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937 articles
April 202624
Consolidative Camrelizumab Following Definitive Concurrent Chemoradiation Therapy With Involved-Field Irradiation in Locally Advanced Esophageal Squamous Cell Carcinoma: A Single-Arm Phase 2 Trial.
This single-arm phase 2 trial evaluated the efficacy of camrelizumab consolidation therapy in 32 patients with unresectable locally advanced esophageal squamous cell carcinoma (ESCC) following definitive concurrent…
Safety and extrapulmonary effects of elexacaftor-tezacaftor-ivacaftor in people with cystic fibrosis following lung transplantation: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the safety and efficacy of elexacaftor-tezacaftor-ivacaftor in 195 cystic fibrosis patients post-lung transplantation.
Multidisciplinary Management of Metastatic Pancreatic Neuroendocrine Tumor Using a Combination of Beta, Alpha Radionuclide and Ethanol Ablation Therapies.
A young patient with metastatic pancreatic neuroendocrine tumor underwent peptide receptor radionuclide therapy (PRRT) using beta and alpha radionuclides.
Endoscopic Surveillance in Serrated Polyposis Syndrome, Two or Three-Year Intervals: A Non-inferiority Randomized Trial.
This multicenter, randomized non-inferiority trial evaluated the incidence of advanced neoplasia in patients with serrated polyposis syndrome undergoing colonoscopy surveillance at two- versus three-year intervals.
Cutaneous Manifestation of Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma: A Clue to A Gastrointestinal Malignancy.
A 68-year-old man presented with multiple purpuric patches from his axilla to groin, leading to a diagnosis of primary cutaneous cytotoxic T-cell lymphoma after skin biopsy.
Effect of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on Male Sexual Function: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effects of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) on male sexual function in 848 patients.
Patient Preferences, Perceptions, and Influencing Factors in Weight Loss Pharmacotherapy and Bariatric Surgery: A Systematic Literature Review.
This systematic review analyzed patient preferences regarding weight loss pharmacotherapy and bariatric surgery among adults with overweight or obesity.
Beyond Sarcopenia: A Systematic Review and Meta-Analysis on Muscle Outcomes After Bariatric Surgery.
This systematic review and meta-analysis examined longitudinal and cross-sectional evidence on muscle quantity, strength, and physical performance after metabolic and bariatric surgery, excluding studies with…
Linked-color imaging with computer-aided detection and the proximal adenoma miss rate: a randomized tandem trial.
This randomized controlled trial evaluated the effectiveness of linked-color imaging (LCI) with computer-aided detection (CADe) in reducing adenoma miss rates during colonoscopy.
Re-establishing bile acid composition after treatment of recurrent Clostridioides difficile infection with fecal microbiota transplantation compared with oral vancomycin or a 12-strain bacterial mixture.
This randomized controlled trial examined bile acid composition in patients with recurrent Clostridioides difficile infection treated with fecal microbiota transplantation (FMT), a bacterial mixture, or vancomycin.
Endoscopic mucosal resection with precutting vs. anchoring technique using snare tip for 10-25 mm nonpedunculated colorectal polyps: a randomized controlled trial.
This randomized controlled trial compared precutting EMR (P-EMR) and anchoring EMR (A-EMR) techniques for resecting nonpedunculated colorectal polyps sized 10-25 mm.
Patatin-Like Phospholipase Domain-Containing Protein 3 rs2896019 and MASLD Susceptibility and Severity in Adults: A Systematic Review and Meta-Analysis of Case-Control Studies.
This systematic review and meta-analysis examined the association between the PNPLA3 rs2896019 polymorphism and metabolic dysfunction-associated steatotic liver disease (MASLD) in adults.
Emergence of KPC-producing hypervirulent Klebsiella pneumoniae in a case of fatal recrudescent liver abscess.
A 76-year-old man with pancreatic cancer developed septic shock from a recurrent liver abscess after a four-week course of cefepime.
Effects of race distance and probiotics intervention on kidney, muscle, and gut injury and inflammation biomarker responses during running.
This randomized, double-blind, placebo-controlled study examined kidney, muscle, and gut inflammation biomarkers in 34 participants completing 42 trail races of 20–164 km, and assessed whether four weeks of…
Efficacy of Biological and Steroid Therapies in Adolescent and Adult Patients With Eosinophilic Esophagitis: A Systematic Review and Network Meta-Analysis With Meta-Regression.
This systematic review and network meta-analysis compared pharmacological treatments for eosinophilic esophagitis in participants aged 12 years or older, using 13 randomized controlled trials.
Malignancy in Long-Standing Perianal Fistulizing Crohn's Disease: Too Little, Too Late.
A 71-year-old man with nearly 50 years of untreated perianal fistulizing Crohn’s disease had recurrent abscesses, sepsis, and fistulizing disease.
Sphingosine 1-Phosphate (S1P) Receptor Modulators as an Induction and Maintenance Therapy for Moderate to Severe Ulcerative Colitis: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis pooled eight randomized controlled trials involving 2663 adults with ulcerative colitis, comparing sphingosine-1-phosphate receptor modulators with placebo.
Red cell distribution width as a prognostic predictor for colorectal cancer: a meta-analysis.
This meta-analysis assessed whether preoperative red cell distribution width (RDW) predicts postoperative survival in people with colorectal cancer (CRC). It included 16 studies involving 20,500 individuals.
Successful initiation of fully parenteral antiretroviral therapy in a treatment-naïve person with HIV-1 infection and intestinal failure.
A 26-year-old man with newly diagnosed HIV-1 infection developed fulminant necrotizing pancreatitis, multiple surgical complications, short bowel syndrome, and intestinal failure with no gastrointestinal passage.
Metastatic carcinomatous cirrhosis from diffuse breast cancer liver metastasis: a case report.
A woman in her 50s with a history of breast cancer treated by mastectomy and adjuvant hormone therapy, followed by resection of a local recurrence, presented with fatigue and abdominal distension.
Comparison of VCV and PCV-VG modes on diaphragmatic function in diabetic patients undergoing laparoscopic colorectal surgery: a prospective randomized controlled study.
This prospective randomized controlled study compared pressure-controlled volume-guaranteed ventilation (PCV-VG) with volume-controlled ventilation (VCV) in 80 adults with type II diabetes undergoing elective…
Thyroid Function and Non-alcoholic Fatty Liver Disease in Children and Adolescent With Obesity: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined thyroid function in children and adolescents with obesity, comparing those with and without non-alcoholic fatty liver disease (NAFLD).
144 Weeks of bulevirtide monotherapy for chronic hepatitis D: Final and post-treatment results from a phase III randomized trial.
This phase III, multicentre randomized trial evaluated bulevirtide monotherapy in 150 patients with compensated chronic hepatitis D, comparing immediate 2 mg/day or 10 mg/day treatment for 144 weeks with delayed…
Pancreatic Duct Stenting During ERCP in Patients with Acute Biliary Pancreatitis: A Systematic Review and Meta-analysis.
This systematic review and random-effects meta-analysis assessed prophylactic pancreatic duct stenting during ERCP in adults with acute biliary pancreatitis.
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