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1003 articles
July 202624
Recognizing Ocular Milker's Nodule: Diagnostic Clues and Clinical Course in Two Dairy Workers.
Two dairy workers presented with vesiculoulcerative eyelid lesions and corneal epithelial defects due to ocular Milker's nodule, a zoonotic infection from Parapoxvirus.
Molecular epidemiology of Mycobacterium tuberculosis in the Middle East and North Africa: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the molecular epidemiology of Mycobacterium tuberculosis in the Middle East and North Africa, analyzing 13,194 isolates from 59 studies.
Evidence-based PET in musculoskeletal infectious and inflammatory diseases.
This systematic review assessed original clinical studies of [18F]FDG PET/CT for prosthetic joint infection, diabetic foot infection, spondylodiscitis, osteomyelitis, and rheumatoid arthritis.
A rapid turn for the worse: Steroid-responsive pulmonary haemorrhage in leptospirosis.
A 43-year-old man presented with fever and cough, initially treated for community-acquired pneumonia. He rapidly deteriorated, developing type 1 respiratory failure.
An unusual presentation of scrub typhus as tetany: A case report.
A patient with scrub typhus presented with symptomatic hypocalcaemia and hypophosphataemia, likely due to renal tubular electrolyte loss.
Abdominopelvic Actinomycosis Mimicking Malignant Tumors: Two Case Reports.
Two patients with abdominopelvic actinomycosis presented with non-specific symptoms such as abdominal pain and distension. Imaging studies revealed irregular masses suggestive of malignancy, but surgical pathology…
Mapping the prevalence of molecular markers of Plasmodium falciparum artemisinin partial resistance in Africa: a systematic review and spatiotemporal modelling study.
This systematic review and spatiotemporal modelling study integrated published and unpublished surveys with public molecular databases to map Plasmodium falciparum resistance markers across Africa.
Isolated Splenic Tuberculosis in an Immunocompetent Young Woman: A Diagnostic Challenge.
A 21-year-old immunocompetent woman presented with vague upper abdominal pain and weight loss, without constitutional symptoms. Examination showed splenomegaly without lymphadenopathy.
Ulceronecrotic Plaques, Patchy Scalp Alopecia and Visual Disturbance in a 46-Year-Old Man.
A 46-year-old incarcerated man with chronic hepatitis C and a history of intravenous drug use developed a rapidly progressive, pruritic eruption across the scalp, trunk, and limbs, with patchy scalp hair loss and…
Phase 2/3, Open-label, Randomized, Active-controlled Clinical Trial Evaluating the Safety and Efficacy of Imipenem/Cilastatin/Relebactam in Pediatric Patients From Birth to Less Than 18 Years With Gram-negative Bacterial Infections.
This multinational, open-label, randomized, active-controlled phase 2/3 estimation trial evaluated imipenem/cilastatin/relebactam (IMI/REL) in children from birth to under 18 years with hospital-acquired or…
Evaluation of nirmatrelvir/ritonavir treatment for COVID-19 on health-related outcomes: a global economic value systematic literature review.
This systematic literature review evaluated the economic and health-related outcomes of nirmatrelvir/ritonavir (NMV/r) treatment for mild to moderate COVID-19 in high-risk patients.
The relationship between asymptomatic bacteriuria and surgical site infection in hip fracture patients: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the relationship between peri-operative asymptomatic bacteriuria (ASB), its treatment, and surgical site infection (SSI) in hip fracture patients.
Legionnaire's disease with limbic encephalitis.
A 52-year-old man presented with limbic encephalitis and pneumonia caused by Legionella. The urinary antigen test confirmed Legionella infection, while cerebrospinal fluid cultures and sputum tests were negative for the…
Efficacy and safety of Janus kinase inhibitors in Behçet's disease: A systematic literature review.
Behçet's disease e (BD) is a chronic, relapsing, multisystem inflammatory disorder that if not successfully treated can lead to severe, organ or life-threatening complications.
Campylobacter beyond the gut: A case series of Campylobacter jejuni bacteraemia with atypical presentations.
A case of Campylobacter jejuni bacteraemia was presented, which is an uncommon manifestation of this pathogen typically associated with gastroenteritis.
Impact of influenza and pneumococcal vaccines on inflammatory response during suppressive antiretroviral therapy.
This secondary analysis of a prospective, randomized, double-blinded, placebo-controlled crossover trial examined inflammatory responses to influenza and pneumococcal vaccination in people with HIV receiving suppressive…
First Fatal Case of Adult Meningoencephalitis Caused by Pasteurella canis: An Autopsy Case Report.
A 25-year-old immunocompetent man developed otitis after his dog licked his ear. Following a febrile illness with headaches, he died 20 days later.
Efficacy and safety of doravirine/islatravir for HIV-1: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the efficacy and safety of the doravirine/islatravir (DOR/ISL) regimen for HIV-1 in 3,600 participants across seven randomized controlled trials.
Hemophagocytic lymphohistiocytosis secondary to disseminated histoplasmosis diagnosed by bone marrow smear microscopy and metagenomic next-generation sequencing: A case report and review of literature.
An immunocompetent patient presented with disseminated histoplasmosis, leading to rapid clinical deterioration and a diagnosis of hemophagocytic lymphohistiocytosis (HLH).
Effect of moderate or high versus low dose daily vitamin D on COVID-19 incidence: A double-blind, parallel-group randomized clinical trial.
This double-blind, parallel-group randomized trial evaluated the impact of moderate (4000 IU/day) or high (10,000 IU/day) versus low (400 IU/day) vitamin D doses on COVID-19 incidence among 955 participants.
Effectiveness and safety of eravacycline-based regimens for resistant Acinetobacter baumannii infections: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness and safety of eravacycline-based regimens in adults with resistant Acinetobacter baumannii infections.
Prevalence of neurocysticercosis among individuals with seizure presentations in South East Asia: A systematic review and meta- analysis.
This systematic review and meta-analysis estimated the prevalence of neurocysticercosis (NCC) among individuals with seizure presentations in South-East Asia.
Diagnostic stewardship for optimizing blood culture practices: a systematic review of clinical practice guidelines and evidence-based recommendations.
This systematic review evaluated clinical practice guidelines and evidence-based recommendations for optimizing blood culture (BC) practices to improve bloodstream infection (BSI) diagnosis.
Safety and immunogenicity of a reduced, homologous booster dose of the BNT162b2 mRNA COVID-19 vaccine: a single blind, randomized, non-inferiority follow-up trial.
This randomized controlled trial evaluated the safety and immunogenicity of a 10 μg versus 30 μg booster dose of the BNT162b2 mRNA COVID-19 vaccine in 132 healthy adults.
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