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2000 articles
July 202624
Mandibular metastatic lung cancer: a rare case report with multimodal imaging.
A 67-year-old man presented with left mandibular pain, swelling, and gingival redness. Imaging revealed a mass-like radiopacity in the mandible without bone destruction.
A case of bone marrow-liver-spleen type diffuse large B-cell lymphoma: importance of rapid diagnosis and therapeutic intervention.
A 73-year-old woman presented with multiorgan failure and disseminated intravascular coagulation, raising concerns for secondary hemophagocytic lymphohistiocytosis.
Allogeneic hematopoietic stem cell transplantation achieves complete response in refractory primary mediastinal large B-cell lymphoma after the failure of chemotherapy, CAR-T therapy, and PD-1 blockade.
A 19-year-old female with refractory primary mediastinal large B-cell lymphoma (PMBCL) experienced a central nervous system relapse after partial response to chemotherapy.
AI Health message intervention: The role of message customization and message source in breast cancer screening among women of color.
This randomized controlled trial investigated the effectiveness of breast cancer screening messages with varying customization levels among women of color.
Symptom Networks and Core Symptoms in Patients with Solid Tumors Undergoing Chemotherapy: A Systematic Review.
This systematic review analyzed symptom networks in 13,452 adults with solid tumors undergoing chemotherapy. It identified fatigue as the most common core symptom, appearing in 50% of studies, and highlighted the…
Endobronchial Ultrasound-guided Diagnosis of Occult Lung Adenocarcinoma with Normal Chest Radiograph.
A 59-year-old woman with cough, hemoptysis, and dyspnea had an unremarkable chest radiograph despite persistent symptoms. HRCT showed abrupt cutoff of the left lower lobe bronchus with distal collapse, suggesting an…
Conversion surgery after BRAF-directed therapy for unresectable papillary thyroid carcinoma with severe tracheal invasion.
A 75-year-old man with locally advanced papillary thyroid carcinoma (PTC) presented with severe tracheal invasion and suspected carotid artery involvement, rendering the tumor initially unresectable.
Gastric atrophy and gastric cancer: a meta-analytical assessment of risk and the influence of topographical distribution.
This meta-analysis evaluated the risk of gastric cancer associated with gastric atrophy in 21,006 patients across ten studies.
Outcomes of Congenital Neuroblastoma With Placental Metastases: A Systematic Review.
This systematic review examined outcomes of congenital neuroblastoma with placental metastases, analyzing 16 articles and identifying 19 cases.
A High-Grade CD34-Positive Spindle Cell Sarcoma of the Palm Revealing an Unexpected TPM3::NTRK1 Fusion: A Diagnostic Pitfall With Major Therapeutic Implications.
A 17-year-old male presented with a rapidly enlarging palmar mass that recurred locally after excision. The tumor was first diagnosed as synovial sarcoma and later reinterpreted as fibrosarcomatous dermatofibrosarcoma…
Dynamic Circulating Tumor DNA Methylation Monitoring Guiding Postoperative Surveillance in Nonmetastatic Colorectal Cancer: A Prospective, Randomized, Phase III FIND Trial.
The prospective, multicenter, randomized phase III FIND trial compared circulating tumor DNA (ctDNA) methylation-guided surveillance with standard CT monitoring after curative resection of nonmetastatic colorectal…
Primed to feel, not to flare: Early life adversity and psychological sensitivity to interleukin-6 in a randomized trial among middle-aged female breast cancer survivors.
This randomized, placebo-controlled study examined whether early life adversity (ELA) altered inflammatory and psychological responses in 172 female breast cancer survivors.
FDG PET/CT in a Case of α-Fetoprotein-Producing Urothelial Carcinoma With Hepatoid Differentiation of the Renal Pelvis.
A patient presented with a tumor in the left renal pelvis that produced elevated serum alpha-fetoprotein levels (1035 ng/mL).
COMMIT: A Randomized Study of mFOLFOX6/Bevacizumab/Atezolizumab or Atezolizumab Alone as First-Line Treatment of Deficient DNA Mismatch Repair Metastatic Colorectal Cancer.
COMMIT was a multicentre, open-label, randomised phase III trial comparing first-line atezolizumab alone with mFOLFOX6/bevacizumab plus atezolizumab in patients with dMMR/MSI-H metastatic colorectal cancer.
Long-Term Clinical Outcomes of Tisagenlecleucel in Pediatric and Young Adult Patients With Relapsed/Refractory ALL.
This 5-year analysis of the global phase II ELIANA trial assessed long-term outcomes after a single tisagenlecleucel infusion in 79 children and young adults with relapsed or refractory B-cell acute lymphoblastic…
Immunophenotyping and Molecular Patterns of Prostate Cancer in East Africa: Diagnostic and Prognostic Implications-A Systematic Review.
This systematic review examined the immunophenotyping and molecular patterns of prostate cancer in East Africa, focusing on studies from Uganda, Sudan, Kenya, and Rwanda.
Patient and public involvement in the co-design of a multicenter randomized controlled trial on prehabilitation: results from the PREHAB-PEER conceptual phase.
This study focused on the co-design of a multicenter randomized controlled trial (RCT) for prehabilitation in colorectal cancer (CRC) patients.
Prognostic and predictive values of transcriptomic signatures in metastatic pancreatic cancer: A biomarker analysis of three French multicenter prospective randomized controlled phase 2 trials (Prodige35, Prodige37 and AFUGEM).
This study analyzed transcriptomic signatures in 178 patients with metastatic pancreatic cancer from three phase 2 trials. The immune classical subtype demonstrated superior median progression-free survival (PFS) of…
Evolutionary and resistance dynamics in oligometastatic and oligoprogressive cancer treated with stereotactic radiotherapy and systemic therapies: A systematic review and focused meta-analysis.
This systematic review and meta-analysis examined the evolutionary dynamics and resistance mechanisms in 1527 patients with oligometastatic and oligoprogressive cancer treated with stereotactic ablative radiotherapy…
When metabolic emergencies collide: A case of concurrent diabetic ketoacidosis and tumor lysis syndrome.
An 82-year-old man with extensive-stage small cell lung cancer presented to the emergency department five days after chemotherapy with symptoms including vomiting, hypotension, and tachypnea.
Symptom Clusters in Gastrointestinal Cancer Patients: A Systematic Review and Meta-Analysis of Their Association With Quality of Life.
This systematic review and meta-analysis synthesised 45 studies of symptom clusters in people with gastrointestinal cancer, examining cluster patterns, stability over time, and associations with quality of life.
Pediatric Synchronous Nasopharyngeal Carcinoma Mimicking Refractory Hodgkin Lymphoma.
A 12-year-old girl with a 5-month history of painless left neck swelling was diagnosed with nodular sclerosis classic Hodgkin lymphoma, stage II, on baseline histopathology and F-18 FDG PET-CT, respectively.
18 F-FAPI-04 PET/CT Reveals Thoracic Duct Tumor Infiltration Secondary to Gastric Cancer.
We report ¹⁸F-FAPI-04 PET/CT findings of thoracic duct infiltration by tumor in a 61‑year‑old man with advanced gastric adenocarcinoma. The patient underwent ¹⁸F-FDG PET/CT for initial staging.
Combined 177 Lu-FAP-2286 Therapy and Immunotherapy in Metastatic Esophageal Squamous Cell Carcinoma.
A 72-year-old man with low-to-moderate-grade esophageal squamous cell carcinoma, previously treated with surgery, radiotherapy, chemotherapy, and immunotherapy, presented with bilateral cervical lymph-node metastases.
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