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1357 articles

October 202624

Clinical ResearchOtolaryngology (ENT)Open access

Efficiency of different approaches in teaching tracheal suctioning procedure to caregivers of tracheostomy patients: randomized controlled study.

This randomized controlled study compared simulation-based and mobile application training with routine bedside instruction for primary caregivers of people with tracheostomies, including patients with head and neck…

Support Care CancerOct 31, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Urinary and sexual functional outcomes in female patients following elective lumbar spine surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis examined postoperative urinary and sexual functional outcomes in female patients undergoing elective lumbar fusion or disc replacement.

Neurosurg RevOct 31, 2026Read summary
Clinical ResearchPulmonologyOpen access

Breathing Exercises as Adjunct Therapy in Adult Asthma: A Systematic Review.

This systematic review assessed breathing retraining as an adjunct to pharmacological treatment in adults with asthma. It included 15 studies involving 1,786 participants: 12 randomised trials, one quasi-randomised…

F1000ResOct 31, 2026Read summary
Clinical ResearchPulmonologyOpen access

Airway Pressure Release Ventilation Versus Conventional Ventilation in Adults With or at Risk for Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis of Randomized Trials.

This systematic review and meta-analysis of randomized trials compared airway pressure release ventilation (APRV) with conventional invasive ventilation in adults with ARDS, acute lung injury, or conditions placing them…

LungOct 31, 2026Read summary
Clinical ResearchInternal Medicine (General)

The experience of family caregivers when their loved one is home hospitalized: a mixed methods analysis of a randomized controlled trial.

This mixed-methods analysis examined family caregivers of patients in a multicentre randomised controlled trial of rural home hospital care in the USA and Canada.

Age AgeingOct 31, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Impacts of Oliceridine versus Sufentanil on the Quality of Postoperative Recovery in Elective Gynecological Laparoscopic Surgery: A Randomized Controlled Trial.

This single-centre randomized controlled trial compared patient-controlled intravenous analgesia with oliceridine or sufentanil in 136 women aged 18–65 years undergoing elective laparoscopic gynecological surgery.

Drug Des Devel TherOct 31, 2026Read summary
Clinical ResearchNeurologyOpen access

Pharmacological Interventions for Neurological Manifestations of Ataxia-Telangiectasia: An Updated Systematic Review and Meta-analysis of Randomized Controlled Trials.

This updated systematic review and meta-analysis examined randomized trials of pharmacological treatments for neurological manifestations of ataxia-telangiectasia in children and adults.

CerebellumOct 31, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Early functional deterioration during first-line ICI-based therapy in advanced NSCLC: implications for supportive care.

This secondary exploratory analysis of prospectively collected data from a randomized pulmonary rehabilitation trial assessed early functional change in 42 people receiving first-line immune checkpoint inhibitor–based…

Support Care CancerOct 31, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Glucose and insulin responses to monk fruit-based sweetener formulations and their effects on appetite, liking and wanting, and energy intake (GREEN): a randomized double-blind, crossover study.

This randomized, double-blind, crossover study compared three monk fruit-based sweetener formulations (MF1–MF3) with sucrose and sucralose in 30 healthy adults.

Eur J NutrOct 31, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Postural control differences in children who are deaf or hard of hearing: A systematic review and meta-analysis of postural sway outcomes.

This systematic review and meta-analysis examined static posturography findings in children who are deaf or hard of hearing (DHH), compared with typically hearing peers.

Gait PostureOct 31, 2026Read summary
Clinical ResearchCardiology

Circulating biomarkers linking heart failure and chronic obstructive pulmonary disease: Toward an integrated biological framework - A systematic review.

This systematic review examined circulating biomarkers studied in both heart failure (HF) and chronic obstructive pulmonary disease (COPD), assessing their diagnostic, prognostic, and pathophysiological relevance.

Biomed PharmacotherOct 31, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Digital Health Services and Healthcare Management Outcomes: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed digital health services—including telemedicine, telemonitoring, virtual consultations, and remote care—against conventional care across 21 eligible studies.

J Vis ExpOct 30, 2026Read summary
Clinical ResearchPediatricsOpen access

Space changes after premature loss of mandibular second primary molars: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed space changes after premature extraction of mandibular second primary molars in children aged 4–9 years.

BMC Oral HealthOct 30, 2026Read summary
Clinical ResearchGeriatricsOpen access

Prevalence of fall risk and fear of falling among older adults in the Middle East and North Africa: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis estimated fall risk and fear of falling among adults aged 60 years or older in the Middle East and North Africa (MENA).

J Glob HealthOct 30, 2026Read summary
Clinical ResearchNeurologyOpen access

The effect of acupuncture-rehabilitation therapy on brain functional plasticity in motor aphasia after ischemic stroke: a randomized clinical neuroimaging trial.

This randomized clinical neuroimaging trial assigned 26 patients with motor aphasia after ischemic stroke to conventional rehabilitation (CR) or CR plus acupuncture-rehabilitation (A-R); 26 healthy controls provided…

Brain Imaging BehavOct 30, 2026Read summary
Clinical ResearchGeriatrics

The Effects of Virtual Reality Group Reminiscence Therapy on Agitation, Cognition, Depression and Social Function in Patients With Alzheimer's Disease.

This assessor-blinded randomised controlled trial evaluated multisensory virtual reality group reminiscence therapy in 60 people with Alzheimer’s disease, comparing twice-weekly 40-minute sessions for 8 weeks with…

PsychogeriatricsOct 30, 2026Read summary
Clinical ResearchPediatrics

Effects of Parent-Involved Digital Health Interventions on Adiposity-Related Outcomes and Behaviors in Children and Adolescents With Overweight or Obesity: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined randomized controlled trials of parent-involved digital health interventions for children and adolescents with overweight or obesity.

J Med Internet ResOct 30, 2026Read summary
Clinical ResearchPediatricsOpen access

Nurse-Led treatment strategy based on asthma score and oxygen requirement in children with acute reversible bronchoconstriction: A randomised controlled non-inferiority trial.

This multicentre, open-label, randomised non-inferiority trial compared nurse-led treatment guided by the oxygen-adjusted Childhood Asthma Score (CAS O2) with the standard CAS protocol in children aged 2–18 years…

PLoS OneOct 30, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Effects of a music-accompanied multimodal exercise program on trunk endurance, stress, and anxiety in university students: a randomized controlled trial.

This randomized controlled trial evaluated a 12-week, music-accompanied program combining core stabilization, diaphragmatic breathing, and relaxation in 80 university students assigned to intervention or waitlist…

Rev Assoc Med Bras (1992)Oct 30, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Community health worker intervention to prevent incident type 2 diabetes: A cluster randomized trial.

This pragmatic cluster-randomized controlled trial tested whether a 12-month community health worker (CHW) program could prevent type 2 diabetes in adults aged 18–75 years with prediabetes receiving care at two New York…

PLoS OneOct 30, 2026Read summary
Clinical ResearchPsychiatryOpen access

Unmasking Panic Disorder in Adults with Leukemia: A Systematic Review of Prevalence, Risk Factors, and Management.

This PRISMA-guided systematic review examined panic disorder and anxiety in adults with leukemia, searching four databases for studies published from 2015 to July 20, 2025.

Psychopharmacol BullOct 30, 2026Read summary
Clinical ResearchNeurology

The Effect of Bupropion in Peripheral Neuropathic Pain A Randomized, Double-Blind, Placebo-Controlled Study.

This randomized, double-blind, placebo-controlled crossover study assessed bupropion for peripheral neuropathic pain and whether response varied with conditioned pain modulation (CPM) or sensory phenotype.

Eur J PainOct 30, 2026Read summary
Clinical ResearchGastroenterologyOpen access

HEPATIC ENCEPHALOPATHY IN ALCOHOL-RELATED CIRRHOSIS:A SYSTEMATIC REVIEW OF CLINICAL CHARACTERISTICS, THERAPEUTIC STRATEGIES, AND PROGNOSTIC OUTCOMES.

This systematic review examined hepatic encephalopathy (HE) characteristics, treatment strategies and outcomes in adults with alcohol-related cirrhosis or documented alcohol consumption.

Arq GastroenterolOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

Predictors of chronic arthralgia after chikungunya virus infection: a systematic review and meta-analysis.

This systematic review and meta-analysis examined predictors of chronic arthralgia, defined as lasting at least 3 months, after laboratory-confirmed chikungunya infection.

J Travel MedOct 30, 2026Read summary

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