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495 articles
June 202621
Anterior segment OCT, Schlemm's canal, and carotid-cavernous fistula: Reflections on a clinical case.
A 69-year-old man presented with diplopia and right-eye conjunctival injection with corkscrew vessels, proptosis, and sixth cranial nerve palsy. He was diagnosed with a right carotid-cavernous fistula.
Correcting photoreceptor diseases at their source: CRISPR strategies for cone-rod dystrophy and achromatopsia.
This systematic review evaluates CRISPR/Cas9 strategies for treating cone-rod dystrophy (CORD) and achromatopsia (ACHM) by analyzing preclinical studies.
Orbital manifestations of inflammatory bowel disease - a systematic review.
Extra-intestinal manifestations of inflammatory bowel disease (IBD) occur in 25-40% of patients; however, orbital involvement is rare and underreported.
Intraocular Pressure Changes Following Intraluminal Stent Removal From the Paul Glaucoma Implant: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of intraluminal stent removal from the Paul glaucoma implant on intraocular pressure (IOP) changes in 283 eyes.
The Role of Adjuvant Corneal Cross-linking in the Management of Infectious Keratitis: An OCT-Based Assessment Study.
This randomized controlled trial evaluated the impact of adjuvant corneal cross-linking (CXL) in 40 patients with infectious keratitis.
Postoperative hypotony after retinectomy in rhegmatogenous retinal detachment surgery: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence of postoperative hypotony following retinectomy in rhegmatogenous retinal detachment surgery, analyzing 33 studies with 2673 eyes.
Postoperative pain and wound healing following pediatric oral soft-tissue surgery: A network meta-analysis.
This network meta-analysis evaluated postoperative pain and wound healing in pediatric patients undergoing oral soft-tissue surgery using various tools, including scalpels and energy-based modalities.
Prenatal Ultrasonographic Detection of Bilateral Congenital Cataracts With Concurrent Mosaic Turner Syndrome: A Case Report.
A woman with a history of cataracts presented for prenatal ultrasound at 22 weeks gestation, where bilateral congenital cataracts were detected.
Congenital myasthenic syndrome due to novel GFPT1 variant presenting with head drop and visual impairment: A case report.
A 5-year-old boy had hypotonia, progressive weakness with head drop, cognitive delay, and visual impairment. Neuroimaging showed white matter abnormalities and atrophy of the corpus callosum and cerebellum.
Chronic papillary conjunctivitis as a novel ocular manifestation of Rickettsia felis infection: A case report.
A 27-year-old man presented with a 4-year history of unilateral papillary conjunctivitis that did not respond to multiple antibiotic treatments. Examination revealed significant conjunctival changes and eyelid laxity.
Cystic Panfolliculoma of the Eyelid.
A woman in her early 90s had a painless, crateriform lesion at the left eyelid and lower eyebrow that had worsened over approximately 1 year, fluctuated in size, and sometimes shed a scab with drainage.
Histiocytic Sarcoma of the Eyelid: An Uncommon Presentation of a Rare Neoplasm.
An 80-year-old man presented with a rapidly enlarging lesion of the left lower eyelid over 4 months. Shave biopsy showed histologic and immunophenotypic features most consistent with morphologically low-grade…
Population-Level Teleretinal Screening Bulk Orders to Improve Diabetic Retinopathy Screening Rates: A Randomized Quality Improvement Trial.
This randomized controlled trial assessed the effect of teleretinal screening bulk orders on diabetic retinopathy (DR) screening rates among patients with type 2 diabetes.
Orbital involvement in sickle cell disease: A systematic review.
This systematic review analyzed 76 cases of orbital involvement in sickle cell disease (SCD) from 53 studies. Predominantly affecting males with an average age of 13.2 years, the review highlighted that 6.6% presented…
Gildeuretinol Acetate versus Placebo for Geographic Atrophy Secondary to Age-Related Macular Degeneration: The Study of ALK-001 in Geographic Atrophy Randomized Clinical Trial.
This randomized, placebo-controlled trial evaluated gildeuretinol acetate in 198 participants aged ≥60 years with geographic atrophy (GA) over 24 months.
First Case of Congenital Toxoplasmosis After Maternal Reinfection in Colombia: Serotyping Evidence of Reinfection by Different Strains.
An immunocompetent woman with prior Toxoplasma IgG positivity later had both IgG and IgM detected four months before pregnancy.
Cancer and glaucoma: A systematic review.
This systematic review examined the relationship between glaucoma and cancer, analyzing 44 studies. It found that 18 studies reported increased glaucoma prevalence in cancer patients, while 15 studies indicated that…
Corneal epithelium remodelling after Laser refractive surgery with perioperative intense pulsed light treatment.
This randomized, controlled, triple-masked trial evaluated perioperative intense pulsed light (IPL) versus placebo in 61 patients undergoing femtosecond LASIK or keratorefractive lenticule extraction.
Vitrectomy Versus Observation for Lamellar Macular Holes With Epiretinal Proliferation: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the visual and anatomical outcomes of vitrectomy versus observation in patients with lamellar macular holes and epiretinal proliferation.
THRIVE: A Phase 3, Randomized, Double-Masked, Placebo-Controlled Study of Veligrotug for Active Thyroid Eye Disease.
The THRIVE study evaluated the efficacy and safety of veligrotug, a monoclonal antibody, in adults with moderate-to-severe active thyroid eye disease (TED) in a phase 3 randomized controlled trial.
Risk of Retinal Detachment After Intravitreal Injection of Anti-VEGF: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the risk of retinal detachment (RD) following intravitreal injections of anti-VEGF agents across various conditions.
May 20263
An Extremely Rare and Devastating Complication of Penetrating Keratoplasty: Postoperative Endophthalmitis Because of Carbapenem-Resistant Klebsiella pneumoniae.
A 69-year-old woman developed early-onset endophthalmitis due to carbapenem-resistant Klebsiella pneumoniae following elective penetrating keratoplasty for bullous keratopathy.
Comprehensive proteomic meta-analysis identifies novel proteomics alterations in proliferative diabetic retinopathy.
This meta-analysis examined proteomic alterations in patients with proliferative diabetic retinopathy (PDR) by analyzing five datasets.
Intraoperative 5-Aminolevulinic Acid Fluorescence in Periocular Sebaceous Carcinoma: A Proof-of-Concept Case Report.
An 80-year-old man with biopsy-proven invasive sebaceous carcinoma involving the right upper eyelid and conjunctiva underwent planned orbital exenteration and sentinel lymph node biopsy.
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