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1357 articles

November 202624

Clinical ResearchOphthalmologyOpen access

Endoscopic dacryocystorhinostomy with versus without silicone intubation in chronic dacryocystitis: a comparative meta-analysis.

This systematic review and meta-analysis compared endoscopic dacryocystorhinostomy (EN-DCR) with versus without silicone intubation for chronic dacryocystitis.

Int OphthalmolNov 5, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Socioeconomic Inequalities in Dietary and Physical Activity Behaviours Among Adolescents: A Systematic Review.

This systematic review synthesized observational evidence on socioeconomic position and dietary or physical activity behaviours among adolescents. Of 22,897 records identified, 38 studies met the eligibility criteria.

J Hum Nutr DietNov 4, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Maternal and Fetal Outcomes in Pregnant Women with Burn Injuries: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled maternal and fetal mortality in pregnant women with burn injuries, using observational studies and case series.

J Burn Care ResNov 4, 2026Read summary
Clinical ResearchAnesthesiology

Perioperative respiratory adverse events in children undergoing adenotonsillectomy with laryngeal mask airway versus endotracheal tube ventilation: multicentre, randomised controlled trial.

This multicentre, randomised, parallel-group trial compared laryngeal mask airway (LMA) with endotracheal tube (ETT) ventilation during adenotonsillectomy under general anaesthesia in 400 children aged 2 to under 7…

BMJNov 4, 2026Read summary
Clinical ResearchNephrologyOpen access

Proton pump inhibitors in prevention of cisplatin-induced nephrotoxicity: a systematic review.

This systematic review assessed whether proton pump inhibitor (PPI) co-administration prevents cisplatin-related kidney injury and whether it is safe.

Support Care CancerNov 4, 2026Read summary
Clinical ResearchNeurologyOpen access

Effects of Probiotics on Migraine in Children and Adults: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed probiotics for migraine prevention in placebo-controlled trials involving adults and children.

Curr Pain Headache RepNov 4, 2026Read summary
Clinical ResearchRheumatology

Conductive and sensorineural hearing impairment in juvenile idiopathic arthritis: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed middle-ear and cochlear function in children with juvenile idiopathic arthritis (JIA) compared with healthy controls.

Rheumatology (Oxford)Nov 4, 2026Read summary
Clinical ResearchCardiology

Safety and effectiveness of a novel dual-energy radiofrequency/pulsed field ablation catheter: 12-month results of the FlexPulse study.

The FlexPulse study was a global, prospective, single-arm, multicentre clinical trial evaluating a flexible-tip catheter that delivers radiofrequency and pulsed-field energy in people with symptomatic, drug-refractory…

EuropaceNov 4, 2026Read summary
Clinical ResearchPlastic Surgery

Classification Systems and Clinical Outcomes of Axillary Burn Contracture: A Systematic Review and Meta Analysis.

This systematic review and meta-analysis examined classification systems and surgical outcomes for axillary burn contracture.

J Burn Care ResNov 4, 2026Read summary
Clinical ResearchPulmonologyOpen access

Health-related quality of life measures in chronic pulmonary aspergillosis: a systematic review of psychometric validity.

This systematic review assessed health-related quality-of-life (HRQoL) measures and symptom scores used in chronic pulmonary aspergillosis (CPA), synthesising evidence from English-language studies published through May…

Eur Respir RevNov 4, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Health-centric information and moisture management for the adoption of postharvest practices to reduce mycotoxin risk: evidence from black pepper farmers in Sri Lanka.

This randomized controlled trial examined whether health-centric information and moisture-management interventions, alongside general mycotoxin information and government training, changed postharvest practices among…

Mycotoxin ResNov 4, 2026Read summary
Clinical ResearchNeurosurgery

Salovum® reduces mortality in isolated severe traumatic brain injury: a randomized phase II trial.

This prospective, double-blind, placebo-controlled phase II randomized trial tested Salovum® in adults with isolated severe traumatic brain injury receiving intracranial pressure monitoring and neurointensive care at a…

BrainNov 4, 2026Read summary
Clinical ResearchPediatricsOpen access

Motivation in adolescents and caretakers undergoing a weight management program - longitudinal data from the cluster-randomized, motivation-focused STARKIDS trial.

This secondary analysis of the cluster-randomized STARKIDS trial compared motivational changes among adolescents with overweight or obesity and their caretakers in a motivation-focused weight management program versus…

BMC MedNov 4, 2026Read summary
Clinical ResearchCardiology

A randomized comparison of comprehensive weight loss intervention vs. usual care on recurrences of atrial fibrillation in obese patients after catheter ablation: HOBIT-AF trial.

The HOBIT-AF randomized controlled trial tested whether a comprehensive weight-loss intervention reduced atrial fibrillation or atrial tachycardia (AF/AT) recurrence after catheter ablation in obese patients.

EuropaceNov 4, 2026Read summary
Clinical ResearchEndocrinology

Effects of the integrated care on healthcare utilization and costs among patients with diabetes and depression: a cluster-randomized controlled trial.

This cluster-randomized controlled trial in community health centers in China assessed whether Community-based Integrated Care for Patients with Diabetes and Depression affected healthcare use and costs.

Am J EpidemiolNov 4, 2026Read summary
Clinical ResearchRheumatology

The effect of exercise program applied to patients with scleroderma on functional outcomes: A randomized controlled trial.

This randomized controlled trial assessed whether an exercise program improved hand and mouth function and quality of life in 46 patients with systemic sclerosis.

Mod RheumatolNov 4, 2026Read summary
Clinical ResearchPulmonologyOpen access

The Association Between Chronic Obstructive Pulmonary Disease and Postoperative Delirium: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined whether chronic obstructive pulmonary disease (COPD) is associated with postoperative delirium (POD) in surgical patients.

Int J Chron Obstruct Pulmon DisNov 4, 2026Read summary
Clinical ResearchPsychiatry

What works for whom? A systematic mapping review of psychological treatments for adults with longstanding anorexia nervosa.

This systematic mapping review examined quantitative interventional studies of psychological treatments for adults with longstanding anorexia nervosa (AN), searching four databases for studies published between 2005 and…

Eat DisordNov 4, 2026Read summary
Clinical ResearchGeneral Surgery

Negative pressure incisional wound therapy for high-risk ventral hernia repair: a randomized controlled trial and meta-analysis.

This multicentre randomized controlled trial compared prophylactic negative pressure wound therapy (NPWT) with sterile dressings in adults with at least one risk factor for surgical-site complications undergoing ventral…

Can J SurgNov 4, 2026Read summary
Clinical ResearchOncology (Medical)

Longitudinal remodeling of the tumor-immune microenvironment during regorafenib, nivolumab, and chemotherapy in advanced gastric cancer.

This phase 1b/2 clinical trial evaluated first-line regorafenib, nivolumab, and chemotherapy in 30 patients with mismatch repair-proficient advanced gastric cancer, alongside longitudinal analysis of tumor biopsies.

Sci Transl MedNov 4, 2026Read summary
Clinical ResearchNeurology

Efficacy and safety of cenobamate in the treatment of drug-resistant epilepsy: a systematic review and meta-analysis in adult, pediatric, and combined populations.

This systematic review and random-effects meta-analysis assessed cenobamate efficacy and safety for drug-resistant epilepsy in adults, children, and mixed-age populations.

Eur J Clin PharmacolNov 4, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Effects of digital stress-management interventions in breast cancer patients 18 months after intervention access.

This randomized controlled trial examined whether app-based cognitive behavioral (CBI) or mindfulness-based (MBI) stress management was associated with improved outcomes 18 months after access began among patients with…

Breast Cancer Res TreatNov 4, 2026Read summary
Clinical ResearchOrthopedic Surgery

Interventions for adhesive capsulitis: systematic review and network meta-analysis of randomised controlled trials.

This systematic review and network meta-analysis compared treatments for adhesive capsulitis in adults, including 189 randomised controlled trials with 12 988 participants and 59 interventions.

BMJNov 4, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

The effect of a seven-week online mindfulness intervention on the relationship between menstrual symptoms and mental health - A non-randomized controlled trial.

This non-randomized controlled trial examined whether a seven-week online mindfulness-based intervention was associated with changes in the relationship between menstrual symptoms and mental health among 39 physically…

BMC PsycholNov 4, 2026Read summary

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