowing

Case ReportMedical Genetics

A familial case of FLAD1 protein deficiency associated with impaired adrenal steroidogenesis.

This report details two siblings with compound heterozygous mutations in the FLAD1 gene, resulting in adrenal insufficiency, a previously unreported association.

JCI InsightSep 8, 2026Read case
Case ReportVascular Surgery

Underlying vascular and mechanical commonalities of venous leg ulcers and diabetic foot ulcers: a unified framework for management.

A patient with diabetes presented with both neuropathic and venous leg ulcers (VLUs). The case emphasized the importance of comprehensive vascular and biomechanical evaluations in managing these coexisting conditions.

J Wound CareSep 4, 2026Read case
Case ReportMedical Genetics

Successful pregnancy after in vitro fertilization-embryo transfer in a patient with cytochrome P450 oxidoreductase deficiency and a double uterus: Case report.

A 29-year-old woman with a history of 7 years of infertility was diagnosed with cytochrome P450 oxidoreductase deficiency and uterus didelphys.

Medicine (Baltimore)Sep 4, 2026Read case
Case ReportMedical Genetics

Case report: Tirzepatide-responsive refractory diabetes mellitus in an adult female with prader-willi syndrome.

A woman with Prader-Willi syndrome (PWS) presented with poorly controlled diabetes mellitus, characterized by severe insulin resistance and uncontrollable hyperphagia leading to morbid obesity.

Medicine (Baltimore)Sep 4, 2026Read case
Case ReportEndocrinology

Primary Care Recognition of Rabson-Mendenhall Syndrome Despite Absence of Classical Diabetic Symptoms.

A 10-year-old girl presented with intermittent bilateral leg pain and excessive hunger, lacking classical diabetic symptoms. Examination revealed extensive acanthosis nigricans, moderate hirsutism, and dental defects.

Am J Case RepSep 5, 2026Read case
Case ReportOncology (Medical)

Intravascular large B-cell lymphoma with reversible central hypopituitarism.

A woman in her late 60s presented with fever and general fatigue. Investigations showed bicytopenia, splenomegaly, and central hypothyroidism.

BMJ Case RepSep 7, 2026Read case
Case ReportMedical Genetics

Extra-Endocrine Features in Infancy as Early Clues to MEN2B.

This case series discusses five pediatric patients diagnosed with multiple endocrine neoplasia type 2B (MEN2B), all carrying the RET proto-oncogene mutation (M918T).

PediatricsSep 1, 2026Read case
Case ReportMedical Genetics

Calcitonin-negative medullary thyroid carcinoma in a young adult.

A young woman in her early 20s presented with a thyroid nodule and normal serum calcitonin levels, which typically indicate the absence of medullary thyroid carcinoma (MTC).

BMJ Case RepAug 31, 2026Read case
Case ReportEndocrinology

Clinical and Biochemical Recovery From Immune Checkpoint Inhibitor-Induced Diabetes With Seroconversion of GAD Antibodies.

A patient with melanoma developed abrupt-onset symptomatic hyperglycemia and mild ketosis after treatment with ipilimumab and nivolumab, indicating immune checkpoint inhibitor-induced diabetes (ICI-D).

Diabetes CareSep 1, 2026Open accessRead case
Case ReportHematology

Type 1 Diabetes Driven by Residual Recipient T Cells After Hematopoietic Cell Transplantation: A Case Report.

A patient developed type 1 diabetes following haploidentical hematopoietic cell transplantation. Analysis revealed an expanded population of islet-specific CD4+ T cells in the recipient, predominantly restricted by…

Diabetes CareSep 1, 2026Open accessRead case
Case ReportEndocrinology

Thyroid-stimulating hormone-secreting pituitary neuroendocrine tumor (TSH-PitNet) diagnosed during pregnancy and treated with a somatostatin analog.

A woman in her mid-20s presented during pregnancy with hyperemesis gravidarum and mild palpitations. Blood tests indicated elevated thyroid hormone levels with non-suppressed TSH, leading to the diagnosis of a…

Taiwan J Obstet GynecolSep 1, 2026Read case

Showing 12 of 13 publications that cleared our clinical screen in the last 14 days.

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