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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedCase ReportRheumatology

Rheumatoid factor positivity in ANCA-negative eosinophilic granulomatosis with polyangiitis: cardiac mimicry, mononeuritis multiplex, and long-term outcome in a case-based systematic review.

Rheumatol IntNov 10, 2026Open access

A 42-year-old woman with long-standing asthma and rheumatoid factor (RF) of 322 IU/mL presented with myocardial infarction-like cardiac involvement despite non-obstructive coronary arteries.

Clinical pearl

High RF positivity does not exclude EGPA. In a patient with asthma, eosinophilia, and compatible ENT, neurologic, or cardiac manifestations, consider EGPA even when ANCA is negative and RF is elevated.

Read case

Also worth knowing

Case ReportNeurology

Time- and posture-specific management of severe supine hypertension and neurogenic orthostatic hypotension in diabetic autonomic neuropathy: A case report.

A 63-year-old man with insulin-treated type 2 diabetes and hypertension developed worsening orthostatic dizziness and recurrent syncope after antihypertensive intensification, including a rib fracture and loss of…

Medicine (Baltimore)Nov 6, 2026Read case
Case ReportCardiology

Perinatal multidisciplinary management for neonates with prenatally-diagnosed congenital complete heart block undergoing early epicardial pacemaker implantation: a retrospective single-center case series.

This retrospective single-center series described four neonates with prenatally diagnosed isolated congenital complete heart block who required early epicardial pacemaker implantation.

J Matern Fetal Neonatal MedNov 4, 2026Read case
Case ReportVascular Surgery

Radial Artery Pseudoaneurysm With Individualized Non-Operative Management: A 4-Case Series.

Four patients developed iatrogenic radial artery pseudoaneurysms after arterial access for blood pressure monitoring or coronary angiography. Management was tailored to hand circulation and pseudoaneurysm anatomy.

Am J Case RepNov 7, 2026Read case
Case ReportCardiology

Left Ventricular Free-Wall Injury During Emergency Pericardial Drainage After Percutaneous Coronary Intervention-Related Coronary Perforation.

A 63-year-old woman developed shock and an enlarging pericardial effusion after PCI for a severely calcified right coronary artery lesion complicated by perforation, which was sealed with a covered stent.

Am J Case RepNov 6, 2026Read case
Case ReportOncology (Medical)

Postoperative Neuromuscular Paresis and Overlap Syndrome Related to Immune Checkpoint Inhibitors: A Case Report.

A patient receiving immune checkpoint inhibitor therapy developed extremity paresis after proximal humerus resection and reconstruction.

JBJS Case ConnectNov 5, 2026Read case
Case ReportRheumatologyOpen access

Pulmonary-Cardiac Involvement in a Patient with IgA Vasculitis.

A 41-year-old woman with biopsy-proven IgA nephropathy presented with progressive dyspnea, hemoptysis, and a painful purpuric rash.

Methodist Debakey Cardiovasc JNov 3, 2026Read case
Case ReportCardiology

Recurrent Cardiac Cephalalgia: A Case Report and Pooled Narrative Review.

An elderly man with multiple cardiovascular risk factors and prior coronary artery disease treated with percutaneous coronary intervention had progressive exertional headaches over several years, without typical cardiac…

NeurologistNov 1, 2026Read case
Case ReportMedical GeneticsOpen access

Severe Atherogenic Dyslipidemia in Ataxia-Telangiectasia Despite Cachexia: Mechanistic Insights into Mitochondrial Dysfunction.

A 25-year-old woman with genetically confirmed ataxia-telangiectasia and extreme underweight (body mass index 12.5 kg/m²) developed severe mixed atherogenic dyslipidemia despite modest dietary fat intake and no…

Yale J Biol MedNov 4, 2026Read case
Case ReportMedical GeneticsOpen access

KARS1-Related Infantile-Onset Progressive Leukoencephalopathy With or Without Deafness: A Novel Variant and Phenotypic Expansion.

A two-year-old Iranian boy born to non-consanguineous parents presented with developmental delay, seizures, and sensorineural hearing loss.

J Mol NeurosciNov 3, 2026Read case
Case ReportEndocrinology

Clopidogrel-induced insulin autoimmune syndrome: A case report and analysis of clinical characteristics in Chinese patients.

A 69-year-old Chinese man developed hypoglycemic symptoms and was diagnosed with insulin autoimmune syndrome after starting clopidogrel.

J Int Med ResNov 3, 2026Read case
Case ReportPediatrics

False-Positive Prenatal Suspicion of Partial Anomalous Pulmonary Venous Connection: A Benign Confluence Variant Clarified by Cardiac CT.

Prenatal ultrasound raised suspicion of partial anomalous pulmonary venous connection (PAPVC). After birth, echocardiography—limited by acoustic windows and influenced by the prenatal interpretation—also suggested…

EchocardiographyNov 1, 2026Read case

Showing 12 of 13 publications that cleared our clinical screen in the last 14 days.

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