Trending archive
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1003 articles
February 20262
Evidence for the efficacy and safety of pre-exposure prophylaxis (PrEP) in all populations: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed PrEP efficacy and safety across populations, including studies published in English, Portuguese, or Spanish from 2018 to 2023.
Campylobacter fetus Bacteremia Presenting with Bilateral Lower Leg Cellulitis in an Immunocompetent Adult.
An 87-year-old woman without immunodeficiency presented with fever and pain in both legs. Examination showed inflammatory changes in both lower legs, and blood cultures grew Campylobacter fetus.
January 202618
Detection of Pseudomonas aeruginosa in cystic fibrosis after initiation of CFTR modulators: a systematic review.
This systematic review examined how Pseudomonas aeruginosa is detected in people with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor (ETI), including comparisons of culture and molecular methods.
GPR3 in neuro-metabolic-immune-reproductive nexus - a potential therapeutic target for Multi-System diseases.
This systematic review examined GPR3, an orphan G-protein-coupled receptor, across neurological, metabolic, immune, and reproductive systems, drawing on a literature search of PubMed and Web of Science.
Modeling of antibody waning after heterologous boosting with Ad5-nCoV in individuals primed with two-dose CoronaVac previously.
This analysis integrated longitudinal serological data from three randomized trials in Jiangsu, China, to model antibody waning after aerosolized or intramuscular Ad5-nCoV boosting in people primed with two doses of…
Clinical effectiveness and impact of 13-valent pneumococcal conjugate vaccines in preventing invasive pneumococcal disease among children with risk conditions: A systematic literature review.
This systematic literature review assessed PCV13 efficacy, effectiveness, and population impact for invasive pneumococcal disease (IPD) and all-cause pneumonia in children with immunocompromising or chronic medical risk…
Congenital babesiosis in China: first molecularly confirmed case of vertical transmission of Babesia microti .
A 74-day-old boy presented with fever, pallor, and severe haemolytic anaemia (haemoglobin 45 g/L). Peripheral blood smear showed ring forms and 16% parasitemia.
The efficacy and mechanism of an integrated mindfulness-based programme on posttraumatic stress disorder among people with HIV: a randomized controlled trial with 3-month follow up.
This randomized controlled trial evaluated an Integrated Mindfulness-Based Programme (IMBP), combining the Community Resiliency Model and mindfulness-based stress reduction, in 82 people with HIV and PTSD.
Global molecular epidemiology of Mycoplasma pneumoniae and its association with macrolide resistance and disease severity: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the global distribution of Mycoplasma pneumoniae genotypes and their associations with macrolide resistance and disease severity among infected patients.
Pneumatosis Cystoides Intestinalis Secondary to Antibiotic Therapy for Pulmonary Mycobacterium avium Complex Infection: A Case Report and Review of the Literature.
An 83-year-old woman receiving antibiotic therapy for pulmonary Mycobacterium avium complex infection developed pneumatosis cystoides intestinalis (PCI), characterized by gas within the gastrointestinal wall.
Cervico-vaginal Amoebiasis Masquerading as Malignancy-A Case Series Highlighting Rare Clinical Presentation of a Common Parasitic Infection.
Three women presented with lower genital tract lesions that appeared clinically and radiologically suspicious for malignancy.
Sustained salivary IgG but short-lived IgA responses following primary and booster MenACWY-TT vaccination in older adults.
This phase IV, open-label clinical trial assessed salivary antibody responses after primary MenACWY-TT vaccination in 216 adults aged 65–85 years; 100 participants received a booster one year later.
Case Report of an Uncommon Dermatologic Manifestation of Disseminated Stenotrophomonas Maltophilia Infection in a Patient With Aplastic Anemia.
An immunocompromised patient with aplastic anemia receiving antithymocyte globulin, cyclosporine, and methylprednisolone developed ecthyma gangrenosum associated with disseminated Stenotrophomonas maltophilia infection.
Epidemiological characteristics of rotavirus gastroenteritis in China: A systematic review of studies published from 2014 to 2023.
This systematic review analysed 320 studies published from 2014 to 2023 on rotavirus gastroenteritis (RVGE) incidence, population distribution and genotypes in China.
Immunogenicity and safety of 20-valent pneumococcal conjugate vaccine in pneumococcal vaccine-naive adults ≥18 years of age in India: A phase 3 single-arm trial.
This phase 3, multicenter, single-arm trial assessed immunogenicity and safety of one dose of 20-valent pneumococcal conjugate vaccine (PCV20) in pneumococcal vaccine-naive adults aged ≥18 years in India.
Andrographolide Sulfonate Injection for Adjunctive Treatment of Non-severe Community-Acquired Pneumonia in Adults: A Multicenter, Double-Blind, Randomized Controlled Trial.
This multicenter, double-blind, placebo-controlled randomized trial evaluated adjunctive andrographolide sulfonate (AS) injection in adults hospitalized with non-severe community-acquired pneumonia receiving standard…
Unmasking a B-Cell Linkage Phenotype in Severe Acute Meningoencephalitis: A Case Report of IVIG and HydroBox-assisted Immunomodulatory Therapy.
A previously healthy 30-year-old man developed fulminant acute meningoencephalitis with coma, respiratory failure, and severe systemic inflammation.
Emergency department-initiated buprenorphine vs brief intervention for opioid use disorder: a systematic review and meta-analysis of clinical trials.
This systematic review and meta-analysis pooled randomized and nonrandomized clinical trials comparing emergency department (ED)-initiated buprenorphine with brief intervention, referral, or usual care for opioid use…
Effectiveness of Quality Improvement Strategies in Preventing Healthcare-Associated Infections Among Neurosurgical Patients Admitted to Intensive Care Units: A Systematic Review.
This systematic review evaluated quality improvement (QI) interventions to prevent healthcare-associated infections among neurosurgical and neurological ICU patients.
Efficacy and Safety of Tegoprazan-Containing Versus Proton Pump Inhibitor-Containing Regimens for First Line Helicobacter pylori Eradication-An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This updated systematic review and meta-analysis compared tegoprazan-containing with proton pump inhibitor (PPI)-containing first-line regimens for Helicobacter pylori eradication in treatment-naïve adults.
December 20254
Outbreak of Klebsiella aerogenes in a neurosurgical department linked to contaminated shampoo equipment from an outsourced barber department: A threat to infection control in outsourced healthcare services.
Outsourced hospital services may pose underrecognized risks for healthcare-associated infections, particularly in high-risk areas such as neurosurgery.
Sustained Virologic Response Following a Shortened Course of Direct-Acting Antiviral Therapy in an HIV/HCV Co-Infected Patient With Previous Treatment Experience: A Case Report.
A 47-year-old treatment-experienced man with HIV and chronic HCV had completed 10 weeks of sofosbuvir-velpatasvir before starting sofosbuvir-velpatasvir-voxilaprevir.
Novel de novo CLCN7 mutation in refractory osteopetrosis-related osteomyelitis: A case report and multidisciplinary therapeutic dilemmas.
A 57-year-old man with ADO-II presented with refractory mandibular osteomyelitis, facial swelling, and trismus. Imaging showed mandibular osteolysis alongside “sandwich vertebrae” and “Erlenmeyer flask” deformities…
Successful remdesivir treatment of coronavirus OC43 pneumonia in a lung transplant recipient.
A 60-year-old man with a bilateral lung transplant presented with worsening dyspnea and dry cough. Room-air arterial blood gas analysis showed respiratory failure.
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