Trending archive
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137 articles
October 20264
Adult-Onset Henoch-Schönlein Purpura Triggered by Isotretinoin with Persistent Polyarthritis and Isolated Cutaneous-Gastrointestinal Involvement: A Case Report.
A 30-year-old woman developed palpable purpura, abdominal pain, and symmetric polyarthritis three weeks after starting isotretinoin.
Anaphylaxis Following Intravenous Methylprednisolone Sodium Succinate: A Case Report.
A 45-year-old woman with rheumatoid arthritis developed generalized pruritic erythema and raised lesions, dyspnea, hypoxemia, bradycardia, and reduced consciousness within 5 minutes of starting intravenous…
Suspected allergic bronchopulmonary candidiasis in a patient with concurrent multidrug-resistant bacterial pneumonia: A case report.
A 70-year-old man with a history of hypertension and cerebral infarction presented with sudden right limb weakness and was diagnosed with hemorrhagic cerebral infarction.
Treatment of Multifood Allergy With Omalizumab or Multiallergen Oral Immunotherapy: A Randomized Clinical Trial.
This randomized clinical trial compared the efficacy of omalizumab versus multiallergen oral immunotherapy (MOIT) in treating multifood allergies in participants aged 1 to 55 years.
September 202620
Short-term nasal decongestant as bridge therapy with intranasal corticosteroids in children with persistent allergic rhinitis: A randomized controlled trial.
This prospective, open-label, single-centre randomised trial compared intranasal corticosteroid (INS) alone with INS plus five days of oxymetazoline in children aged 4–17 years with moderate-to-severe persistent…
Asthma Intervention with Residential Ventilation and Air Cleaner (AIRVAC) Study: A 4-arm parallel-group randomized controlled trial protocol.
The AIRVAC study is a 4-arm parallel-group randomized controlled trial evaluating the long-term effectiveness of energy recovery ventilators and portable air cleaners in improving asthma outcomes among children and…
Levels of IgG subclasses 1-4 in BT595, a 10% IVIG: A sub-analysis of a clinical trial.
This multicenter, open-label clinical trial evaluated the pharmacokinetics of IgG subclasses in patients with primary immunodeficiency receiving 10% IVIG BT595.
Mild Phenotype in Functionally Validated STAT1 Gain-of-Function Disease Due to a Novel DNA-Binding Variant.
A case report describes four patients with STAT1 gain-of-function disease, focusing on three related individuals with a novel p.Leu400Pro variant.
Anaphylaxis to both pegfilgrastim and sargramostim in a patient with diffuse large B-cell lymphoma.
A woman in her early 60s with stage 3A diffuse large B-cell lymphoma experienced anaphylaxis to pegfilgrastim after her first cycle of R-CHOP chemotherapy, presenting with syncope and severe hypotension.
Acute Hepatocellular Drug-induced Liver Injury following Cosmetic Liquid Lipo Injection Complicated by Anaphylactic Reaction to N-acetylcysteine.
A 31-year-old woman without prior liver disease developed nausea, vomiting, jaundice, and generalized pruritus shortly after a cosmetic “liquid lipo” injection containing deoxycholic acid, phosphatidylcholine, and…
Complicated allergic fungal rhinosinusitis: diagnostic complexities and management strategies.
A man in his 60s presented with diplopia, headache, and facial numbness, leading to a diagnosis of bilateral abducens nerve palsy and partial right third nerve palsy.
Symptomatic Interventions for Allergic Rhinitis Without Comorbid Asthma: A Dose-Stratified Network Meta-analysis.
This systematic review and dose-stratified network meta-analysis compared symptomatic treatments for seasonal and perennial allergic rhinitis in patients without comorbid asthma.
Novel TRAC variant causing autosomal recessive TCR-alpha/beta deficient immunodeficiency 7.
Monozygotic twin brothers presented in early infancy with severe, recurrent diarrhoea and profound T-cell lymphopenia. Immunological assessment revealed significantly reduced immunoglobulins and very low CD3+, CD4+, and…
Prenatal maternal stress and the risk of allergic rhinitis in offspring: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether maternal stress during pregnancy is associated with allergic rhinitis (AR) in offspring. It pooled findings from 9 studies involving 40,630 participants.
Trial of a Maternal Diet Rich in Eggs and Peanuts to Reduce Infant Allergy.
This multicenter randomized controlled trial investigated the effect of a maternal diet rich in eggs and peanuts on the development of food allergies in infants.
IL-2 mutein selectively expands thymic memory Tregs with increased transendocytosis in healthy participants.
This randomized, single-ascending-dose trial in healthy human participants examined how the IL-2 mutein MK-6194 affects regulatory T-cell (Treg) subsets and function.
Déjà vu.
A male in his mid-20s presented with fever, purpuric rash, neuropathy, marked eosinophilia, hepatic dysfunction, and extensive multisystem thrombosis.
A Novel De Novo STAG1 Variant at the RAD21 Binding Interface Is Associated With Hypoglycemia, Recurrent Fever, Immunodeficiency and Features of Classical Cohesinopathies.
A 5-year-old boy had developmental delay and intellectual disability with feeding difficulties, alongside hypoglycemia, recurrent fever, and immunodeficiency.
Efficacy and Predictors of Response to Biologic Therapy and Endoscopic Sinus Surgery in Patients With Nasal Polyps: A Systematic Review.
This systematic review compared efficacy and response predictors for biologics and endoscopic sinus surgery (ESS) in adults with chronic rhinosinusitis with nasal polyps, synthesizing randomized trials and subgroup…
Prevalence and risk factors of recurrent respiratory tract infections in preschool children: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed recurrent respiratory tract infection (RRTI) prevalence and associated risk factors in preschool children. Ten studies including 15,271 children were analyzed.
Dupilumab efficacy and safety in patients with allergic bronchopulmonary aspergillosis.
This double-blind phase 2 randomised trial evaluated dupilumab versus placebo in patients aged 12 years or older with asthma and allergic bronchopulmonary aspergillosis (ABPA).
Effect of repeated exposure to an identical multi-user virtual reality anaphylaxis scenario on paramedic trainee performance: a randomized controlled trial.
This randomized controlled trial evaluated the impact of repeated exposure to a virtual reality (VR) anaphylaxis scenario on the performance of 125 paramedic trainees.
Epidemic Thunderstorm Asthma in China: A Systematic Review of an Artemisia-Associated Phenotype.
This systematic review examines epidemic thunderstorm asthma (ETSA) in China, focusing on its association with Artemisia pollen.
Levocetirizine-induced paradoxical fixed drug eruption: A case report with causality assessment.
A patient developed a fixed drug eruption (FDE) after self-medicating with levocetirizine, presenting with hyperpigmented patches that progressed to blisters.
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