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1240 articles
May 202624
Eosinophilic vasculitis of aortic valve in EGPA: a life-threatening onset of disease.
A 51-year-old man with eosinophilic severe asthma and chronic rhinosinusitis presented with worsening dyspnea and cardiac arrest after two months of low-grade fever and malaise.
Progression of persistent atrial fibrillation and impact of ablation: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the progression of persistent atrial fibrillation (PsAF) to permanent atrial fibrillation (AF) in various populations.
Efficacy and safety of right neck phrenic nerve pacing in patients undergoing Cryoablation for atrial fibrillation.
This randomized controlled study used a within-patient crossover design to assess right phrenic nerve pacing from the neck versus the superior vena cava during cryoablation of right-sided pulmonary veins in 104 patients…
Direct His/LBB pacing as an alternative to biventricular pacing in patients with HFrEF and a typical LBBB: Design and rationale for the His-Alternative II trial.
The His-Alternative II trial is a multicenter, randomized non-inferiority study comparing conduction system pacing (CSP) to biventricular pacing (BiV-CRT) in patients with heart failure and left bundle branch block.
Superficial intercostal plane blocks for post-sternotomy pain control rationale and design for the EPOCH CardioLink-10 randomized clinical trial.
The EPOCH CardioLink-10 trial is a double-blind, placebo-controlled, multicenter randomized trial assessing the impact of continuous bilateral superficial parasternal intercostal plane (SPIP) blocks on opioid…
Safety, tolerability, pharmacokinetics, pharmacodynamics and food effect of HRS-1893, a cardiac myosin inhibitor, in healthy subjects.
This Phase I randomized controlled trial evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of HRS-1893, a cardiac myosin inhibitor, in healthy subjects.
Effects of Aerobic Exercise on Heart Rate Variability and C-Reactive Protein in Middle-Aged Adults With Normal Weight and Overweight/Obesity: A Pilot Study.
This controlled clinical trial investigated the effects of a 16-week aerobic exercise program on heart rate variability (HRV) and C-reactive protein (CRP) in middle-aged adults with normal weight and overweight/obesity.
Isolated cardiac metastasis after comprehensive treatment with hepatocellular carcinoma: a case report and literature review.
A 61-year-old male with BCLC-B stage hepatocellular carcinoma (HCC) underwent liver resection and subsequent treatments, including immunotherapy and radiofrequency ablation.
Accelerated Diagnostic Pathways for Suspected Acute Coronary Syndrome in Practice: A Randomized Trial of 0/1-Hour vs 0/3-Hour Troponin Testing.
This pragmatic randomized trial compared the 0/1-hour and 0/3-hour high-sensitivity troponin (hs-cTn) testing pathways for suspected acute coronary syndrome (ACS) in 3,543 patients across two emergency departments.
Age-related efficacy of aspirin in secondary prevention of coronary artery disease: START-ANTIPLATELET registry and meta-analysis of randomized trials.
This study examined whether age modifies aspirin’s efficacy for secondary prevention in coronary artery disease. It combined a multicentre prospective registry of patients hospitalized with acute coronary syndrome and…
Cost-effectiveness of catheter ablation in end-stage heart failure with atrial fibrillation: Insights from CASTLE-HTx.
The CASTLE-HTx trial evaluated the cost-effectiveness of catheter ablation combined with guideline-directed medical therapy (GDMT) versus medical therapy alone in 194 patients with end-stage heart failure and atrial…
Empiric and Trigger-Guided Superior Vena Cava Isolation in AF Ablation: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of empiric versus trigger-guided superior vena cava isolation (SVCI) in atrial fibrillation (AF) ablation.
Case Report: Fetal Congenital Right Atrial Appendage Aneurysm With 2-Year Postnatal Follow-Up.
A fetal congenital right atrial appendage aneurysm (RAAA) was diagnosed unusually early in the first trimester, with characteristic echocardiographic features showing a cystic structure connected to the right atrial…
Routine cerebral embolic protection during TAVR: A meta-analysis and trial sequential evidence from 11,000 randomized patients.
This updated meta-analysis pooled eight randomized controlled trials involving 11,692 patients undergoing transcatheter aortic valve replacement (TAVR) to assess routine cerebral embolic protection (CEP).
Serum chloride and the response to hydrochlorothiazide in patients with acute heart failure: a post-hoc analysis from the CLOROTIC trial.
This post-hoc analysis of the multicentre, randomised CLOROTIC trial examined whether baseline serum chloride modified the efficacy or safety of adding oral hydrochlorothiazide to intravenous furosemide in 230 patients…
Same-day discharge versus overnight stay after catheter ablation for atrial fibrillation: a systematic review and meta-analysis.
This systematic review and meta-analysis compared protocolized same-day discharge with overnight hospitalization after pulmonary vein isolation for atrial fibrillation in adults.
Direct oral anticoagulant monotherapy vs combination therapy with antiplatelets in chronic coronary syndrome patients with prior percutaneous coronary intervention requiring anticoagulation: A meta-analysis.
This meta-analysis of randomized trials evaluated the effects of direct oral anticoagulant (DOAC) monotherapy versus combination therapy with antiplatelets in chronic coronary syndrome patients post-percutaneous…
Body Awareness Therapy in Peripheral Arterial Disease: A Randomized Controlled Trial.
This randomized controlled trial evaluated the impact of body awareness therapy (BAT) combined with standard care on patients with peripheral arterial disease (PAD).
Infection of Cardiac Implantable Electronic Devices in Low and Middle Income Countries: A Systematic Review.
This systematic review synthesized 55 studies of cardiac implantable electronic device (CIED) infections in low- and middle-income countries, covering 96 448 device recipients.
Comparative efficacy of baroreflex activation therapy, cardiac contractility modulation, and cardiac resynchronization therapy in heart failure with reduced ejection fraction: a systematic review and network meta-analysis of randomized controlled trials.
This systematic review and network meta-analysis evaluated the efficacy of baroreflex activation therapy (BAT), cardiac contractility modulation (CCM), and cardiac resynchronization therapy (CRT) in adults with heart…
The effect of dietetic counseling combined with digital tools intervention on hemodynamic markers in Greek adults: The GATEKEEPER Study.
The GATEKEEPER Study, a randomized controlled trial, assessed the impact of dietetic counseling combined with digital tools on hemodynamic markers in 954 Greek adults aged ≥55 with cardiometabolic risk.
Type, severity, frequency and management of adverse reactions associated with ultrasound contrast agents: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence of adverse drug reactions (ADRs) associated with ultrasound contrast agents (UCAs) in over 1 million adults and 36,000 children.
Long-term cardiometabolic effects of early institutionalization and foster care: Evidence from the Bucharest Early Intervention Project.
This randomized controlled trial investigated the long-term cardiometabolic effects of early institutionalization and foster care in 139 young adults (mean age 22.6 years) from the Bucharest Early Intervention Project.
Confluent Vein-Like Structure Behind the Left Atrium in Late Gestation: A Case With False-Positive Suspicion of Anomalous Pulmonary Venous Connection.
A 34-year-old woman at 36 weeks of gestation underwent fetal echocardiography, revealing a tubular structure behind the left atrium, initially suggesting a confluent vein and raising concerns for pulmonary venous…
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