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1320 articles
July 202624
Progressive Parkinsonism in PPP2R5D-Related Neurodevelopmental Disorder.
PPP2R5D-related neurodevelopmental disorder (Houge-Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy.
A Multimodal Assessment of Gastric Motility, Reflux Risk, and Clinical Efficacy: Intermittent Oro-Esophageal Versus Nasogastric Tube Feeding for Poststroke Dysphagia in a Randomized Controlled Trial.
This prospective, single-centre randomized controlled trial compared intermittent oro-esophageal (IOE) with nasogastric (NG) tube feeding in 54 adults with poststroke dysphagia, alongside standardized swallowing…
Comparison of Cranial Ultrasound and Amplitude-Integrated Electroencephalography in Predicting Neurodevelopmental Outcomes in Neonates With Hypoxic-Ischemic Encephalopathy: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed how amplitude-integrated electroencephalography (aEEG) and cranial ultrasound (cUS) predict neurodevelopmental outcomes in term and near-term neonates with…
Effects of concurrent transcranial direct current stimulation on human motor skill learning: A systematic review and Bayesian meta-analysis.
This systematic review and Bayesian meta-analysis examined the effects of concurrent transcranial direct current stimulation (tDCS) on motor skill learning across 73 studies.
Phase III Open-Label, Randomized Clinical Trial of Epidermal Growth Factor and Growth Hormone Releasing Hexapeptide in Acute Ischemic Stroke.
The COURAGE-2 study was a multicenter, randomized, open-label phase III trial assessing the efficacy of intravenous Epidermal Growth Factor (75µg) and Growth Hormone Releasing Peptide-6 (5mg) in patients with acute…
Pesticide exposure and all health outcomes: An umbrella review of meta-analyses of observational studies.
This umbrella review systematically analyzed 53 meta-analyses of observational studies to evaluate the health outcomes associated with pesticide exposure.
Ischemic Postconditioning in Patients With Acute Stroke With Successful Recanalization After Endovascular Therapy: A Pilot Randomized Controlled Trial.
This pilot randomized controlled trial investigated the effect of ischemic postconditioning (IPostC) on infarct growth in 60 patients with acute ischemic stroke who achieved successful recanalization after endovascular…
Comparison of the Effects of Telerehabilitation-Based Motor and Cognitive Dual-Task Exercises in Patients With Parkinson's Disease-A Randomized Controlled Study.
This randomized controlled trial evaluated the effects of telerehabilitation-based motor-motor and cognitive-motor dual-task training in 30 patients with Parkinson's disease.
Coexisting Inflammatory and Hereditary Neuropathies: A Review.
This review presents two patients with both chronic inflammatory demyelinating polyneuropathy (CIDP) and Charcot-Marie-Tooth disease type 1A (CMT1A), alongside a review of reported overlap cases involving CMT1A, CMT1B…
Neuropsychiatric adverse events with anti-seizure medications in patients with epilepsy: A systematic review and meta-analysis.
This systematic review and meta-analysis synthesized observational evidence on neuropsychiatric adverse events (NPAEs) associated with anti-seizure medications (ASMs) in people with epilepsy.
Diffuse cranial vault hyperostosis associated with long-term antiepileptic therapy: Autopsy findings and differential diagnostic considerations.
A 53-year-old woman with longstanding epilepsy treated with phenytoin and sodium valproate collapsed and died despite resuscitation.
Adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and longitudinal changes in global cognition: a post hoc analysis of the MIND trial.
This post hoc analysis of the MIND trial evaluated the relationship between adherence to the MIND diet and changes in global cognition among 590 community-dwelling adults aged 65 to 84.
Effect of intravenous tirofiban on the radiologic classification of intracranial hemorrhage after endovascular treatment in acute anterior circulation occlusive stroke: results from the RESCUE BT trial.
This randomized controlled trial from the RESCUE BT study evaluated the impact of intravenous tirofiban on intracranial hemorrhage (ICH) subtypes in 945 patients undergoing endovascular treatment for acute anterior…
Brain abscess formation following cerebral infarction during treatment for hypervirulent Klebsiella pneumoniae meningoencephalitis: A case report.
A patient with rapidly progressive meningoencephalitis due to hypervirulent Klebsiella pneumoniae developed cerebral infarction and subsequent brain abscess formation during treatment.
Heterozygous RNF13 Truncating Variants Are Associated With Developmental and Epileptic Encephalopathy.
The report describes 13 additional individuals with developmental and epileptic encephalopathy 73 associated with RNF13 variants: two had missense variants and 11 had truncating variants.
Novel Homozygous Mitochondrial Calcium Uptake Protein 1 Variant (c.38T>C, p.Leu13Pro) in a 7-year-old Girl with Congenital Ptosis and Proximal Myopathy: Expanding the Phenotypic Spectrum.
A 7-year-old Indian girl presented with global developmental delay, congenital nonfatigable right ptosis, and proximal-predominant myopathy without calf hypertrophy.
Optimizing brain functional-structural architecture with cTBS to reduce relapse in alcohol use disorder: a randomized controlled trial.
This randomized, double-blind, sham-controlled trial evaluated right dorsolateral prefrontal cortex continuous theta-burst stimulation (cTBS) in 50 adults with alcohol use disorder.
Claudin-11-Mediated Hypomyelinating Leukodystrophy 22: New Insights Into Pathogenic Mechanisms.
A child presented with global developmental delay, hypotonia, limb hypertonia, esotropia, and absence of early milestones, later showing partial motor improvement but persistent cognitive impairment.
Magnolol as a promising multitarget agent for Alzheimer's disease: Evidence from a systematic evidence synthesis, network pharmacology, and molecular dynamics simulations.
This systematic review evaluated the therapeutic effects of magnolol (MN) in preclinical Alzheimer's disease models, integrating network pharmacology and molecular dynamics simulations.
Mineralizing Angiopathy as a Rare Etiology of Pediatric Stroke: Report of Three Cases.
Three infants aged 14 to 38 months presented with basal ganglia infarction following minor head trauma. Neuroimaging revealed lenticulostriate calcifications, confirming a diagnosis of mineralizing angiopathy.
Lesion-induced hemichorea-ballism: A systematic review of 586 cases.
This systematic review examined clinical features and lesion locations in 586 published cases of lesion-induced hemichorea-ballism identified through January 2025.
A systematic review of highly purified cannabidiol in developmental and epileptic encephalopathies and complex treatment-resistant epilepsies: Nonseizure outcomes.
This systematic literature review assessed nonseizure outcomes after highly purified cannabidiol (CBD) initiation in people with developmental and epileptic encephalopathies or complex treatment-resistant epilepsies…
Delineating the epilepsy phenotype of ring chromosome 20: A systematic literature review.
This systematic literature review examined epilepsy features and outcomes in people with ring chromosome 20, drawing on 71 studies and 192 patients.
Urinary Biomarkers for Screening High-Risk Urodynamic Phenotypes in Early Spinal Cord Injury: A Pilot Study.
This prospective cohort pilot study assessed whether urinary biomarkers could identify adverse urodynamic phenotypes early after spinal cord injury.
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