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845 articles
June 202624
Prenatal Diagnosis of Recurrent Alkuraya-Kučinskas Syndrome: A Rare Case Report.
A 24-year-old woman in a consanguineous marriage, with a previous pregnancy terminated after diagnosis of Alkuraya-Kučinskas syndrome (AKS), had first-trimester ultrasound findings of cystic hygroma and limb…
Lipomatous hamartoma of the semilunar valve exhibits molecular genetic characteristics of lipoma.
A 26-year-old woman presented with a symptomatic pulmonary valve lesion initially suspected to be a papillary fibroelastoma. Surgical intervention revealed a lipomatous hamartoma of the pulmonary valve.
Subcutaneous phaeohyphomycosis: ultrasound findings and histopathologic correlation.
A 60-year-old woman presented with a slowly growing subcutaneous nodule. Ultrasound revealed a well-circumscribed hypoechoic pseudocystic lesion with heterogeneous internal echoes and peripheral hypervascularity…
Extracranial Meningiomas of the Left Neck.
A 64-year-old woman presented with an extracranial meningioma in the left side of her neck. Histological examination and immunohistochemical staining confirmed the diagnosis.
Fibromyxoid Nephrogenic Adenoma Mimicking Renal Cell Carcinoma: A Diagnostic Pitfall in Fine-Needle Aspiration Cytology.
A 72-year-old man presented with a right renal mass, evaluated due to a history of nephrolithiasis. Fine-needle aspiration cytology revealed cloudy red fluid with scant epithelial cells, leading to a pre-operative…
Malignant adenomyoepithelioma of the breast: seven cases illustrating morphological diversity and diagnostic challenges.
This retrospective clinicopathological review describes seven women aged 45–74 years with malignant adenomyoepithelioma (M-AME) of the breast.
Cytological Diagnosis of Primary Cardiac Angiosarcoma Presenting With Multiple Serous Effusions: A Case Report With Cell Block.
A 42-year-old female presented with abdominal distension and exertional dyspnea, leading to the discovery of a cardiac space-occupying lesion and multiple serous effusions.
Myoepithelioma-like tumor of the vulvar region shows a quiet genome and heterogeneous detectable mechanisms of SMARCB1 inactivation: Integrated analysis of two cases and review of the literature.
Two cases of myoepithelioma-like tumor of the vulvar region (MELTVR) were analyzed, characterized by uniform epithelioid to spindle cells in myxoid stroma and complete loss of INI1 expression.
IgG4-related inflammatory pseudotumor presenting with refractory seizures: a diagnostic pitfall.
A patient with a 10-year history of immunoglobulin G4-related disease (IgG4-RD) presented with refractory focal seizures, which later progressed to a tumefactive brain lesion.
STR typing from punched FFPE tissues: resolving suspected contamination and fetal-maternal mixture in two cases.
Two casework applications used targeted punches from formalin-fixed, paraffin-embedded tissue followed by STR profiling. In one, a focus of high-grade urothelial carcinoma in a prostate surgical specimen prompted…
Occult Pulmonary Adenosquamous Carcinoma Presenting With Synchronous Colonic Metastases.
A 60-year-old woman with a substantial smoking history and COPD presented with a refractory exacerbation, without a discrete lung parenchymal mass.
Primary Cutaneous Rosai-Dorfman Disease Presenting as an Infiltrative Dorsal Nasal Mass With Deep Skeletal Muscle Involvement.
A 64-year-old woman had an 18-month history of a progressively enlarging, pruritic mass involving the nasal dorsum and both sidewalls.
Initial Clinical Experience With Partial Heart Transplantation for Mitral Valve Replacement: An Experimental Approach.
Two pediatric patients underwent orthotopic mitral partial heart transplantation using donor valves with preserved subvalvular apparatus.
Unusual morphologic features in molecularly defined high-grade sarcomas of the uterus.
This report details two cases of high-grade uterine sarcomas with unique genetic alterations. One case featured an FGFR1::TACC1 fusion and exhibited an atypical epithelioid morphology, while the other had an…
Cytological Features of Clear Cell Sarcoma in Exfoliative and Effusion Cytology Specimen-A Case Report and Literature Review.
A patient with metastatic clear cell sarcoma of soft tissue presented with malignant effusions in sputum, peritoneal fluid, and pericardial fluid.
Somatic BRCA1 and BRCA2 detection in homologous recombination deficiency testing: concordance of four sequencing workflows with the Myriad myChoice companion diagnostic.
This multicenter study assessed agreement between four tumor sequencing workflows and the Myriad myChoice companion diagnostic for BRCA1/BRCA2 variant detection in newly diagnosed ovarian cancer.
The prognostic value of tumour budding for survival in stage II and III colorectal cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether high-grade tumour budding (TB) predicts survival in stage II and III colorectal cancer.
Cytologic Detection of Metastatic Immature Teratomas in Two Young Patients With Unique Presentations.
Two young women presented with high-grade ovarian immature teratomas featuring metastatic immature neuroepithelial components.
An Atypical Skin Presentation of Adult-Onset Still's Disease With Histological Description: A Case Report.
A 30-year-old man presented with high spiking fever, odynophagia, diffuse arthralgia, and generalized asthenia, alongside a slightly pruritic erythematous maculopapular and urticarial rash that spread from his face and…
Ultrasonic Manifestations of Prostate Rhabdomyosarcoma: A Case Report and Literature Review.
An adult with prostatic rhabdomyosarcoma was evaluated after nonspecific early manifestations that can resemble benign prostatic disorders.
Primary salivary gland neuroendocrine carcinoma with multidisciplinary insights.
A 68-year-old man was diagnosed with primary large cell neuroendocrine carcinoma of the parotid. PET-CT showed two hypermetabolic nodules confined to the gland, with no distant metastasis.
Nail Langerhans Cell Histiocytosis: A Rare Case Series of Two Patients With Single-System and Multisystem Disease Presenting With Nail Lesions.
Two boys, aged 2 years and 19 months, developed nail abnormalities as the initial feature of Langerhans cell histiocytosis (LCH).
Diagnostic Dilemma and Therapeutic Challenges in EWSR1::PATZ1 Fusion Sarcomas: Insights From Two Patients.
The report describes two patients with EWSR1::PATZ1 fusion sarcoma, a rare soft-tissue and bone round-cell sarcoma. The tumors showed conventional round-cell morphology and could express both myogenic and neurogenic…
A randomized controlled trial on the impact of bovhyaluronidase azoximer on ejaculate biofilms in patients with chronic prostatitis.
This randomized controlled trial evaluated antibiotics plus bovhyaluronidase azoximer versus antibiotics alone in patients with chronic bacterial prostatitis and infertility.
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