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1382 articles
September 202624
Biopsychosocial Antecedents and Symptom Burden Among Children Undergoing Cancer Treatment: A Systematic Review.
This systematic review synthesized evidence on factors associated with symptom burden in children under 18 undergoing cancer treatment. Following screening of 5,254 articles, 74 were included.
A Phase 3 Trial of Vosoritide in Children with Hypochondroplasia.
This phase 3, multicenter, randomized, placebo-controlled trial evaluated once-daily vosoritide in children aged 3 to less than 18 years with hypochondroplasia.
Neurogenic Paradoxical Vocal Fold Motion: A Systematic Review of Central and Pheripheral Nervous System Disorders.
This PRISMA-guided systematic review examined paradoxical vocal fold motion (PVFM) associated with confirmed central or peripheral neurological disorders.
A Novel De Novo STAG1 Variant at the RAD21 Binding Interface Is Associated With Hypoglycemia, Recurrent Fever, Immunodeficiency and Features of Classical Cohesinopathies.
A 5-year-old boy had developmental delay and intellectual disability with feeding difficulties, alongside hypoglycemia, recurrent fever, and immunodeficiency.
Malignant pertussis in a young infant.
A young infant presented with malignant pertussis, characterized by extreme leucocytosis and respiratory failure, alongside additional bloodstream infections during hospitalization.
Erythema ab igne in a paediatric patient: an unexpected cause.
A mid-childhood boy presented with an abdominal rash, initially thought to indicate liver injury after minor trauma. Despite unremarkable blood tests and imaging, the rash progressed with skin breakdown.
Successful bridge to heart transplantation in a pediatric patient with biventricular heart failure associated with Barth syndrome: a case report.
A one-year-old boy with Barth syndrome presented in cardiogenic shock due to severe biventricular heart failure. He received emergency biventricular assist device support, with innovative management of the right…
Gastric Residual Volume Assessment in Critically Ill Children: The GASTRIC-PICU Randomized Clinical Trial.
The GASTRIC-PICU trial evaluated the impact of routine gastric residual volume (GRV) assessment on enteral feeding in critically ill children.
Triggering modalities to synchronise non-invasive respiratory support in preterm infants: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness of synchronised nasal intermittent positive pressure ventilation (sNIPPV) in preterm infants, comparing it to other non-invasive respiratory support…
One-Lung Ventilation in a Pediatric Tracheostomy Patient: A Case Report.
A 20-month-old male with congenital lobar emphysema required a right middle lobectomy. He was ventilator-dependent following previous surgeries, including a tracheostomy.
Tricuspidization of a unicuspid aortic valve in an adolescent using selective single-cusp replacement.
An adolescent with a unicuspid aortic valve exhibiting stenosis and regurgitation underwent a novel tricuspidization procedure.
Immunogenicity up to age 5 years following a single-dose or two-dose infant primary series of 10-valent or 13-valent pneumococcal conjugate vaccine each followed by a booster dose in South Africa: extended follow-up of a single-centre, open-label, non-inferiority, randomised controlled trial.
This study evaluated the long-term immunogenicity of single-dose (1+1) versus two-dose (2+1) schedules of 10-valent (PCV10) and 13-valent (PCV13) pneumococcal conjugate vaccines in South African infants.
Massive Upper Gastrointestinal Bleeding in an Adolescent Patient: A Case Report.
A 17-year-old boy with plaque psoriasis presented with copious hematemesis and hemodynamic instability. He received blood transfusion and was admitted to the pediatric intensive care unit.
Catheter salvage with antibiotic lock therapy for central venous port infection due to Pseudoxanthomonas sp. in a child with hemophilia B.
A 4-year-old boy with severe hemophilia B developed persistent bacteremia associated with an implanted central venous port.
Beyond da Vinci: a systematic review of next-generation multiport robotic platforms in pediatric surgery.
This systematic review evaluated the technical features and outcomes of next-generation multiport robotic platforms in pediatric surgery, focusing on 166 patients across six studies.
Ibuprofen versus acetaminophen for acute mild-to-moderate pain management in pediatric populations: a systematic review and meta-analysis of their efficacy.
This systematic review and meta-analysis evaluated the analgesic efficacy of ibuprofen versus acetaminophen in pediatric populations with acute mild-to-moderate pain.
Dysmorphic child with cone-shaped epiphyses: a diagnostic approach and novel trichorhinophalangeal syndrome gene variant.
A teenage girl presented with clinical and radiological features consistent with trichorhinophalangeal syndrome type I, characterized by short, deformed fingers and cone-shaped epiphyses.
Hypernatremia-associated rhabdomyolysis in paediatric traumatic brain injury.
A male adolescent with severe traumatic brain injury from a motorcycle accident developed severe hypernatremia (168 mEq/L) while receiving hypertonic solutions in the ICU.
Expediting a UNIVERSAL first-line regimen of a dolutegravir-emtricitabine-tenofovir alafenamide fixed-dose ratio for children living with HIV older than 4 weeks: a 24-week, open-label, single-arm, phase 1-2, pharmacokinetic, safety, and antiviral activity trial.
The UNIVERSAL1 trial evaluated the pharmacokinetics, safety, and antiviral activity of a fixed-dose combination of dolutegravir, emtricitabine, and tenofovir alafenamide in children aged 28 days to 10 years with HIV.
Vagus nerve stimulation in pediatric patients with Lennox-Gastaut syndrome: a systematic review.
This systematic review assessed the efficacy and safety of vagus nerve stimulation (VNS) for refractory Lennox-Gastaut syndrome in pediatric patients, drawing on observational studies and case series.
Pathogenicity of NUSAP1 Variants Is Defined by NMD-Escape: Evidence From Two Novel Cases and Systematic Population-Based Variant Analysis.
Two individuals with heterozygous de novo nonsense variants in the penultimate or last exon of NUSAP1 presented with early-onset refractory epilepsy, global developmental delay, congenital microcephaly, and a…
Multiple Bone Metastases Exhibiting Exceptionally High 18 F-MFBG Uptake Exceeding Physiological Bladder Activity in a Patient With Neuroblastoma.
A 6-year-old boy with high-risk neuroblastoma underwent multimodal therapy and follow-up 18F-MFBG PET/CT for treatment response assessment.
Patient and Public Involvement and Engagement in Pediatric Health Research: A Systematic Review.
This systematic review examined patient and public involvement and engagement (PPIE) in pediatric health research, analyzing 37 studies.
Criteria for Safe Hospital Discharge in Bronchiolitis: A Systematic Review.
This systematic review evaluated discharge criteria for infants under 12 months with bronchiolitis, synthesizing evidence from two retrospective observational studies involving 2,697 patients.
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