The association between treatment integrity and treatment outcome of cognitive behavioural therapy for major depressive disorder.

Cogn Behav TherDec 16, 2025 (epub)
Clinical ResearchPsychiatry

N Zandstra, E Derksen, M F Miggiels et al.

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In 30 seconds

This study examined whether treatment integrity—therapist adherence to and competence in cognitive behavioural therapy (CBT)—was associated with outcomes for major depressive disorder (MDD). It was conducted within a pragmatic randomised non-inferiority trial comparing CBT with short-term psychodynamic supportive psychotherapy. Two sessions from each of 77 CBT cases were rated by independent assessors. Therapist competence, but not adherence, was significantly associated with treatment outcome; the association had a small effect size (ƒ² = 0.059). The findings suggest that how well therapists apply CBT techniques may matter more than strict protocol adherence.

Key findings

  • Therapist competence in CBT was significantly associated with treatment outcome, with a small effect size (ƒ² = 0.059).
  • Adherence to the CBT protocol was not significantly associated with treatment outcome.
  • The analysis included two randomly selected sessions from each of 77 CBT cases, rated by two independent assessors.

Why it matters

The findings highlight a distinction between delivering prescribed CBT components and applying them competently. For psychotherapy services, therapist skill may be a relevant factor when considering how to support treatment quality and outcomes. The observed association was small, however, and does not establish that increasing competence will cause better outcomes.

What to keep in mind

The analysis covered 77 CBT cases, with only two sessions rated per case; the reported association does not establish causality.

Source

Published in Cogn Behav Ther. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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