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2000 articles
October 202624
Neuronal intermediate filament neurologic autoimmunity in a patient with Merkel cell carcinoma receiving pembrolizumab.
A 55-year-old woman with recurrent stage IIIA Merkel cell carcinoma developed vertigo, gait instability, dysarthria, and persistent right hemifacial and cervical spasms after her second pembrolizumab dose.
Central retinal artery occlusion preceding hemispheric ischemic stroke treated with mechanical thrombectomy: A case report.
A 52-year-old man with dilated cardiomyopathy developed sudden, painless right-eye vision loss. Ophthalmologic examination and fluorescein angiography supported central retinal artery occlusion (CRAO).
Psychopathological and neuropsychological sequelae in children victimised by intimate partner violence: a clinical case series.
A clinical case series assessed four children aged 5–9 with documented exposure to intimate partner violence, including witnessing violence and, in some cases, direct abuse.
Primary tubal choriocarcinoma with extrauterine implantation masquerading as ectopic pregnancy: A case report and literature review.
A 29-year-old woman with irregular menses had extremely high β-human chorionic gonadotropin levels and ultrasonographic findings suggestive of ectopic pregnancy.
Staged limb salvage after an infected full-thickness shoulder-girdle flame burn with osteoarticular exposure in an elderly patient: A case report with 3.5-year follow-up.
A 73-year-old woman with diabetes, hypertension, and cachexia presented about 3 weeks after a flame burn with an extensive infected wound from the neck base to the distal left arm.
Neonatal nemaline myopathy associated with NEB variants and a favorable 3-year outcome: A case report.
A female neonate developed cyanosis, bradycardia, respiratory distress, and hypotonia shortly after birth, with recurrent respiratory deterioration and bulbar feeding and swallowing difficulties.
Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.
This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.
Primary renal diffuse large B cell lymphoma misdiagnosed as renal cell carcinoma: A case report.
A 78-year-old man presented with 2 weeks of right flank pain radiating to the abdomen; examination was unremarkable. Tests showed mildly elevated lactate dehydrogenase and occult blood in the urine.
Systematic review and meta-analysis of risk factors for oral frailty.
This systematic review and meta-analysis examined factors associated with oral frailty across 14 studies involving 12,297 participants, of whom 4,540 had oral frailty.
Comparative efficacy of common adjuvant treatments after resection of colorectal liver metastases: A systematic review and network meta-analysis.
This systematic review and network meta-analysis compared adjuvant strategies after resection of colorectal liver metastases, including systemic chemotherapy, hepatic arterial infusion chemotherapy (HAIC), and…
Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.
This prospective, single-arm, non-randomized phase Ib/II multicentre trial evaluated extracorporeal photopheresis (ECP) for steroid-refractory immune-related adverse events (irAEs) in 30 patients receiving immune…
A case report of thyroid sarcomatoid carcinoma.
A 65-year-old man presented with fever and left-sided neck pain; examination found a hard mass in the left thyroid lobe. Ultrasound showed a hypoechoic nodule with an anterior-posterior-to-transverse diameter ratio >1…
Spontaneous regression of post-traumatic syringomyelia: longitudinal mr imaging demonstrating a dynamic disease course.
A 69-year-old patient with post-traumatic cervicothoracic syringomyelia presented with occipital headaches, dizziness, and subjective upper-extremity weakness.
Precancerous cervical lesions and associated factors among HIV-positive women in Southern and Eastern African countries: A systematic review and meta-analysis.
This systematic review and meta-analysis pooled evidence on precancerous cervical lesions (PCCL) and associated factors among women living with HIV in Southern and Eastern Africa.
Intra-Arterial Alteplase After Successful Endovascular Reperfusion in Patients Without Intravenous Thrombolysis: A Subgroup Analysis of the PEARL Randomized Clinical Trial.
This prespecified subgroup analysis of the multicenter, randomized PEARL trial examined adjunctive intra-arterial alteplase after successful endovascular thrombectomy in patients with large-vessel occlusion stroke who…
The perceptions of hematopoietic stem cell transplantation decision-making in patients with hematologic malignancies: a qualitative systematic review.
This qualitative systematic review synthesized research on how patients with hematologic malignancies perceive decisions about hematopoietic stem cell transplantation (HSCT).
Search for the glycated hemoglobin target minimizing mortality among people with type 2 diabetes with rare incidence of treatment-related severe hypoglycemia - Epidemiologic analysis of J-DOIT3 randomized controlled trial.
This landmark analysis of the J-DOIT3 randomized controlled trial examined associations between updated HbA1c and cardiovascular outcomes or mortality among people with type 2 diabetes, in a setting where severe…
Efficacy and safety of GLP-1 receptor agonists in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH): A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed efficacy and safety of GLP-1 receptor agonists in adults with MASLD or MASH. Nine studies involving 795 participants were included.
Minocycline in acute stroke: A systematic review and meta-analysis of randomized controlled trials and trial sequential analysis.
This systematic review and meta-analysis pooled randomized controlled trials comparing minocycline with control or standard care in acute ischemic and hemorrhagic stroke.
Outcomes of Intra-Arterial Urokinase After Endovascular Reperfusion for Acute Ischemic Stroke Due to Cardioembolism: A Secondary Analysis of the POST-UK Trial.
This secondary analysis of the multicenter, randomized POST-UK trial assessed adjunctive intra-arterial urokinase after near-complete to complete reperfusion in patients with acute ischemic stroke due to cardioembolism.
Skeletal effects of GLP-1 receptor agonist therapy in adults with overweight or obesity: a systematic review.
This systematic review examined randomized evidence on bone mineral density (BMD) and bone-turnover markers in adults with overweight or obesity receiving GLP-1 receptor agonists.
Vulvar infection caused by Histoplasma capsulatum: case report and literature review.
A 38-year-old woman with advanced HIV infection presented with a vulvar lesion suggestive of carcinoma. Histopathology, fungal culture and molecular testing confirmed vulvar infection with Histoplasma capsulatum var.
Intermittent Maple Syrup Urine Disease Presenting With Chronic Demyelinating Polyneuropathy: A Genetically Confirmed DBT-Related Case.
A female patient with intermittent maple syrup urine disease (MSUD), genetically confirmed by compound heterozygous pathogenic DBT variants, had recurrent ataxic episodes from early childhood.
Impact of YAQ001 on the Gut Microbiome, Permeability and Markers of Systemic Inflammation in Patients With Cirrhosis.
This double-blind randomised controlled substudy examined YAQ001’s effects on the gut microbiome and exploratory markers of gut permeability and systemic inflammation in 28 patients with cirrhosis.
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