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2000 articles

July 202624

Clinical ResearchOncology (Medical)Open access

Dose-reduced (24 Gy) involved-site radiotherapy combined with rituximab in early-stage non-gastric mucosa-associated lymphoid tissue lymphoma: a prospective phase II trial.

This prospective phase II trial evaluated the efficacy of 24 Gy involved-site radiotherapy combined with rituximab in 60 patients with early-stage non-gastric mucosa-associated lymphoid tissue lymphoma.

LeukemiaJul 16, 2026Read summary
Clinical ResearchOncology (Medical)

Pesticide exposure and all health outcomes: An umbrella review of meta-analyses of observational studies.

This umbrella review systematically analyzed 53 meta-analyses of observational studies to evaluate the health outcomes associated with pesticide exposure.

J Hazard MaterJul 16, 2026Read summary
Clinical ResearchHematologyOpen access

Asciminib monotherapy in patients with BCR::ABL1 T315I-mutated chronic-phase chronic myeloid leukemia: phase 1 trial final results.

This phase 1 trial evaluated the long-term safety and efficacy of asciminib in 48 patients with BCR::ABL1 T315I-mutated chronic-phase chronic myeloid leukemia (CML-CP).

LeukemiaJul 16, 2026Read summary
Clinical ResearchOncology (Medical)

Impacts of oncological treatments on fertility: A systematic review.

This systematic review evaluated the impact of oncological treatments on fertility using murine models, analyzing 30 studies.

Reprod ToxicolJul 16, 2026Read summary
Clinical ResearchOncology (Medical)Open access

A Prospective, Multicenter Randomized Controlled Trial (RCT) of the da Vinci SP ® Surgical System versus Open Surgery in Nipple-Sparing Mastectomy (NSM) Procedures for Patients with Breast Cancer.

This multicenter randomized controlled trial compared robotic-assisted nipple-sparing mastectomy (rNSM) using the da Vinci SP® system to open nipple-sparing mastectomy (NSM) in women with early-stage breast cancer.

Ann Surg OncolJul 16, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Thermal ablation versus liver resection for small colorectal liver metastases (≤ 3 cm): a systematic review and meta-analysis of randomized and propensity score-matched studies.

This systematic review and meta-analysis evaluated thermal ablation versus liver resection for small colorectal liver metastases (CRLM ≤ 3 cm) using data from seven studies.

Surg EndoscJul 16, 2026Read summary
Clinical ResearchOncology (Medical)

Direct tumour-adipocyte contact / Stroma AReactive Invasion Front Area (TAC/SARIFA) predicts adverse outcome in colorectal cancer: a focused evidence synthesis and meta-analysis.

This focused evidence synthesis and meta-analysis assessed whether direct tumour-adipocyte contact, termed TAC/SARIFA, is associated with survival in colorectal cancer.

HistopathologyJul 16, 2026Read summary
Clinical ResearchOncology (Medical)

Comparative analysis of patient-derived organoids and patient-derived xenografts as avatar models for predicting response to anti-cancer therapy.

This systematic review and meta-analysis compared patient-derived xenografts (PDX) and patient-derived organoids (PDO) in predicting treatment response in cancer patients.

Cancer Treat RevJul 16, 2026Read summary
Clinical ResearchHematology

Safety and efficacy of immune checkpoint inhibitors as a bridge to allogeneic hematopoietic stem cell transplantation in classical Hodgkin lymphoma: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the safety and efficacy of immune checkpoint inhibitors (ICIs) as a bridge to allogeneic hematopoietic stem cell transplantation (allo-HCT) in patients with classical…

Transpl ImmunolJul 16, 2026Read summary
Clinical ResearchGastroenterology

Comparison of long-term outcomes between liver transplantation and liver resection for intrahepatic cholangiocarcinoma: An updated systematic review and meta-analysis.

This systematic review and meta-analysis evaluated long-term outcomes of liver transplantation (LT) versus liver resection (LR) for intrahepatic cholangiocarcinoma (ICC) in 5478 patients.

Surg OncolJul 16, 2026Read summary
Clinical ResearchOncology (Medical)

Phase I Dose-Escalation Study Combining Irinotecan-Loaded Drug-Eluting Bead Chemoembolization with Yttrium-90 Glass Microsphere Radioembolization in Colorectal Liver Metastases (DEBIR 90 Y).

This Phase I dose-escalation study evaluated the maximum tolerated dose (MTD) of yttrium-90 glass microspheres combined with irinotecan-loaded drug-eluting beads in patients with colorectal liver metastases.

J Vasc Interv RadiolJul 16, 2026Read summary
Case ReportOphthalmology

Orbital Proptosis as the Sentinel Sign of Metastatic Desmoplastic Small Round Cell Tumor: A Rare Ophthalmic Gateway to Systemic Malignancy.

A 56-year-old man presented with 15 days of rapidly progressive, painless left proptosis. Examination showed axial proptosis and peripapillary flame-shaped hemorrhages.

Ann Afr MedJul 15, 2026Read case
Clinical ResearchEndocrinology

Immune checkpoint inhibitor-induced type 1 diabetes mellitus: incidence, risk factors, and prognostic implications - a systematic review and meta-analysis.

This systematic review and meta-analysis examined the incidence and risk factors of immune checkpoint inhibitor-induced type 1 diabetes mellitus (ICI-T1DM) in adult cancer patients.

Diabetes Res Clin PractJul 15, 2026Read summary
Case ReportOncology (Medical)Open access

HER2-positive rectal adenocarcinoma metastatic to the pancreas complicated by obstructive pancreatitis and an infected pseudocyst: a case report.

A man in his 60s presented with cerebellar masses; PET-CT also showed hypermetabolic lesions in the rectum and pancreas. Testing identified HER2-positive, RAS/BRAF wild-type rectal adenocarcinoma.

Clin J GastroenterolJul 15, 2026Read case
Case ReportDermatology

532-nm KTP Laser Treatment of Epidermal Growth Factor Receptor Inhibitor-Associated Paronychia: A Case Report.

A 67-year-old man with metastatic non-small cell lung cancer developed painful inflammation around multiple fingernails and both great toenails while receiving amivantamab.

Lasers Surg MedJul 15, 2026Read case
Clinical ResearchOncology (Medical)

Relationship between miRNAs dysregulation and the metastatic process associated with epithelial-mesenchymal transition in oral squamous cell carcinoma: A systematic review.

This systematic review evaluated the link between miRNA dysregulation and the metastatic process related to epithelial-mesenchymal transition (EMT) in oral squamous cell carcinoma (OSCC).

Arch Oral BiolJul 15, 2026Read summary
Clinical ResearchOncology (Medical)

Outcomes at rapid diagnostic centres and the association between non-specific symptoms and cancer: A systematic review and meta-analyses of up to 21,392 patients.

This systematic review and meta-analysis evaluated the association between non-specific symptoms (NSSs) and cancer in up to 21,392 patients diagnosed through rapid diagnostic centres.

Cancer EpidemiolJul 15, 2026Read summary
Case ReportOncology (Medical)

False-positive HIV-1 RNA detection after CAR-T cell therapy in a multiple myeloma patient: multi-assay comparison confirms dual-target cross-reactivity.

A patient with multiple myeloma undergoing CAR-T cell therapy tested positive for HIV-1 RNA using two dual-target assays, showing low copy numbers.

Diagn Microbiol Infect DisJul 15, 2026Read case
Clinical ResearchOncology (Medical)

An unanchored matching-adjusted indirect comparison of the efficacy of zanubrutinib versus ibrutinib for the treatment of relapsed/refractory mantle-cell lymphoma.

This study conducted an unanchored matching-adjusted indirect comparison to evaluate the efficacy of zanubrutinib versus ibrutinib in patients with relapsed/refractory mantle-cell lymphoma (R/R MCL).

J Med EconJul 14, 2026Read summary
Clinical ResearchOncology (Medical)

Efficacy of doxorubicin-loaded graphene nanoplatform chemo-photothermal therapy versus photothermal therapy alone for breast cancer xenograft tumors: a meta-analysis.

This meta-analysis evaluated the efficacy of doxorubicin-loaded graphene nanoplatform chemo-photothermal therapy (CPT) versus photothermal therapy (PTT) alone in breast cancer xenograft models.

Int J HyperthermiaJul 14, 2026Read summary
Clinical ResearchUrology

Network meta-analysis of immune checkpoint inhibitors in BCG-naïve, high-risk non-muscle-invasive bladder cancer.

This network meta-analysis evaluated the efficacy of immune checkpoint inhibitors (ICIs) combined with BCG in BCG-naïve high-risk non-muscle-invasive bladder cancer (NMIBC).

Urol OncolJul 14, 2026Read summary
Case ReportHematologyOpen access

Therapeutic drug monitoring guides personalized ponatinib dose reduction for chronic myeloid leukemia.

A 66-year-old woman with chronic-phase chronic myeloid leukemia was switched to ponatinib due to nilotinib-induced thrombocytopenia.

Int J HematolJul 14, 2026Read case
Clinical ResearchHematology

Impact of Hemoglobin Improvement on Survival in Patients With Myelofibrosis and Anemia Treated With Momelotinib in the SIMPLIFY-1 and MOMENTUM Trials.

These post hoc analyses of two phase 3 randomised trials examined how quickly patients with myelofibrosis and baseline hemoglobin < 10 g/dL achieved hemoglobin ≥ 10 g/dL with momelotinib, and whether this was associated…

Eur J HaematolJul 14, 2026Read summary
Clinical ResearchHematology

Clinical and Psychological Outcomes After Monoclonal Gammopathy Screening: A Population-Based Screening Study and Subsequent Randomized Trial of Follow-Up.

This nationwide Icelandic population-based screening study, which included a randomized trial of follow-up strategies, assessed clinical and psychological outcomes after monoclonal gammopathy screening.

J Clin OncolJul 14, 2026Read summary

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