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557 articles

August 202620

Clinical ResearchOncology (Medical)

Daily low-dose carboplatin or weekly carboplatin plus nab-paclitaxel for concurrent chemoradiotherapy in older patients with locally advanced non-small cell lung cancer (JCOG1914): A randomized phase 3 trial.

This randomized phase 3 trial evaluated daily low-dose carboplatin versus weekly carboplatin plus nab-paclitaxel in patients aged ≥75 years with locally advanced non-small cell lung cancer (LA-NSCLC).

Lung CancerAug 14, 2026Read summary
Clinical ResearchPulmonology

Long-Acting Muscarinic Antagonist as an Alternative to Inhaled Corticosteroids in Type 2-Low Mild Asthma: A Randomized Crossover Non-inferiority Trial.

This multicenter, pragmatic, randomized, open-label crossover non-inferiority trial compared 6 months of long-acting muscarinic antagonist (LAMA) monotherapy with 6 months of inhaled corticosteroid (ICS) therapy in…

J Allergy Clin Immunol PractAug 14, 2026Read summary
Clinical ResearchNuclear MedicineOpen access

68 Ga-granzyme B ( 68 Ga-NOTA-GSI) PET/CT for predicting immunotherapy response and progression free survival in NSCLC.

This prospective, single-centre trial evaluated ⁶⁸Ga-NOTA-GSI PET/CT after two treatment cycles in 41 patients with stage IIIB/IV non-small cell lung cancer receiving immunotherapy.

Eur J Nucl Med Mol ImagingAug 14, 2026Read summary
Clinical ResearchOncology (Medical)

Patient-reported outcomes with tarlatamab in extensive-stage small cell lung cancer after platinum-based chemotherapy: results from the phase 3 DeLLphi-304 trial.

The phase 3 DeLLphi-304 trial evaluated patient-reported outcomes (PROs) in adults with extensive-stage small cell lung cancer (ES-SCLC) receiving tarlatamab versus standard-of-care chemotherapy after platinum-based…

Lung CancerAug 13, 2026Read summary
Clinical ResearchOncology (Medical)

A phase 2 study of encorafenib in combination with binimetinib for Chinese participants with BRAF V600E mutated metastatic non-small cell lung cancer: Results from the OCEAN II study.

The OCEAN II study, a phase 2 clinical trial, evaluated the efficacy and safety of encorafenib combined with binimetinib in 63 Chinese participants with BRAF V600E-mutated metastatic non-small cell lung cancer.

Lung CancerAug 13, 2026Read summary
Clinical ResearchPulmonology

Symptoms and treatment response to florensocatib and inhaled tobramycin in bronchiectasis: Post hoc analysis of two randomized trials.

This post hoc analysis of two randomized trials (SAVE-BE and TORNASOL) evaluated the impact of baseline symptom burden on treatment responses to florensocatib and inhaled tobramycin in patients with bronchiectasis.

Cell Rep MedAug 13, 2026Read summary
Clinical ResearchPulmonologyOpen access

Impact of respiratory muscle training on sleep disordered breathing in people with tetraplegia: a sub-analysis of a randomised controlled trial.

This sub-analysis of a randomised controlled trial examined whether six weeks of supervised respiratory muscle training (RMT) changed sleep-disordered breathing (SDB) or daytime sleepiness in adults with tetraplegia.

Spinal CordAug 13, 2026Read summary
Clinical ResearchPulmonology

Single-slice Functional Lung MRI During Metronome-Paced Tachypnea Detects Changes in Regional Ventilation Dynamics After a Single Dose of Dual Bronchodilator Treatment in COPD.

This randomized controlled trial evaluated the effects of dual bronchodilator treatment on regional ventilation dynamics in patients with stable COPD using single-slice PREFUL MRI during metronome-paced tachypnea (MPT).

COPDAug 12, 2026Read summary
Clinical ResearchPulmonology

MicroRNAs in IPF and lung cancer: convergent and divergent mechanisms: a systematic review.

This systematic review examines the role of microRNAs (miRNAs) in idiopathic pulmonary fibrosis (IPF) and lung cancer (LC), highlighting shared and distinct mechanisms.

Am J Physiol Lung Cell Mol PhysiolAug 12, 2026Read summary
Case ReportPulmonologyOpen access

Fatal pulmonary thromboembolism associated with excessive nitrous oxide consumption over several weeks.

A man in his early twenties was hospitalized with acute nitrous oxide intoxication, vitamin B12 deficiency and anaemia. Two weeks later, he was found dead; empty nitrous oxide cartridges were present, and his mother…

Int J Legal MedAug 12, 2026Read case
Clinical ResearchPulmonology

Interventions with a significant mortality difference in acute respiratory distress syndrome: A systematic review and comparison with Guidelines.

This systematic review analyzed 33 randomized controlled trials (RCTs) to compare interventions with significant mortality differences in acute respiratory distress syndrome (ARDS) against European and American…

J Crit CareAug 11, 2026Read summary
Clinical ResearchOncology (Medical)

Stage shift, histological differentiation, and survival patterns of lung squamous cell carcinoma versus adenocarcinoma in low-dose CT screening.

This randomized controlled trial compared stage shift, histological differentiation, and survival patterns between lung squamous cell carcinoma (LUSC) and adenocarcinoma (LUAD) in low-dose CT (LDCT) screening.

Cancer EpidemiolAug 11, 2026Read summary
Case ReportInfectious DiseasesOpen access

Chronic Melioidosis Presenting with Pneumonia, Empyema, and Splenic Abscess.

A patient with recurrent chest pain, cough, and abdominal discomfort over 11 months had initially been treated for a common bacterial infection.

Am J Trop Med HygAug 11, 2026Read case
Clinical ResearchInfectious Diseases

Diagnostic accuracy of bronchoalveolar lavage fluid-based testing for pulmonary cryptococcosis: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the diagnostic accuracy of bronchoalveolar lavage fluid (BALF)-based testing for pulmonary cryptococcosis.

Diagn Microbiol Infect DisAug 10, 2026Read summary
Clinical ResearchPulmonology

Feedback-enhanced electronic monitoring for asthma inhaler adherence: A systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis of randomized controlled trials assessed feedback-enhanced electronic inhaler monitoring versus standard care in people with asthma.

Int J Nurs StudAug 10, 2026Read summary
Clinical ResearchPulmonology

Pulmonary Rehabilitation Combining Education and Exercise Training in Adults With Asthma: A Systematic Review and Meta-analysis of Clinical Outcomes and Program Duration Effects.

This systematic review and meta-analysis assessed pulmonary rehabilitation (PR) that included education and exercise training in adults with asthma, drawing on randomized clinical trials.

J Allergy Clin Immunol PractAug 8, 2026Read summary
Clinical ResearchInternal Medicine (General)Open access

Rethinking Muscle Wasting in Critical Illness: A Systematic Review and Meta-Analysis of Myofiber Size and Protein Turnover.

This systematic review and meta-analysis examined skeletal muscle dysfunction in adults with critical illness, analyzing myofiber size and protein turnover.

Crit Care MedAug 7, 2026Read summary
Clinical ResearchOncology (Medical)

SKYSCRAPER-03: a phase III study of tiragolumab plus atezolizumab versus durvalumab in locally advanced, unresectable, stage III NSCLC after platinum-based concurrent chemoradiation.

SKYSCRAPER-03 was a phase III, open-label, randomized trial comparing consolidation tiragolumab plus atezolizumab with durvalumab after platinum-based concurrent chemoradiation in patients with locally advanced…

Ann OncolAug 6, 2026Read summary
Case ReportNuclear Medicine

Focal Vascular Photopenia as a Metabolic Signature of Pulmonary Embolism on AI-Enhanced 18 F-FDG PET/CT.

Artificial intelligence (AI)-enhanced reconstruction of 18 F-FDG PET/CT may reveal important metabolic patterns barely visible on standard reconstructions.

Clin Nucl MedAug 4, 2026Read case
Clinical ResearchCardiology

Pulmonary Arterial Hypertension-Targeted Therapy for Pulmonary Hypertension Associated With Left Heart Disease: Bayesian and Frequentist Meta-Analysis of Randomized Controlled Trials.

This Bayesian and frequentist meta-analysis assessed pulmonary arterial hypertension (PAH)-targeted therapy versus placebo in patients with pulmonary hypertension associated with left heart disease (PH-LHD).

Am J CardiolAug 4, 2026Read summary

July 20264

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