Epidemic Thunderstorm Asthma in China: A Systematic Review of an Artemisia-Associated Phenotype.
Clin Rev Allergy ImmunolSep 2, 2026 (epub)
Le Cui, Xiaohong Lyu, Lauren Mazin et al.
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In 30 seconds
This systematic review examines epidemic thunderstorm asthma (ETSA) in China, focusing on its association with Artemisia pollen. It synthesizes data from 54 studies, revealing that 40% to 60% of affected individuals lacked a prior asthma diagnosis. The review highlights significant differences in allergen profiles between China and regions traditionally associated with grass pollen.
Key findings
- Approximately 40% to 60% of ETSA cases in China occurred in individuals without a prior asthma diagnosis.
- Chinese reports frequently identified mugwort (Artemisia) sensitisation over ryegrass sensitisation.
- Recurrent ETSA events were documented in various localities across northern and north-western China.
Why it matters
Understanding the unique allergen profiles and clinical features of ETSA in different regions can aid clinicians in recognizing and managing this condition, particularly in populations with varying sensitivities.