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2000 articles
September 202624
EuroNet-PHL-LP1: complete resection or low-dose chemotherapy for pediatric low-risk nodular lymphocyte-predominant Hodgkin lymphoma.
The EuroNet-PHL-LP1 trial evaluated treatment strategies for pediatric patients with early-stage nodular lymphocyte-predominant Hodgkin lymphoma (nLPHL).
Circulating tumor DNA and recurrence after curative-intent treatment of hepatocellular carcinoma: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether circulating tumor DNA (ctDNA) detection predicts outcomes after curative-intent treatment for hepatocellular carcinoma.
DSM-TACE Versus Conventional Approaches in HCC: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis compared degradable starch microsphere transarterial chemoembolization (DSM-TACE) with conventional TACE or drug-eluting bead TACE in patients with hepatocellular carcinoma.
Indwelling pleural catheter enabling safe air travel in malignant pleural effusion with pneumothorax ex vacuo.
A man with pleural mesothelioma developed a large left hydropneumothorax after drainage of malignant pleural effusion. An indwelling pleural catheter was placed, allowing for management of symptoms and the risk of air…
Single-fraction stereotactic radiosurgery vs. hypofractionated stereotactic radiotherapy for resected brain metastases: a systematic review and meta-analysis of comparative studies.
This systematic review and meta-analysis evaluated the effectiveness of single-fraction stereotactic radiosurgery (SF-SRS) versus hypofractionated stereotactic radiotherapy (HF-SRT) in adults with resected brain…
Cardiac metastases from colorectal cancer: a comprehensive systematic review of clinical presentation, cardiac involvement, and outcomes.
Cardiac metastasis from colorectal cancer (CRC) is exceedingly rare and remains poorly defined in the literature. As survival improves and metastatic patterns evolve, recognizing the clinical and anatomical…
The effect of a smartphone-based educational intervention on the supportive care needs of family caregivers of patients with colorectal cancer: a randomized controlled trial.
This randomized controlled trial evaluated the impact of a smartphone-based educational program on the supportive care needs of family caregivers of colorectal cancer patients.
Osimertinib Plus Platinum-based Chemotherapy in Patients With EGFR-Mutated Advanced NSCLC Post-progression on First-Line Osimertinib: ORCHARD.
ORCHARD was a biomarker-directed, phase II platform study evaluating osimertinib plus platinum-based chemotherapy in patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC) after progression on first-line…
First-in-Human Study of the PARP Inhibitor HWH340 in Advanced Solid Tumors with Enrichment for Homologous Recombination Repair Gene Mutations.
This Phase I, open-label, multicenter trial evaluated the safety and preliminary efficacy of the PARP inhibitor HWH340 in patients with advanced solid tumors, particularly those with homologous recombination repair gene…
Clinical Relevance of Post-Treatment Circulating Tumor DNA Detection in Early Breast Cancer Using a Tissue-Free Epigenomic Assay: A 2-Year Landmark Analysis.
This phase III clinical trial evaluated the prognostic value of post-treatment circulating tumor DNA (ctDNA) detection in 313 patients with early-stage breast cancer.
Posttherapy [ 18 F]FDOPA PET Findings in an Anaplastic Pleomorphic Xanthoastrocytoma With a BRAF V600E Mutation.
A 10-year-old boy with a left temporal anaplastic pleomorphic xanthoastrocytoma (APXA) carrying a BRAF V600E mutation presented with generalized tonic-clonic seizures occurring 3–4 times weekly.
Discordant ¹⁸F-FDG and ⁶⁸Ga-DOTATATE PET/CT Findings Before Radionuclide Therapy in Small Cell Lung Cancer.
A 54-year-old man with progressive small cell lung cancer underwent ¹⁸F-FDG and ⁶⁸Ga-DOTATATE PET/CT assessment before radionuclide therapy.
Surgical outcomes of appendiceal mucinous neoplasms: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed surgical outcomes for appendiceal mucinous neoplasms, drawing on 43 observational cohort studies involving 12,014 patients.
Pulmonary nocardiosis following pembrolizumab use: case report and literature review of nocardiosis associated with immune checkpoint inhibitors.
A woman in her 80s with biliary tract cancer previously treated with pembrolizumab was taking low-dose corticosteroids for immune-related nephritis and hepatitis.
An integrated lifestyle intervention for mitigation of adverse effects associated with androgen deprivation therapy for prostate cancer (STAMINA): a multicentre, randomised trial.
The STAMINA trial, a multicentre, randomised study, evaluated a lifestyle intervention for men undergoing androgen deprivation therapy (ADT) for prostate cancer.
Sequential 18 F-FDG and 68 Ga-FAPI-04 PET/CT in Early Peritoneal Recurrence of Signet-Ring-Component Rectal Adenocarcinoma.
A 60-year-old man with poorly differentiated rectal adenocarcinoma containing a signet-ring component developed biochemical progression after multimodal treatment.
Gastric perforation repaired by hepatic round ligament: Case report and literature review.
A 44-year-old male with advanced gastric adenocarcinoma and peritoneal carcinomatosis presented with acute abdomen after stent insertion. Imaging confirmed gastric perforation and generalized peritonitis.
A systematic review and network meta-analysis of single nucleotide polymorphisms associated with oral submucous fibrosis risk.
This systematic review and network meta-analysis evaluated the association between single nucleotide polymorphisms (SNPs) and the risk of oral submucous fibrosis (OSF) in a population of 2545 cases and 3772 controls.
High-grade B-cell lymphoma presenting with bulbar palsy and Tapia syndrome: A case report.
A 46-year-old male presented with dysphagia, which led to the diagnosis of high-grade B-cell lymphoma. His symptoms included bulbar palsy and Tapia syndrome, which are uncommon initial manifestations of lymphoma.
Evaluating the potential of candidate surrogate endpoints for overall survival in treatment-naive metastatic melanoma treated with anti-PD-1-based regimens with or without anti-CTLA-4 therapy.
This meta-analysis evaluated potential surrogate endpoints for overall survival (OS) in 1865 treatment-naive metastatic melanoma patients receiving anti-PD-1 regimens.
Synthetic long peptide and DNA personalized cancer vaccines induce robust neoantigen-specific T cell responses in pancreatic cancer.
This phase I clinical trial evaluated the safety and immunogenicity of synthetic long peptide and DNA personalized cancer vaccines in patients with resected pancreatic ductal adenocarcinoma.
Artificial Intelligence for Diagnosis, Risk Stratification, and Prognosis of Neuroblastoma - A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the performance of artificial intelligence (AI) in diagnosing, risk stratifying, and prognosing neuroblastoma across 53 studies.
Neoadjuvant combined immunotherapy with intratumoral TransCon TLR7/8 Agonist and systemic TransCon IL-2 β/y or pembrolizumab in patients with locally advanced oral cancer-a monocentric experience.
Combination immunotherapy has shown encouraging activity across multiple solid tumors. We report the complete and consecutive cohort of patients with locally advanced oral squamous cell carcinoma (OSCC) treated at a…
Unexpected ¹⁸F-DOPA Uptake in Pediatric Posterior Mediastinal Ewing Sarcoma: A Diagnostic Pitfall in Pediatric Oncology.
A pediatric patient with posterior mediastinal Ewing sarcoma had an unexpected finding on ¹⁸F-DOPA PET/CT: the tumor showed tracer uptake.
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