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845 articles

September 20262

August 202622

Case ReportDermatology

From Pustules to Pruritus: A Novel IL36RN Frameshift Variant Reveals a Triple Biologic Paradox and a Th17-To-Th2 Phenotypic Transition.

A 64-year-old woman with longstanding psoriasis vulgaris, asthma, allergic rhinitis, and a family history of atopy developed generalized pustular psoriasis after biologic treatment.

J DermatolAug 31, 2026Read case
Clinical ResearchOncology (Medical)

Prognostic models and predictors of recurrence in resectable colorectal liver metastases: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed prognostic models and recurrence predictors after curative-intent locoregional treatment of colorectal liver metastases.

Crit Rev Oncol HematolAug 30, 2026Read summary
Case ReportOrthopedic SurgeryOpen access

De novo osteosarcoma following prolonged denosumab treatment for giant cell tumor of bone at an anatomically distant site: a case report.

A patient treated with prolonged denosumab for giant cell tumor of bone (GCTB) developed osteosarcoma at an anatomically distant site from the original tumor.

Skeletal RadiolAug 29, 2026Read case
Case ReportGeneral Surgery

Post-pancreatectomy Liver Injury After Mayo Clinic Class Ia Celiac Axis Resection: Illustration of This Newly Described Entity with Delayed Hepatic Artery Revascularization.

A 59-year-old patient with locally advanced pancreatic body cancer received extended neoadjuvant FOLFIRINOX and underwent pancreatosplenectomy with Mayo Clinic class Ia celiac artery resection.

Ann Surg OncolAug 29, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Cytological Identification of a Rhabdoid Variant of Pancreatic Neuroendocrine Neoplasm.

A 48-year-old woman presented with an incidental pancreatic head mass. Cytological analysis from endoscopic ultrasound-guided fine-needle aspiration revealed tumor cells with eccentric nuclei and prominent eosinophilic…

CytopathologyAug 27, 2026Read case
Clinical ResearchOncology (Medical)

What is the prognostic significance of positive lymph nodes at the circumferential resection margin in rectal cancer: a systematic review.

This systematic review examined whether rectal cancer involving the circumferential resection margin (CRM) through metastatic lymph nodes carries the same prognosis as CRM involvement from direct tumor extension.

J Gastrointest SurgAug 27, 2026Read summary
Case ReportDermatology

Generalised eruptive histiocytosis mimicking lymphoma relapse in a patient with previous diffuse large B-cell lymphoma.

A 92-year-old man previously treated for diffuse large B-cell lymphoma, including radiotherapy for a cutaneous relapse, developed asymptomatic erythematous-to-violaceous papules and nodules on his face, trunk, and upper…

LancetAug 27, 2026Read case
Case ReportGeneral SurgeryOpen access

The Brief Case: Acute Gangrenous Appendicitis with Incidental Schistosoma Eggs in a Malian Migrant.

A 28-year-old migrant from Mali presented with 24 hours of right lower abdominal pain, anorexia, and low-grade fever. Examination, inflammatory markers, and ultrasound supported acute appendicitis.

Am J Trop Med HygAug 25, 2026Read case
Case ReportNephrology

Spurious undetectable albumin due to hemodialysis catheter lock contamination.

A clinically stable 46-year-old man receiving maintenance hemodialysis had a routine albumin result below the assay’s analytical measuring range (<2 g/L), despite no clinical signs of severe hypoalbuminemia.

Clin Chim ActaAug 25, 2026Read case
Clinical ResearchGeneral Surgery

Near-infrared Autofluorescence Probe Versus Visual Identification for Parathyroid Detection and Functional Preservation During Total Thyroidectomy: A Randomized Controlled Trial.

This single-center, prospective randomized trial compared PTeye-guided near-infrared autofluorescence with visual identification of parathyroid glands during first-time total thyroidectomy.

Ann SurgAug 25, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Crizotinib versus observation or placebo for surgically resected early-stage ALK-positive non-small-cell lung cancer (Eastern Cooperative Oncology Group-American College of Radiology Imaging Network E4512): a phase 3 trial.

This multicentre, randomised phase 3 trial compared up to 2 years of adjuvant crizotinib with observation in patients with resected, early-stage ALK-positive non-small-cell lung cancer (NSCLC).

Lancet Respir MedAug 25, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

Cytologic Features of Inflammatory Rhabdomyoblastic Tumor Using Conventional and Liquid-Based Cytology Preparations: A Case Report.

A man in his 60s with pharyngeal discomfort was diagnosed with tonsillar diffuse large B-cell lymphoma. Staging PET-CT also showed focal uptake in the left tibialis anterior muscle, initially raising concern for…

Diagn CytopatholAug 25, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Morphology and Beyond - A Rare Case of Metastatic Succinate Dehydrogenase-Deficient Paraganglioma of the Vulva.

A 35-year-old woman with a history of pheochromocytoma presented with a vulvar mass. Histology showed nests and trabeculae of neuroendocrine-appearing cells in a Zellballen pattern, resembling other nested tumors.

Ann Afr MedAug 25, 2026Read case
Case ReportUrology

PSMA-Avid Metastatic Prostate Cancer With Intense Penile Uptake on PET/CT: A Rare Site of Spread.

A 64-year-old man with biopsy-proven advanced prostatic adenocarcinoma (cT3bN1M1, Gleason 4+4=8) had intense, diffuse, homogeneous PSMA uptake throughout the corpora cavernosa along the penile shaft on PET/CT…

Clin Nucl MedAug 24, 2026Read case
Case ReportPathology (Anatomic & Clinical)

Sclerosing epithelioid fibrosarcoma with initial presentation as pulmonary masses: clinicopathological characteristics and diagnostic challenges.

This report analysed four cases of sclerosing epithelioid fibrosarcoma (SEF) presenting initially as solitary or multiple pulmonary masses.

PathologyAug 24, 2026Read case
Case ReportEndocrinology

Distinguishing autoimmune recurrence from rejection in simultaneous pancreas-kidney transplantation recipients: A case-based short review.

Simultaneous pancreas-kidney (SPK) transplantation provides durable glycemic control and survival benefit for selected patients with Type 1 diabetes and end-stage renal disease.

Am J Med SciAug 22, 2026Read case
Clinical ResearchPathology (Anatomic & Clinical)

Diagnostic performance of panfungal PCR on tissue specimens for the diagnosis of invasive fungal diseases: a systematic review and meta-analysis of the Fungal PCR Initiative (FPCRI).

This systematic review and meta-analysis evaluated the diagnostic performance of panfungal PCR on tissue specimens for invasive fungal diseases.

J Clin MicrobiolAug 21, 2026Read summary
Case ReportDermatology

Multifocal Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type, Presenting on Face and Chest: Complete Remission With R-CHOP.

A 79-year-old woman developed rapidly enlarging erythematous-to-violaceous tumors and plaques on her face, chest, left upper arm, and upper back.

Am J DermatopatholAug 21, 2026Read case
Clinical ResearchNephrology

Urinary Extracellular Vesicles as a Source of Biomarkers for Kidney Allograft Rejection: A Systematic Review.

This systematic review assessed urinary extracellular vesicle (uEV) biomarkers for detecting kidney allograft rejection. Sixteen studies were included, using varied vesicle-isolation methods and proteomic…

TransplantationAug 21, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

Fluorescence patterns and longitudinal changes of oral potentially malignant disorders (OPMDs) lesions using biofluorescence imaging: case reports.

Two patients with oral potentially malignant disorders (OPMDs) were monitored using biofluorescence imaging alongside white-light imaging.

Photodiagnosis Photodyn TherAug 20, 2026Read case
Clinical ResearchGeneral SurgeryOpen access

Positive Intraoperative Frozen Section during Surgery for Junctional and Gastric Cancer: Should We Re-Resect? A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis assessed whether re-excision after a positive intraoperative frozen section is associated with improved overall survival in patients undergoing curative-intent…

Ann Surg OncolAug 20, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Pathologic Complete Response (pCR) Rate and Predictors of Response to Taxane, Trastuzumab, and Pertuzumab in HER2‑Positive Breast Cancer: Secondary Analyses of EA1181/CompassHER2 pCR.

This single-arm phase II trial evaluated neoadjuvant taxane, trastuzumab, and pertuzumab (THP) followed by surgery in patients with clinical stage II/IIIa HER2-positive breast cancer.

J Clin OncolAug 20, 2026Read summary

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