Trending archive
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470 articles
June 20269
Sugammadex versus neostigmine for reversal of neuromuscular blockade and postoperative pulmonary complications (SNaPP): an international, randomised, controlled, phase 4 trial.
This phase 4, multicenter, randomized controlled trial evaluated the effects of sugammadex versus neostigmine on postoperative pulmonary complications in adults undergoing abdominal or thoracic surgery.
Patient-reported outcome measures-guided peri-operative care versus standard of care in postoperative recovery: Randomised controlled trial in orthopaedic surgery.
This single-centre, prospective, pragmatic randomised controlled trial compared PROMs-guided peri-operative care with usual care in 280 adults undergoing osteoarticular surgery at a French university hospital.
Application of SPI-guided analgesia in laparoscopic gynecologic surgery: a randomized controlled trial evaluating the remifentanil-sparing effect and predictive value of time-weighted SPI.
This randomized controlled trial evaluated the opioid-sparing effect of Surgical Pleth Index (SPI)-guided analgesia in 61 patients undergoing laparoscopic gynecologic surgery.
Intermittent Bolus versus Continuous Infusion Erector Spinae Catheters for Median Sternotomy Incisions:A Randomized Controlled Trial.
This randomized controlled trial evaluated the analgesic efficacy of programmed intermittent boluses (PIB) versus continuous infusion of ropivacaine via erector spinae plane catheters in adults undergoing open heart…
Do Perineural Dexamethasone and Dexmedetomidine Improve Analgesia and Inflammatory Response After Lumbar Spine Surgery?
This prospective, randomized, triple-blinded controlled trial compared erector spinae plane blocks (ESPB) with ropivacaine alone or with dexamethasone or dexmedetomidine in adults undergoing posterior lumbar…
Higher versus Routine Intraoperative Blood Pressure Targets in Noncardiac Surgery: A Systematic Review and Meta-analysis with Trial Sequential Analysis of Randomized Trials.
This systematic review and meta-analysis evaluated the impact of higher intraoperative blood pressure targets on postoperative outcomes in 15 trials involving 15,603 patients undergoing elective noncardiac surgery.
Maternal and fetal outcomes of spinal cord stimulation in pregnancy: systematic review with descriptive meta-analysis.
This systematic review and meta-analysis evaluated maternal and fetal outcomes in 31 pregnant patients with spinal cord stimulation (SCS) devices.
Impact of Intravenous Lidocaine, Dexmedetomidine, and Intrathecal Morphine on Metastasis-Related Biomarkers and Cellular Immune Profiles in Colorectal Surgery: A Prospective, Randomized Controlled Trial.
This prospective, randomized controlled trial evaluated the effects of intravenous lidocaine, dexmedetomidine, and intrathecal morphine on metastasis-related biomarkers and immune profiles in 114 adults undergoing…
Percutaneous peripheral nerve stimulation for shoulder pain: A systematic review of randomized controlled trials.
This PRISMA-guided systematic review assessed randomized controlled trials of percutaneous peripheral nerve stimulation (PNS)-related interventions for postoperative and other shoulder pain presentations.
May 202615
Safety and tolerance of oral ketamine: A systematic review.
This systematic review assessed the safety and tolerability of oral ketamine across various clinical populations, including adults and children.
Half-dose neostigmine and low dose sugammadex as a reversal agent for vecuronium: A pilot randomized trial.
This pilot randomised trial compared reversal strategies for vecuronium-induced neuromuscular blockade in 80 patients undergoing elective urinary surgery under general anaesthesia.
The Effect of Mandala Art Therapy on Anxiety and Pain in Patients Undergoing Total Hip Arthroplasty: A Randomized Controlled Trial.
This randomized controlled trial evaluated the impact of mandala art therapy on anxiety and pain in 84 patients undergoing total hip arthroplasty.
Dexmedetomidine Preemptive Analgesia on Intra- and Postoperative Pain in Noncardiac Surgery: A Randomized, Double-Blind, Controlled Study.
This single-center, double-blind randomized controlled trial evaluated preemptive intravenous dexmedetomidine in 220 patients undergoing noncardiac surgery.
Intraoperative low-dose ketamine for postoperative pain outcomes in opioid-naïve patients: A systematic review and meta-analysis.
This pre-registered systematic review and meta-analysis assessed intraoperative low-dose ketamine for postoperative pain in opioid-naïve patients, pooling 18 randomised controlled trials with 1339 participants.
Opioid-free versus opioid-based anesthesia for postoperative nausea and vomiting in laparoscopic cholecystectomy: A Systematic Review with Meta-Analysis, Meta-Regression and Trial Sequential Analysis.
This systematic review and meta-analysis pooled 10 randomized controlled trials involving 1065 patients undergoing laparoscopic cholecystectomy to compare opioid-free with opioid-based anesthesia.
Effect of dexmedetomidine as an adjuvant in erector spinae plane block on postoperative analgesia in thoracolumbar spine surgery with an opioid free anaesthesia technique: A prospective randomized clinical trial.
This randomized controlled trial evaluated the efficacy of dexmedetomidine as an adjuvant in erector spinae plane block for postoperative analgesia in 40 patients undergoing thoracolumbar spine surgery with opioid-free…
Prophylactic interventions to prevent rebound pain after peripheral nerve block in adults: a systematic review and network meta-analysis of randomised controlled trials.
This systematic review and network meta-analysis evaluated pharmacological strategies to prevent rebound pain after peripheral nerve blocks in 2130 adults.
The Effect of Acupressure on Procedural Pain, Anxiety, and Hemodynamic Parameters During Chest Tube Removal in Open-Heart Surgery Patients: A Randomized Sham-Controlled Study.
This randomized sham-controlled trial investigated the effects of acupressure on procedural pain and anxiety during chest tube removal in 68 open-heart surgery patients.
Does Use of a Soft Endotracheal Tube Reduce Epistaxis During Pediatric Oral and Maxillofacial Procedures?
This randomized controlled trial evaluated the incidence of epistaxis in 96 pediatric patients undergoing dental procedures with either spiral or RAE nasal endotracheal tubes.
Proportional Assist Ventilation and Respiratory Effort Monitoring During Transition to Spontaneous Breathing.
This physiological randomized crossover study assessed whether the PAV+ work-of-breathing bar accurately reflects respiratory effort in 35 subjects being weaned from mechanical ventilation.
Ketamine-based ICU sedation and patient-centered outcomes: A systematic review and meta-analysis of mechanical ventilation duration, ICU length of stay, and delirium.
This systematic review and meta-analysis evaluated the effects of ketamine-based sedation on ICU outcomes in 903 patients. It found that ketamine significantly reduced ICU length of stay (MD: -0.86; 95% CI: -1.51…
Dental and Dentofacial Findings in a Child With CHOPS Syndrome Managed Under General Anesthesia.
An 11-year-old male with CHOPS syndrome presented with multiple dental caries. Examination revealed midface hypoplasia, coarse facial features, and intraoral findings including enamel hypoplasia and a high palatal vault.
Goal-Directed Hemodynamic Therapy in Deceased-Donor Kidney Transplantation: A Prospective Paired-Kidney Study.
This randomized controlled trial evaluated goal-directed hemodynamic therapy (GDHT) using FloTrac in 40 patients undergoing deceased-donor kidney transplantation.
Goal-directed perfusion strategy in urgent repair of Post-Myocardial infarction left ventricular free wall rupture: A case report.
A 45-year-old woman presented with acute anterior ST-elevation myocardial infarction complicated by left ventricular free wall rupture and cardiogenic shock; her preoperative lactate was 11.1 mmol/L.
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