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1303 articles

October 202624

Clinical ResearchPsychiatry

Nutraceuticals and phytoceuticals in the treatment of bipolar disorder: A systematic review and network meta-analysis.

This systematic review and network meta-analysis assessed randomized controlled trials of nutraceuticals and phytoceuticals for bipolar disorder. Twenty-eight trials involving 2,222 participants evaluated 22 treatments.

Eur NeuropsychopharmacolOct 5, 2026Read summary
Case ReportPsychiatry

The role of PRKRA mutation in antipsychotic-induced extrapyramidal symptoms: a case report and implications for precision psychiatry.

A 43-year-old woman with atypical psychosis developed severe extrapyramidal symptoms after treatment with olanzapine, an antipsychotic described as having a lower propensity for these effects.

Psychiatr GenetOct 5, 2026Read case
Clinical ResearchObstetrics & Gynecology

Effectiveness of non-pharmacological interventions on stress and anxiety management in pregnancy: a systematic review.

This systematic review synthesized evidence on non-pharmacological approaches to preventing or managing stress, anxiety and fear of childbirth during pregnancy.

MidwiferyOct 4, 2026Read summary
Clinical ResearchGeriatricsOpen access

Should I drink water or wine? Impacts of online nutritional counseling on the alcohol consumption of elderly individuals with mild cognitive impairment : Secondary Data Analysis from the RCT "BrainFit-Nutrition".

This secondary data analysis from a randomized controlled trial evaluated the effects of nutritional counseling on alcohol consumption in 189 elderly individuals with mild cognitive impairment (MCI) over 12 months.

BMC Public HealthOct 3, 2026Read summary
Case ReportMedical Genetics

Androgen insensitivity syndrome: A case report.

A 29-year-old phenotypic female presented with primary amenorrhea and intermittent abdominal pain. Examination revealed normal breast development, sparse pubic hair, and female external genitalia.

Medicine (Baltimore)Oct 2, 2026Read case
Clinical ResearchPsychiatryOpen access

A Randomized Controlled Trial of a Digital Stepped-Care Program to Reduce Anxiety and Depressive Symptoms Among Long-Term Care Workers With Psychological Distress: The REPICAL Study.

The REPICAL study evaluated a digital stepped-care program aimed at reducing anxiety and depressive symptoms among long-term care workers (LTCWs) in Catalonia, Spain.

Depress AnxietyOct 2, 2026Read summary
Clinical ResearchPsychiatry

Attachment styles and problematic involvement in potentially addictive behaviours: A systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between attachment styles and problematic involvement in behaviours described as addictions, using peer-reviewed studies published before July 23rd, 2026.

Clin Psychol RevOct 2, 2026Read summary
Clinical ResearchNeurology

40 Hz transcutaneous auricular vagus nerve stimulation enhances verbal free recall in healthy adults by modulating frontal theta oscillations.

This randomized, single-blind, sham-controlled, three-arm trial examined whether 20 Hz or 40 Hz transcutaneous auricular vagus nerve stimulation (taVNS) affected verbal free recall and resting-state EEG theta activity…

NeuroimageOct 2, 2026Read summary
Clinical ResearchGeriatrics

Efficacy of immersive virtual reality reminiscence for older persons living in the community in Singapore: A multi-centre study.

This multicentre randomised controlled trial compared immersive virtual-reality reminiscence with photograph-based reminiscence in 60 community-dwelling older adults in Singapore (mean age 78.57 years).

Arch Gerontol GeriatrOct 2, 2026Read summary
Clinical ResearchPsychiatry

Irritability in the Mix: An Exploratory Study of the Role of Irritability in Characterising Mood Disorders.

This randomized controlled trial explored the relationship between irritability and mixed states in 82 patients with bipolar disorder over 18 months.

Bipolar DisordOct 1, 2026Read summary
Clinical ResearchPsychiatry

Bipolar Disorder and Perimenopause: An Update.

This systematic review examined the relationship between bipolar disorder (BD) and perimenopause, analyzing 14 studies from various countries.

Bipolar DisordOct 1, 2026Read summary
Case ReportPediatrics

A 6-Year-Old With Becker Muscular Dystrophy and Catatonia.

A 6-year-old boy presented with acute behavioral changes suggestive of catatonia, including altered speech and awareness. He was found to have previously undiagnosed Becker muscular dystrophy.

PediatricsOct 1, 2026Read case
Clinical ResearchPsychiatry

Quetiapine modestly improves sleep and breathing but impairs next-day performance in people with obstructive sleep apnea and difficulty maintaining sleep: a randomized controlled trial.

This randomized controlled trial evaluated the effects of 50 mg quetiapine versus placebo in 15 individuals with obstructive sleep apnea (OSA) and difficulty maintaining sleep.

Ann Am Thorac SocOct 1, 2026Read summary
Clinical ResearchPsychiatry

Negative affect influences the computations underlying food choice in bulimia nervosa.

This randomized controlled trial examined how negative affect influences food choice dynamics in 25 women with bulimia nervosa (BN) and 21 healthy controls.

ElifeOct 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Neural correlates of acute task-related stress in humans: a systematic review and coordinate-based ALE meta-analysis.

This systematic review and ALE meta-analysis examined the neural correlates of acute task-related stress using task-based fMRI studies.

Brain Imaging BehavOct 1, 2026Read summary
Clinical ResearchPsychiatry

Age- and sex-specific trends in Canadian mental health from 2003 to 2024: a repeated cross-sectional meta-regression analysis.

This meta-analysis examined trends in mental health outcomes in Canada from 2003 to 2024, using data from the Canadian Community Health Survey.

Epidemiol Psychiatr SciOct 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Psychoeducation for Youth at Clinical High-Risk of Psychosis.

This clinical trial evaluated the effects of psychoeducation on 54 youth at clinical high risk of psychosis. After 2-6 months, significant improvements were noted in attenuated psychotic symptoms, depression, and…

Early Interv PsychiatryOct 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Development and usability testing of a Spanish version of a mobile app-based adaptive coping skills intervention for critical illness survivors: Blueprint en español.

This multicenter clinical trial focused on adapting the Blueprint mobile app-based coping skills intervention for critical illness survivors to Spanish.

Ann Am Thorac SocOct 1, 2026Read summary
Clinical ResearchInfectious Diseases

Development of HOPES Intervention for a Randomized Controlled Trial to Reduce the Perceived Stigma Among Women Living With HIV/AIDS in China.

This study developed and pilot-tested HOPES, a culturally grounded WeChat program intended to reduce HIV-related stigma among Chinese women living with HIV/AIDS.

AIDS Educ PrevOct 1, 2026Read summary
Clinical ResearchOncology (Medical)

Digital health interventions for psychological and cognitive care in cancer patients and caregivers: A RE-AIM-based systematic review.

This PRISMA-guided systematic review assessed the internal and external validity of digital interventions for psychological and cognitive concerns among people with cancer, caregivers, and family members, using the…

Appl Psychol Health Well BeingOct 1, 2026Read summary
Clinical ResearchNeurology

Longitudinal clinical outcomes after amyloid clearance in aducanumab phase 3 studies.

This exploratory analysis pooled participants from the randomized phase 3 ENGAGE and EMERGE aducanumab trials who entered a long-term extension or later redosing study.

Alzheimers DementOct 1, 2026Read summary
Clinical ResearchGeriatrics

Prevalence and Predictors of Depressive Symptom Trajectories in Older Adults: A Systematic Review.

This systematic review examined longitudinal patterns of depressive symptoms and their predictors among adults aged 60 years or older.

Brain BehavOct 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis assessed randomised trials of psychological and psychosocial interventions targeting auditory hallucinations in adults with schizophrenia spectrum disorders.

JAMA PsychiatryOct 1, 2026Read summary
Clinical ResearchPsychiatry

Social Determinants of Health and Neurobiology Across the Schizophrenia Course: A Systematic Review.

This systematic review examined associations between adverse social determinants of health and brain measures in people across the schizophrenia spectrum, including those at elevated risk.

JAMA PsychiatryOct 1, 2026Read summary

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