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1382 articles

May 202611

Clinical ResearchPediatricsOpen access

Incidence of Bacille Calmette-Guérin associated lymphadenitis in healthy children: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the incidence of Bacille Calmette-Guérin (BCG) lymphadenitis in healthy children, analyzing data from 52 studies involving approximately 1.8 million children.

Hum Vaccin ImmunotherMay 4, 2026Read summary
Clinical ResearchPediatrics

Effects of three different auditory interventions on physiological and behavioral responses to neonatal heel lance.

This randomized controlled trial evaluated the effects of white noise, classical music, and mother-sung lullabies on neonatal pain responses during heel lance in 100 newborns.

Early Hum DevMay 4, 2026Read summary
Clinical ResearchPediatricsOpen access

Global Pediatric Stroke Epidemiology: A Systematic Review of the Literature and Meta-Analysis.

This systematic review and meta-analysis assessed the global burden of pediatric stroke, revealing a birth prevalence of perinatal stroke at 21.01 per 100,000 total births and a childhood incidence of stroke at 3.73 per…

J Child NeurolMay 4, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Gestational Age-Specific Prevalence of Retinopathy of Prematurity in Very Preterm Infants: An Exploratory Meta-Analysis.

This meta-analysis evaluated the prevalence of Retinopathy of Prematurity (ROP) in very preterm infants, focusing on gestational age (GA) thresholds versus birth weight (BW) criteria.

Acta PaediatrMay 4, 2026Read summary
Case ReportInfectious DiseasesOpen access

Infliximab in a Child With Relapsing Tuberculous Meningoencephalitis: A Case Report and Literature Review.

A 5-year-old child with tuberculous meningoencephalitis experienced severe drug-induced hepatitis following standard antitubercular therapy, leading to the discontinuation of treatment.

Pediatr Infect Dis JMay 4, 2026Read case
Clinical ResearchPediatrics

Impact of Probiotics on Children with Acute Gastroenteritis: Results from an Umbrella Meta-Analysis.

This umbrella meta-analysis assessed probiotic efficacy for acute gastroenteritis in children, synthesising 36 meta-analyses with 107,541 participants.

J Integr Complement MedMay 4, 2026Read summary
Case ReportPlastic Surgery

PLANA Therapy for Infants With Bilateral Cleft Lip and Palate-Two Case Reports.

Two infants with bilateral cleft lip and palate received presurgical lip, nose alveolar approximation (PLANA) therapy; one had a mildly protruded premaxilla and the other a significantly protruded premaxilla.

Cleft Palate Craniofac JMay 4, 2026Read case
Clinical ResearchPediatrics

The effect of maternal scent-infused blanket on the stress level, crying duration and physiological parameters of premature newborns.

This randomized controlled trial assessed the impact of a maternal scent-infused blanket on stress levels, crying duration, and physiological parameters in 69 premature infants in the NICU.

J Matern Fetal Neonatal MedMay 3, 2026Read summary
Clinical ResearchNephrology

Renal osteodystrophy in pediatric patients. A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated histomorphometric findings in 980 bone biopsies from pediatric patients with chronic kidney disease (CKD).

BoneMay 2, 2026Read summary
Clinical ResearchPediatrics

Effects of Endotracheal Suctioning With Expiratory Pause in Infants.

This randomized controlled trial evaluated the effectiveness of closed endotracheal suctioning with an expiratory pause in infants on invasive mechanical ventilation.

Respir CareMay 2, 2026Read summary
Clinical ResearchPediatricsOpen access

Local application of otoprotective compounds other than sodium thiosulfate to prevent cisplatin-induced hearing loss: a systematic review.

This systematic review evaluated the efficacy and safety of locally applied otoprotective agents other than sodium thiosulfate (STS) to prevent cisplatin-induced hearing loss in pediatric cancer patients.

Drug DelivMay 1, 2026Read summary

April 202613

Clinical ResearchOphthalmology

Strabismus surgery outcomes in pediatric patients with developmental delay: a meta-analysis and systematic review.

This meta-analysis evaluated strabismus surgery outcomes in pediatric patients with developmental delays, comparing them to children without such delays. The analysis included 31 studies with 3687 subjects.

StrabismusApr 30, 2026Read summary
Clinical ResearchPediatrics

The Impact of Dosing Schedule on the Efficacy of Hand-Arm Bimanual Intensive Therapy Including the Lower Extremities (HABIT-ILE) in Children With Bilateral Cerebral Palsy.

This randomized controlled trial evaluated the efficacy of two dosing schedules of Hand-Arm Bimanual Intensive Therapy Including the Lower Extremities (HABIT-ILE) in 21 children aged 5 to 17 years with bilateral…

Neurorehabil Neural RepairApr 30, 2026Read summary
Clinical ResearchPediatricsOpen access

Improving oral health communication in paediatric dentistry using intraoral scanners: a multicentre pilot study.

This multicentre randomized controlled trial evaluated the effectiveness of intraoral scanners (IOS) in enhancing oral health communication among 60 children aged 6-14 and their caregivers.

Eur Arch Paediatr DentApr 29, 2026Read summary
Clinical ResearchPediatrics

Growth and human milk intake outcomes from postdischarge feedings among very-low-birth-weight preterm infants: A systematic review.

This systematic review evaluated the effects of postdischarge fortified human milk (HM) or breastfeeding with formula on growth and HM intake in very-low-birth-weight preterm infants.

Nutr Clin PractApr 29, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Effectiveness Comparison of Kinect-Based and Therapist-Based Bimanual Intensive Training in Children With Unilateral Cerebral Palsy: A Randomized Controlled Trial.

This randomized controlled trial compared Kinect-based bimanual intensive training (K-BIT) and therapist-based bimanual intensive training (T-BIT) in 31 children with unilateral cerebral palsy.

Arch Phys Med RehabilApr 28, 2026Read summary
Case ReportCardiology

Supracardiac Total Anomalous Pulmonary Venous Connection with Left Main Bronchial Compression in an Infant.

A 4-month-old male infant presented with supracardiac total anomalous pulmonary venous connection (TAPVC) and left main bronchial stenosis, alongside a central atrial septal defect and severe pulmonary hypertension.

World J Pediatr Congenit Heart SurgApr 28, 2026Read case
Clinical ResearchEndocrinology

Safety and Effectiveness of MiniMed TM 780G Advanced Hybrid Closed-Loop Use with Ultrarapid Insulin Lispro-AABC in Pediatric and Adult Type 1 Diabetes.

This 19-site, single-arm clinical trial evaluated MiniMed 780G advanced hybrid closed-loop use with ultrarapid insulin lispro-aabc (URLi) in children, adolescents, and adults with type 1 diabetes.

Diabetes Technol TherApr 28, 2026Read summary
Clinical ResearchPediatrics

Short-course Intravenous Antibiotic Therapy of Pediatric Acute Bone and Joint Infections: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the effectiveness of short-course intravenous antibiotic therapy (≤5 days) in previously healthy children with acute bone and joint infections (BJIs).

Pediatr Infect Dis JApr 27, 2026Read summary
Clinical ResearchOphthalmology

Optical coherence tomography measurements in retinopathy of prematurity: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated retinal and choroidal structural changes in individuals with a history of retinopathy of prematurity (ROP) compared to healthy controls.

Eur J OphthalmolApr 27, 2026Read summary
Case ReportMedical Genetics

Response of an Infant With Presumed Multiple Acyl-CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation.

An infant diagnosed with Multiple Acyl-CoA Dehydrogenase Deficiency (MADD) exhibited severe cardiac dysfunction. Despite genome sequencing failing to identify pathogenic variants, RNA sequencing indicated reduced ETFB…

Am J Med Genet AApr 27, 2026Read case
Clinical ResearchPediatrics

Clinical Evaluation of Pit and Fissure Sealants Placed by Intern Dental Students After Tele-Demonstration Technique.

This randomized controlled trial compared pit and fissure sealants placed by dental interns after direct clinical demonstration or tele-education using a pre-recorded video.

Eur J Dent EducApr 27, 2026Read summary
Clinical ResearchPsychiatry

Investigating inequalities in children and young people's mental healthcare and outcomes: prospective longitudinal analysis from the STADIA trial.

This prospective longitudinal analysis of data from the STADIA randomised controlled trial examined access to care and outcomes among 1,225 children aged 5–17 years referred to child and adolescent mental health…

Br J PsychiatryApr 27, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

When Rare Meets Young: Pediatric Presentation of Desmoplastic Fibroblastoma.

A 12-year-old boy presented with a 4.2 cm subcutaneous mass in the left thigh. Histologic examination showed a well-circumscribed proliferation of stellate and/or spindle-shaped fibroblasts in abundant, hypovascular…

Pediatr Dev PatholApr 26, 2026Read case

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