Combined 177 Lu-FAP-2286 Therapy and Immunotherapy in Metastatic Esophageal Squamous Cell Carcinoma.

Clin Nucl MedJul 28, 2026 (epub)
Case ReportOncology (Medical)

Lixian Mou, Yemei Liu, Hongyu Yang et al.

✦ AI-curated · Sources linked

Case in brief

A 72-year-old man with low-to-moderate-grade esophageal squamous cell carcinoma, previously treated with surgery, radiotherapy, chemotherapy, and immunotherapy, presented with bilateral cervical lymph-node metastases. He was treated with two cycles of 177 Lu-FAP-2286 combined with camrelizumab. Follow-up imaging with 68 Ga-FAP-2286 PET/CT showed significant reduction of the metastatic lesions, and the treatment was well tolerated without severe adverse reactions.

Diagnostic / clinical pearl

This case highlights the potential of combining targeted radioligand therapy with immunotherapy in managing metastatic esophageal squamous cell carcinoma.

Source

PubMed · PMID 42530282

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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