Trending archive
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845 articles
May 202624
Basal Cell Carcinoma With Ductal Differentiation Presenting as a Large Unilocular Cyst on the Abdomen.
An 83-year-old Japanese man presented with a large unilocular cyst on the abdomen, initially suspected to be a sweat gland neoplasm based on a punch biopsy.
Blood biomarkers for the diagnosis of chorioamnionitis following preterm premature rupture of membranes: a systematic review and meta-analysis of studies since 2020.
This systematic review and meta-analysis assessed maternal blood biomarkers for predicting histological or clinical chorioamnionitis in women with preterm premature rupture of membranes (PPROM).
Thyroid Myofibroma in a Child With Turner Syndrome: Integrated Cytologic, Histopathologic, and Molecular Characterization.
A 9-year-old girl with Turner syndrome and a history of parotid myofibroblastic proliferation presented with a solitary thyroid nodule.
Uterine Myxoid Inflammatory Myofibroblastic Sarcoma (MIMS) Harboring Pathogenic KRAS Mutations and Expressing ER, PR, and CD10.
A 40-year-old woman presented with a uterine tumor characterized by a whorled architecture and myxoid stroma. Immunohistochemical analysis revealed positivity for CD10, estrogen receptor (ER), and progesterone receptor…
Intraoperative 5-Aminolevulinic Acid Fluorescence in Periocular Sebaceous Carcinoma: A Proof-of-Concept Case Report.
An 80-year-old man with biopsy-proven invasive sebaceous carcinoma involving the right upper eyelid and conjunctiva underwent planned orbital exenteration and sentinel lymph node biopsy.
Extra-appendiceal low-grade mucinous neoplasm-like lesions: clinicopathologic and molecular characteristics.
Three cases of low-grade appendiceal mucinous neoplasm (LAMN)-like lesions were identified in duplication cysts, distinct from the appendix.
What Are Computer-Assisted Methods Achieving in Fine-Needle Aspiration Cytology of the Pancreas? A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the accuracy of computer-assisted diagnosis (CAD) in fine-needle aspiration (FNA) cytology of the pancreas.
Visualization of Scattered Tumor Regression Following Neoadjuvant Chemoimmunotherapy With a Novel Intraoperative PET/CT Scanner.
Neoadjuvant chemoimmunotherapy is being explored in locally advanced head and neck squamous cell carcinoma (HNSCC), yet the spatial patterns of pathologic response and clinical implications remain poorly characterized.
Clinical-pathological correlation and outcomes of eyelid Merkel cell carcinoma: A series of four cases.
The report describes four patients with rapidly progressive eyelid tumours and variable local invasion. Histopathology showed neuroendocrine carcinoma with an immunohistochemical profile characteristic of Merkel cell…
Comparison of PD-L1 expression between biopsy specimens and surgical resection specimens in non-small cell lung cancer: a meta-analysis.
This meta-analysis compared PD-L1 positivity in biopsy and surgical resection specimens from patients with non-small cell lung cancer, drawing on 13 studies involving 966 patients.
Clinical presentation and histopathological correlation of ciliary body medulloepithelioma: A report of four cases.
Four patients with ciliary body medulloepithelioma presented with varied findings, including reduced visual acuity, ocular pain, and secondary glaucoma.
Primary Pulmonary Epithelioid Inflammatory Myofibroblastic Sarcoma With SQSTM1::ALK Fusion.
A 58-year-old woman presented with cough and shortness of breath, leading to the discovery of a right lung mass. Transbronchial needle aspiration revealed spindle cells in a lymphoplasmacytic background, raising…
Clinical Characteristics, Diagnostic Features, and Medical Treatment of Sinonasal Sarcoidosis: A Systematic Review.
This systematic review examined clinical presentation, diagnosis, and medical treatment of sinonasal sarcoidosis (SNS), drawing on 68 case reports, case series, and observational studies involving 369 patients.
NUT Midline Carcinoma of the Head and Neck: A Systematic Review and Pooled Survival Analysis.
NUT midline carcinoma (NMC) is an aggressive malignancy driven by NUTM1 fusions in poorly differentiated tumor cells. This pooled analysis evaluates the impact of primary tumor location on overall survival (OS) in head…
Current diagnostic methods for detecting avascular necrosis and irreversible bone death of the proximal pole of the scaphoid: a systematic review.
This systematic review examined how reliably MRI, CT, intraoperative findings and histology distinguish avascular necrosis (AVN) from irreversible bone death in the proximal scaphoid.
Odontogenic cyst with verrucous proliferation.
A 5-year-old girl presented with swelling of the right upper gingiva. Biopsy at another centre showed an apparent intraosseous cyst lined by stratified squamous epithelium with papillary growth.
Honeycomb-Like Mucinous Carcinoma of the Pancreas, Mimicking Serous Cystadenoma.
A patient with a resected pancreatic mass was found to have mucinous carcinoma, which presented as a honeycomb-like multinodular cystic mass.
Uterine intra-leiomyoma metastasis originating from primary breast cancer: A rare entity.
An asymptomatic African American woman underwent hysterectomy for pelvic organ prolapse six years after treatment for primary breast cancer.
Primary Anaplastic Lymphoma Kinase-Negative Breast Anaplastic Large Cell Lymphoma Without Breast Implant Association: A Case Report.
A 26-year-old woman with no history of breast implantation presented with right breast pain and a palpable mass persisting for 3 months. Imaging showed a complex cystic lesion suspicious for malignancy.
Fetal/Perinatal Lethal Gaucher Disease: A Case Series.
The report describes four fetuses with lethal perinatal Gaucher disease: one diagnosis was genetically confirmed and three were based on histology.
Disseminated MRSA and Myelokathexis Preceding AML with t(8;21) and ASXL1 Mutation.
A 13-year-old boy presented with two months of fever, pancytopenia, and disseminated MRSA abscesses. Bone marrow showed myelokathexis without blasts; evaluation did not support WHIM syndrome or another inborn error of…
Localized episcleral ALK-positive histiocytosis: a novel adult presentation confirmed by ALK gene rearrangement.
A 36-year-old woman presented with an episcleral nodule that resembled nodular scleritis. An excisional biopsy revealed foamy histiocytes and Touton-type giant cells, with strong ALK1 expression and confirmed ALK gene…
Merkel Cell Carcinoma With Divergent Differentiation-Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity.
A patient presented with a triphenotypic carcinoma on the left upper arm, characterized by a neuroendocrine carcinoma with Merkel cell features, a poorly differentiated carcinoma with squamous/ductal differentiation…
Eosinophilic Myenteric Ganglionitis in a Newborn: Case Report.
A male newborn presented with intestinal obstruction and was found to have intestinal malrotation. Histology showed colonic ganglion cells surrounded by a moderate eosinophilic infiltrate, consistent with eosinophilic…
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