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2000 articles
June 202624
Subcapsular versus total orchiectomy in advanced prostate cancer: A systematic review and meta-analysis of clinical and patient-reported outcomes.
This systematic review and meta-analysis evaluated clinical and patient-reported outcomes of subcapsular versus total orchiectomy in 759 men with advanced prostate cancer.
Hydrogel-based drug delivery systems for oral mucositis: a systematic review of preclinical models and translational perspectives.
This systematic review evaluated preclinical studies on hydrogel-based drug delivery systems for oral mucositis, a common complication of cancer therapies.
Clinical features, imaging findings, and treatment outcomes of optic neuritis associated with anti-CRMP5 antibodies: a systematic review.
This systematic review analyzed 32 patients with optic neuritis associated with anti-CRMP5 antibodies. The study found that 87.1% had bilateral optic neuritis, with 64% experiencing visual acuity worse than 20/200.
Perioperative Immunotherapy in Muscle-Invasive Bladder Cancer: A Systematic Review and Meta-Analysis of Neoadjuvant and Adjuvant Strategies.
This systematic review and meta-analysis evaluated the efficacy and safety of perioperative immunotherapy in muscle-invasive bladder cancer (MIBC) across 42 studies involving 6006 patients.
Upfront Total Mesorectal Excision for MRI-Defined Low-Risk cT3 Rectal Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis compared upfront total mesorectal excision (TME) with neoadjuvant therapy for MRI-defined low-risk cT3 rectal cancer. Five studies involving 1447 patients were included.
Osimertinib-Associated Benign Ocular Hyperpigmentation: A Case Report.
An Asian woman in her sixth decade with an 8-year history of non-small-cell lung cancer was found incidentally to have bilateral benign hyperpigmentation of the conjunctiva and corneal epithelium.
Comparison of [ 18 F]DCFPyL and [ 18 F]FAPI-74 PET/CT imaging in metastatic prostate cancer.
This prospective clinical trial compared the efficacy of PSMA-targeted [18F]DCFPyL and FAPI-targeted [18F]FAPI-74 PET/CT imaging in 39 patients with metastatic prostate cancer.
Cytological Diagnosis of Primary Cardiac Angiosarcoma Presenting With Multiple Serous Effusions: A Case Report With Cell Block.
A 42-year-old female presented with abdominal distension and exertional dyspnea, leading to the discovery of a cardiac space-occupying lesion and multiple serous effusions.
Dordaviprone Maintenance After Allogeneic HCT for High-Risk Acute Myeloid Leukemia and Myelodysplastic Neoplasm.
This Phase I clinical trial evaluated the safety of dordaviprone maintenance therapy after allogeneic hematopoietic cell transplantation in 20 adults with high-risk acute myeloid leukemia (AML) or myelodysplastic…
Quality assessment, prognostic factors, and biomarkers for brain tumor analysis: a comprehensive systematic review.
This systematic review examines the advancements in imaging technologies, prognostic factors, and biomarkers for brain tumors.
Malignant Perivascular Epithelioid Cell Tumor (PEComa) of Left Adrenal Gland With Extensive Intravenous Tumor Thrombi: 18 F-FDG PET/CT Findings.
A 53-year-old woman with left lower back pain, anemia, proteinuria, and hematuria was found to have bilateral adrenal masses on ultrasonography.
Atypical Presentation of Metastatic Prostate Adenocarcinoma in the Presacral Space: A Case Report of Diagnostic Resection via the Kraske Approach.
A 69-year-old man presented with hematuria and a 4-cm presacral mass, initially thought to be a primary neurogenic tumor based on MRI findings.
Artificial intelligence in genitourinary oncology: publication trends and systematic review.
This systematic review analyzed publication trends and randomized controlled trials (RCTs) regarding artificial intelligence (AI) in genitourinary oncology.
Myoepithelioma-like tumor of the vulvar region shows a quiet genome and heterogeneous detectable mechanisms of SMARCB1 inactivation: Integrated analysis of two cases and review of the literature.
Two cases of myoepithelioma-like tumor of the vulvar region (MELTVR) were analyzed, characterized by uniform epithelioid to spindle cells in myxoid stroma and complete loss of INI1 expression.
Long-Term Follow-Up of JCOG1008, a Randomized Phase II/III Trial of Chemoradiotherapy Comparing 3-Weekly Cisplatin With Weekly Cisplatin in Postoperative Head and Neck Cancer.
The JCOG1008 trial evaluated the long-term outcomes of chemoradiotherapy with weekly versus 3-weekly cisplatin in 261 patients with postoperative high-risk locally advanced squamous cell carcinoma of the head and neck.
Occult Pulmonary Adenosquamous Carcinoma Presenting With Synchronous Colonic Metastases.
A 60-year-old woman with a substantial smoking history and COPD presented with a refractory exacerbation, without a discrete lung parenchymal mass.
Distinct outcome patterns according to RAS and BRAF status in MSI-H/dMMR mCRC treated with immune checkpoint inhibitors: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of RAS and BRAF mutational status on outcomes in patients with MSI-H/dMMR metastatic colorectal cancer (mCRC) treated with immune checkpoint inhibitors…
Multi-ancestry genome-wide association meta-analysis of hepatocellular carcinoma identifies 15 risk loci including MAP3K9, DHRS1, MTTP, and 8q24.21.
This multi-ancestry genome-wide association meta-analysis examined germline susceptibility to all-cause hepatocellular carcinoma (HCC) across 15 cohorts, including 17,697 affected individuals and 2,715,683 controls.
Perineural invasion in intrahepatic cholangiocarcinoma: Meta-analysis of prevalence, association with tumor features, and impact on survival.
This meta-analysis evaluated the prevalence and prognostic significance of perineural invasion (PNI) in intrahepatic cholangiocarcinoma (ICC) across 61 studies involving 15,502 patients.
Cognitive impairments associated with meningiomas and gliomas in adults: A systematic review.
This systematic review examined cognitive impairments in adults with untreated meningiomas and gliomas, analyzing 70 studies involving 4,277 patients.
Nutritional Amino Acid Supplementation Reduces Severity and Enhances Recovery of Radiation-Induced Oral Mucositis: A Triple-Blind Randomized Clinical Trial.
This triple-blind randomized clinical trial evaluated the effects of oral L-arginine and L-glutamine supplementation on radiation-induced oral mucositis (RIOM) in 84 head and neck cancer patients.
Germline variants and impact on lung cancer outcomes following chemotherapy: A systematic review.
This systematic review examined the impact of germline genetic variants on chemotherapy outcomes in lung cancer patients of European ancestry.
Brief Report: Aumolertinib as a Switch Therapy in Osimertinib-Intolerant NSCLC-The ACTIVE Trial.
The ACTIVE trial was a prospective, multicentre, single-arm phase II study of aumolertinib as switch therapy for patients with EGFR-mutant advanced NSCLC who developed specified toxicities on osimertinib.
Two cases of durvalumab-induced Evans syndrome in biliary tract cancer.
Two men aged 71 and 73 with advanced hilar cholangiocarcinoma developed Evans syndrome while receiving durvalumab monotherapy after eight cycles of gemcitabine, cisplatin, and durvalumab.
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