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1303 articles

December 202511

Clinical ResearchPsychiatry

Stratified Stepped-Care for Reducing Suicide Attempts and Self-Harm in Youth: A Randomized Clinical Trial.

This randomized clinical trial evaluated whether adding stratified stepped-care for suicide prevention (SC-SP) to Zero Suicide quality improvement (ZSQI) reduced suicidal behavior among 301 youth aged 12–24 selected for…

J Am Acad Child Adolesc PsychiatryDec 23, 2025Read summary
Clinical ResearchGeriatrics

Evaluation of Non-Pharmacological Interventions for Community-Dwelling Individuals With Dementia Experiencing Sleep Disturbances: An Updated Systematic Review.

This updated systematic review examined randomised controlled trials of non-pharmacological interventions for sleep disturbances in community-dwelling people living with dementia.

J Appl GerontolDec 23, 2025Read summary
Clinical ResearchPsychiatryOpen access

Weapon or Armor? Unpacking the Paradox of Narcissism and Self-Reported Mental Health Through a Three-Level Meta-Analysis.

This three-level meta-analysis examined associations between dimensions of narcissism and mental health, particularly internalizing psychopathology.

J PersDec 22, 2025Read summary
Clinical ResearchPsychiatry

A systematic review and meta-analysis of routine white blood cell concentrations in people with eating disorders.

This systematic review and meta-analysis examined white blood cell (WBC) concentrations and subtypes in people with anorexia nervosa (AN) or bulimia nervosa (BN), compared with healthy controls, and during weight…

NeuroscienceDec 19, 2025Read summary
Clinical ResearchPsychiatryOpen access

Treatment outcomes of sexual minority women (SMW) veterans with military sexual trauma (MST).

This secondary analysis of a randomized clinical trial examined treatment outcomes among women veterans with military sexual trauma and posttraumatic stress disorder, comparing skills training in affective and…

Psychol TraumaDec 18, 2025Read summary
Clinical ResearchPsychiatry

The association between treatment integrity and treatment outcome of cognitive behavioural therapy for major depressive disorder.

This study examined whether treatment integrity—therapist adherence to and competence in cognitive behavioural therapy (CBT)—was associated with outcomes for major depressive disorder (MDD).

Cogn Behav TherDec 16, 2025Read summary
Clinical ResearchGastroenterologyOpen access

Efficacy and Safety of Auricular Acupressure for Insomnia in Patients With Functional Dyspepsia: A Randomized Controlled Trial.

This randomized controlled trial evaluated auricular acupressure (AA) for insomnia in patients with functional dyspepsia (FD), comparing treatment at the ear concha with sham acupressure at the earlobe.

Am J GastroenterolDec 10, 2025Read summary
Clinical ResearchPsychiatry

Can depression and anxiety apps improve quality of life, wellbeing, and disability outcomes? Meta-analysis of randomized controlled trials.

This meta-analysis of 25 randomized controlled trials assessed whether mental health apps for depression and anxiety improve quality of life, general wellbeing, and disability. Most trials focused on depression.

Cogn Behav TherDec 10, 2025Read summary
Clinical ResearchPsychiatry

Breakthroughs in emotional awareness: Exploring sudden gains in internet-based psychodynamic therapy for depressed adolescents.

This qualitative analysis explored processes surrounding sudden gains (SGs) during internet-delivered psychodynamic therapy (IPDT) for adolescent depression.

Psychother ResDec 8, 2025Read summary
Clinical ResearchPsychiatryOpen access

Domain-Specific Efficacy of Accelerated Repetitive Transcranial Magnetic Stimulation in Neuropsychiatric Disorders: A Systematic Review and Meta-Analysis.

This preregistered systematic review and random-effects meta-analysis assessed accelerated repetitive transcranial magnetic stimulation (arTMS; at least two sessions daily) versus sham in randomized trials across…

Biol PsychiatryDec 1, 2025Read summary
Clinical ResearchPsychiatry

Effectiveness of Trauma-Focused Interventions in Reducing Externalizing Behaviors Among Traumatized Adolescents: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined whether trauma-focused interventions reduce externalizing behaviors among traumatized adolescents.

Trauma Violence AbuseDec 1, 2025Read summary

November 202513

Clinical ResearchPreventive Medicine / Public Health

How Does Experience of Violence in Childhood Affect Work Outcomes? A Systematic Review of Longitudinal Studies.

This systematic review and narrative synthesis examined longitudinal evidence on childhood and adolescent violence and later work outcomes.

Trauma Violence AbuseNov 28, 2025Read summary
Clinical ResearchPsychiatry

Exploring early add-on celecoxib treatment in OCD: Results from a preliminary randomized, double-blind, placebo-controlled trial.

This preliminary randomized, double-blind, placebo-controlled trial evaluated celecoxib added early to fluoxetine in 44 drug-naive patients with obsessive-compulsive disorder over 8 weeks.

J PsychopharmacolNov 27, 2025Read summary
Clinical ResearchPsychiatryOpen access

Efficacy and Methodology of Remote Heart Rate Variability Biofeedback Interventions for Mental Health: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed remote heart rate variability biofeedback (HRV-B) for mental health symptoms and HRV across 18 studies involving 1,352 participants from different populations.

Appl Psychophysiol BiofeedbackNov 27, 2025Read summary
Clinical ResearchPsychiatryOpen access

Oral Methods of Microbiota Manipulation for Depression Symptoms: A Systematic Review: Méthodes orales de manipulation du microbiote pour traiter les symptômes de dépression : Une revue systématique.

This systematic review examined completed parallel-arm randomised controlled trials of oral microbiota manipulation and depressive symptoms in adults not taking antidepressants.

Can J PsychiatryNov 27, 2025Read summary
Clinical ResearchPsychiatry

Enhancing Emotion Regulation and Brain Connectivity in Adolescent Girls Through Parental Emotion Socialization: A Randomized Controlled Trial.

This randomized controlled trial tested whether an emotion-focused parenting intervention could affect emotion regulation and related brain connectivity in 10- to 12-year-old girls with elevated internalizing symptoms.

J Am Acad Child Adolesc PsychiatryNov 27, 2025Read summary
Clinical ResearchGeriatrics

Mental Health Outcomes Associated with Elder Abuse: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined quantitative studies of elder abuse and DSM-5-defined mental health outcomes in adults aged 60 years or older. It included 23 studies and 73 effect sizes.

Trauma Violence AbuseNov 27, 2025Read summary
Clinical ResearchPsychiatry

Implementation of a Face-To-Face Vs Virtual Peer-Integrated Collaborative Care Intervention for Mental Health Treatment of Physical Trauma Survivors: A Qualitative Study of Lessons from the COVID-19 Pandemic.

This qualitative study examined how the COVID-19 pandemic affected implementation of a peer-integrated collaborative care intervention for mental health among 450 patients receiving treatment for physical injuries.

PsychiatryNov 25, 2025Read summary
Clinical ResearchPsychiatry

Childhood Maltreatment and Its Long-Term Psychosocial Outcomes: An Umbrella Review of Meta-Analyses.

This umbrella review synthesized meta-analyses of childhood maltreatment and psychosocial outcomes, searching 11 databases through December 24, 2024.

Trauma Violence AbuseNov 24, 2025Read summary
Clinical ResearchPsychiatry

Effectiveness of Trauma-Focused Cognitive Behavioral Therapy for Youth with Complex Trauma Exposure: A Systematic Review.

This systematic review evaluated the effectiveness, feasibility, and acceptability of trauma-focused cognitive behavioral therapy (TF-CBT) for young people exposed to chronic, repeated, prolonged, interpersonal trauma.

Trauma Violence AbuseNov 24, 2025Read summary
Clinical ResearchPsychiatryOpen access

Examining the relationship between pre-treatment anhedonia and treatment outcomes in individuals with anxiety or depression: A systematic review.

This systematic review examined whether pre-treatment anhedonia or lower reward sensitivity was associated with outcomes of psychotherapy, pharmacotherapy, or neuromodulation in people with anxiety or unipolar…

J Affect DisordNov 21, 2025Read summary
Clinical ResearchPsychiatryOpen access

Frontal Cortex Stimulation Modulates Attentional Circuits and Increases Anxiety-Potentiated Startle in Anxious Depression.

This double-blinded, parallel randomized trial examined acute effects of transcranial direct current stimulation (tDCS) in 141 adults with major depressive disorder and elevated anxiety.

Biol Psychiatry Cogn Neurosci NeuroimagingNov 15, 2025Read summary
Clinical ResearchPreventive Medicine / Public Health

What Works in Reducing Economic Violence Against Women: Global Evidence From a Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed randomized controlled trials of interventions addressing economic violence against partnered women.

Trauma Violence AbuseNov 13, 2025Read summary
Clinical ResearchPsychiatry

Prevalence of Victimization Among Adults with Severe Mental Illness Worldwide: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined victimization prevalence and correlates among adults with severe mental illness in clinical samples.

Trauma Violence AbuseNov 12, 2025Read summary

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