Trending archive

Every article that has appeared in Trending stays here. Search by title, journal, author or PMID, and narrow by date.

470 articles

November 20265

Clinical ResearchEmergency Medicine

Performance of the i-Gel Versus King LT-D by Combat Medics Under Simulated Tactical Conditions: A Prospective Randomized Crossover Study.

This prospective randomized crossover study compared i-gel and King LT-D placement by active-duty combat medics after exertion while wearing full combat gear, using a high-fidelity manikin.

Mil MedNov 1, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Pain-Related Outcome Domains and Measures in Randomized Controlled Trials of Treatment for Acute Abdominal Pain: A Systematic Review.

This PRISMA-guided systematic review mapped pain-related outcome domains and measures in randomized controlled trials of acute abdominal pain treatment.

Eur J PainNov 1, 2026Read summary
Clinical ResearchOrthopedic Surgery

The Effect of Virtual Reality on Anxiety and Vital Signs in Patients Undergoing Total Knee Replacement Surgery: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether intraoperative virtual reality affected anxiety and vital signs in 70 patients undergoing total knee replacement.

Comput Inform NursNov 1, 2026Read summary
Clinical ResearchNeurology

The Impact of Outcome Measures for Responder Analyses in Placebo-Controlled Trials of Pharmacological Treatments for Neuropathic Pain.

This meta-analysis examined how dichotomous responder definitions affect estimated treatment effects in placebo-controlled pharmacological trials for neuropathic pain.

Eur J PainNov 1, 2026Read summary
Case ReportAnesthesiologyOpen access

Pump-Predicted Ciprofol Ce50 for Suppressing the Cardiovascular Response to Tracheal Intubation During Fixed Sufentanil-Esketamine Induction: An Age-Stratified Dixon Up-and-Down Study.

To estimate the ciprofol pump-predicted effect-site target concentration associated with a 50% probability of suppressing the cardiovascular response to tracheal intubation (Ce50) during fixed sufentanil-esketamine…

Drug Des Devel TherNov 1, 2026Read case

October 202619

Clinical ResearchPulmonologyOpen access

Airway Pressure Release Ventilation Versus Conventional Ventilation in Adults With or at Risk for Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis of Randomized Trials.

This systematic review and meta-analysis of randomized trials compared airway pressure release ventilation (APRV) with conventional invasive ventilation in adults with ARDS, acute lung injury, or conditions placing them…

LungOct 31, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Impacts of Oliceridine versus Sufentanil on the Quality of Postoperative Recovery in Elective Gynecological Laparoscopic Surgery: A Randomized Controlled Trial.

This single-centre randomized controlled trial compared patient-controlled intravenous analgesia with oliceridine or sufentanil in 136 women aged 18–65 years undergoing elective laparoscopic gynecological surgery.

Drug Des Devel TherOct 31, 2026Read summary
Clinical ResearchCardiology

Incidence of Intensive Care Unit Delirium After Heart Surgery: A Feasibility Study of a Forest Environment Intervention.

This randomized feasibility study evaluated forest-environment and light-exposure interventions, compared with standard care, in adults undergoing elective cardiac surgery at a tertiary ICU in Austria.

Nurs Crit CareOct 30, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Visual rigid laryngoscope versus Macintosh laryngoscope using low-dose relaxants in thyroid surgery.

This single-centre randomized controlled trial compared visual rigid laryngoscopy (VRL) with Macintosh laryngoscopy for tracheal intubation in patients undergoing elective thyroid surgery with intraoperative…

PeerJOct 30, 2026Read summary
Clinical ResearchCardiology

Efficacy of Stellate Ganglion Block for Preventing Postoperative Atrial Fibrillation After Cardiac Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.

This single-center, randomized, double-blind, placebo-controlled trial assessed whether preoperative ultrasound-guided right stellate ganglion block (SGB) prevents postoperative atrial fibrillation (POAF) in patients…

J Am Heart AssocOct 30, 2026Read summary
Case ReportOrthopedic SurgeryOpen access

Effect of Intravenous Acetaminophen on Preemptive Multimodal Analgesia for Pediatric Osteotomy Correction Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.

Children undergoing Osteotomy correction surgery can experience substantial postoperative pain and frequently require opioids.

Drug Des Devel TherOct 30, 2026Read case
Clinical ResearchEmergency Medicine

Prehospital Analgesia in Trauma: A Systematic Review of Current Evidence.

This systematic review assessed the safety and effectiveness of pharmacologic analgesia given before hospital arrival to acutely injured adults aged over 15 years.

Emerg Med AustralasOct 29, 2026Read summary
Clinical ResearchObstetrics & Gynecology

The Effect of Using Heated IV Fluids With Underbody Warmers on Maternal and Neonatal Well-Being in Cesarean Delivery Operations: A Randomized Clinical Trial.

This randomized clinical trial at a university hospital compared underbody warming alone, underbody warming plus heated IV fluids, and passive blanket heating in 105 pregnant patients undergoing cesarean delivery.

AORN JOct 29, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Analgesic efficacy of regional and local analgesic techniques for anterior cruciate ligament reconstruction in adults undergoing general anesthesia: a systematic review and network meta-analysis.

This systematic review and Bayesian network meta-analysis compared regional and local analgesic techniques in adults undergoing anterior cruciate ligament reconstruction under general anesthesia.

BMC AnesthesiolOct 29, 2026Read summary
Clinical ResearchGeneral Surgery

Postoperative Pain Treatment After Pancreatic Surgery: A Systematic Review With Meta-Analyses and Trial Sequential Analyses.

This PROSPERO-registered systematic review and meta-analysis examined postoperative analgesia after total pancreatectomy, pancreaticoduodenectomy, and distal pancreatectomy.

Eur J PainOct 28, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effect of intraoral glossopharyngeal nerve block on hemodynamic response to mouth retractor placement in transoral robotic surgery: a randomized clinical trial.

This prospective, single-centre randomized clinical trial assessed whether bilateral intraoral glossopharyngeal nerve block attenuates the blood-pressure response to mouth retractor placement during transoral robotic…

J Robot SurgOct 28, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Comparison of sterile silicone studs and scalp infiltration with lignocaine for the attenuation of the hemodynamic and stress response to skull pin insertion during craniotomy in pediatric neurosurgical patients: a randomized controlled trial : Sterile silicone studs versus lignocaine infiltration for skull pin insertion.

This randomized controlled trial compared sterile silicone studs (SSS) with lignocaine infiltration for skull pin insertion in 64 children aged 12 years or younger undergoing neurosurgery.

Childs Nerv SystOct 28, 2026Read summary
Clinical ResearchAnesthesiology

Haemodynamic and Respiratory Effects of Dexmedetomidine as an Adjuvant to Oxycodone Patient-Controlled Analgesia After Lumbar Spinal Fusion: A Post Hoc Analysis of the DoseRespDex Randomised Controlled Trial.

This post hoc analysis of a randomised, double-blind, placebo-controlled trial examined haemodynamic and respiratory effects of dexmedetomidine added to oxycodone patient-controlled analgesia in 98 adults undergoing…

Acta Anaesthesiol ScandOct 27, 2026Read summary
Clinical ResearchPulmonology

Comparison of the Safety and Efficacy of Remimazolam for Sedation in Adults Undergoing Fiberoptic Bronchoscopy: A Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis of randomized controlled trials compared remimazolam with other sedatives in adults undergoing fiberoptic bronchoscopy.

J Bronchology Interv PulmonolOct 27, 2026Read summary
Clinical ResearchAnesthesiology

Erector spinae plane block added to intercostal nerve block versus intercostal nerve block alone for postoperative analgesia in video-assisted thoracoscopic surgery: A randomized controlled trial.

This prospective, randomized controlled trial compared surgical intercostal nerve block (INB) alone with INB plus single-injection erector spinae plane block (ESPB) in 60 adults undergoing elective three-port…

PLoS OneOct 27, 2026Read summary
Case ReportCardiothoracic SurgeryOpen access

Effect of Preoperative Intranasal Dexmedetomidine on Postoperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting.

To evaluate the effects of preoperative intranasal dexmedetomidine on postoperative myocardial injury biomarkers in patients undergoing on-pump coronary artery bypass grafting (CABG).

Drug Des Devel TherOct 27, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Effect of Adding Esketamine to Patient-Controlled Intravenous Analgesia on Rebound Pain After Interscalene Brachial Plexus Block: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether adding esketamine to postoperative patient-controlled intravenous analgesia (PCIA) reduces rebound pain after interscalene brachial plexus block in patients undergoing…

Drug Des Devel TherOct 27, 2026Read summary
Case ReportAnesthesiologyOpen access

Sequential Lidocaine and Liposomal Bupivacaine for Popliteal Sciatic Nerve Block in Foot and Ankle Surgery: A Randomized Controlled Trial.

In foot and ankle surgery, prolonged analgesia after popliteal sciatic nerve block (PSNB) may be accompanied by delayed motor recovery.

Drug Des Devel TherOct 26, 2026Read case
Case ReportAnesthesiologyOpen access

Quadratus Lumborum versus Transversus Abdominis Plane Block with Oxycodone or Sufentanil for Recovery Quality After Laparoscopic Gastrointestinal Cancer Surgery: A Factorial Randomized Trial.

Quadratus lumborum block (QLB) theoretically provides broader visceral analgesia than transversus abdominis plane block (TAPB), while oxycodone, a dual μ- and κ-opioid receptor agonist, may offer superior visceral pain…

Drug Des Devel TherOct 24, 2026Read case

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text

Prefer listening? Personalized audio digests are available with Pro.