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485 articles

July 202624

Case ReportMedical Genetics

Clinical and population genetic insights into primary complement component 2 (C2) deficiency: A founder variant in Ashkenazi Jews.

A 14-year-old Ashkenazi Jewish boy presented with bullous cutaneous lupus erythematosus and lupus nephritis. His diagnosis of complement component 2 deficiency (C2D) was influenced by a family history of fatal…

Clin ImmunolJul 28, 2026Read case
Clinical ResearchEndocrinologyOpen access

Impact of Albuminuria-Lowering Treatments on Cardiovascular Predictive Ceramides in Diabetes: Post Hoc Analysis of the ROTATE Trials.

This post hoc analysis of the ROTATE trials evaluated the impact of four albuminuria-lowering drugs on cardiovascular-related ceramides in 63 adults with diabetes.

Diabetes Obes MetabJul 28, 2026Read summary
Clinical ResearchNephrologyOpen access

Adherence to the Mediterranean diet and its effects on the onset and progression of diabetic nephropathy: a systematic review.

This systematic review evaluated the relationship between adherence to the Mediterranean diet (MD) and the onset and progression of diabetic nephropathy (DN) in adults with diabetes.

Ren FailJul 27, 2026Read summary
Clinical ResearchNephrology

Efficacy and safety of selective aldosterone synthase inhibitors for blood pressure reduction in patients with CKD: a meta-analysis of randomized controlled trials.

This meta-analysis evaluated the efficacy and safety of selective aldosterone synthase inhibitors (ASIs) for blood pressure reduction in patients with chronic kidney disease (CKD).

J HypertensJul 27, 2026Read summary
Case ReportPediatrics

Nursing care of an infant with atypical hemolytic uremic syndrome complicated by spontaneous bullous rupture and dystrophic wound calcification: A case report.

An 8-month-old male infant with atypical hemolytic uremic syndrome (aHUS) developed spontaneous bullous rupture and dystrophic wound calcification after one month of treatment.

J Pediatr NursJul 27, 2026Read case
Clinical ResearchMedical Genetics

The Expanding Phenotypic Spectrum of COL4A1- and COL4A2-Related Disorders: A Systematic Review.

This systematic review analyzed 99 articles to characterize the phenotypic spectrum of COL4A1- and COL4A2-related disorders in 367 patients.

Pediatr NeurolJul 27, 2026Read summary
Case ReportNephrology

Case Report: Falsely Elevated Tacrolimus Concentrations in a Kidney Transplant Recipient.

A 67-year-old female kidney transplant recipient exhibited persistently elevated tacrolimus concentrations despite discontinuation of the drug.

Transplant ProcJul 26, 2026Read case
Case ReportInfectious Diseases

Klebsiella pneumoniae septic pulmonary embolism from renal vein thrombosis.

A 47-year-old woman with untreated diabetes presented with urinary symptoms, fever, abdominal pain, and hypoxemia. Blood and urine cultures confirmed Klebsiella pneumoniae, with persistent bacteremia despite meropenem…

Int J Infect DisJul 26, 2026Read case
Clinical ResearchGastroenterologyOpen access

Effects of age, sex, and renal function on bowel movement-improving effects of Bifidobacterium bifidum G9-1 on constipation in patients with type 2 diabetes mellitus and chronic kidney disease: A prespecified subgroup analysis of the BIRDIE study.

This prespecified subgroup analysis of the BIRDIE study evaluated the impact of age, sex, and renal function on the efficacy of Bifidobacterium bifidum G9-1 for constipation in patients with type 2 diabetes and chronic…

J Diabetes InvestigJul 26, 2026Read summary
Case ReportNephrology

Diagnostic pitfall: NSAID-induced membranous nephropathy with PLA2R positivity, IgG1-predominant deposits, C1q positivity, and concurrent acute interstitial nephritis-A case report.

A 71-year-old woman with long-term unsupervised NSAID use for polymyalgia rheumatica presented with recurrent nephrotic syndrome and acute kidney injury.

Clin Chim ActaJul 26, 2026Read case
Clinical ResearchNephrology

Renal Impairment and Age-Related Macular Degeneration: A Comprehensive Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined observational and Mendelian randomization evidence on renal impairment and age-related macular degeneration (AMD).

Am J OphthalmolJul 25, 2026Read summary
Clinical ResearchNephrology

Acute Kidney Injury After Intensive Blood Pressure Lowering Following Successful Endovascular Thrombectomy.

This randomized controlled trial analyzed the impact of intensive blood pressure management on acute kidney injury (AKI) in 287 patients with acute ischemic stroke post-endovascular thrombectomy.

StrokeJul 24, 2026Read summary
Case ReportNephrology

Long-Term Clinical Course of COL4A1-Associated Nephropathy and Assessment of α1 Chain of Type IV Collagen Expression in Kidney Biopsy Specimens: A Case Report.

A 39-year-old man with a heterozygous p.G1239R COL4A1 variant presented with persistent microscopic hematuria and a gradual decline in estimated glomerular filtration rate over 10 years.

Am J Kidney DisJul 24, 2026Read case
Case ReportMedical Genetics

Diagnosing Mendelian Kidney Disease: Hidden Niches in the (Kidney) Genome.

A family with a history of autosomal dominant kidney disease presented with renal failure in middle adulthood. Genetic analysis revealed the index patient had both autosomal dominant polycystic kidney disease (ADPKD)…

Am J Kidney DisJul 24, 2026Read case
Clinical ResearchNephrology

Circulating KIM-1 and survival outcomes in renal cell carcinoma: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prognostic significance of circulating kidney injury molecule-1 (KIM-1) in renal cell carcinoma (RCC) across 2,415 patients from 7 studies.

Urol OncolJul 23, 2026Read summary
Clinical ResearchNephrologyOpen access

Regional Citrate Anticoagulation Versus No Anticoagulation During Continuous Renal Replacement Therapy in Critically Ill Patients at High Risk of Bleeding: A Meta-analysis of Randomized Controlled Trials.

This meta-analysis evaluated regional citrate anticoagulation (RCA) versus no anticoagulation (NA) during continuous renal replacement therapy (CRRT) in critically ill patients at high bleeding risk.

Adv TherJul 23, 2026Read summary
Case ReportCardiology

Heart Failure in Young Women with Systemic Lupus Erythematosus.

Two women aged 23 and 36 years with newly diagnosed systemic lupus erythematosus presented with acute decompensated heart failure, dyspnea, edema, and cardiomegaly.

Ann Afr MedJul 23, 2026Read case
Case ReportInfectious Diseases

Chronic hepatitis E and Medicopsis romeroi coinfection in a Canadian renal transplant recipient: a case report.

A Canadian renal transplant recipient presented with chronic hepatitis E virus infection and subcutaneous phaeohyphomycosis caused by Medicopsis romeroi.

Diagn Microbiol Infect DisJul 22, 2026Read case
Clinical ResearchUrology

Efficacy and Tolerability of Overnight Bladder Drainage Post Posterior Urethral Valve Ablation on Upper and Lower Urinary Tracts: A Randomized Controlled Trial.

This randomized controlled trial assessed overnight bladder drainage (OBD) in boys with persistent hydronephrosis and unfavorable bladder dynamics after endoscopic posterior urethral valve ablation.

J UrolJul 21, 2026Read summary
Case ReportOncology (Medical)

Multifocal Hepatic Epstein-Barr Virus-Associated Smooth Muscle Tumor Mimicking Posttransplant Lymphoproliferative Disorder in a Renal Allograft Recipient.

A 19-year-old renal transplant recipient presented with abdominal symptoms suggestive of posttransplant lymphoproliferative disorder (PTLD). Imaging with 18F-FDG PET/CT revealed multiple hypermetabolic liver lesions.

Clin Nucl MedJul 20, 2026Read case
Case ReportEndocrinology

Variability in magnitude and direction of discordance between continuous glucose monitoring (CGM) metrics and traditional biomarkers in patients with diabetes and end-stage kidney disease (ESKD): A case series.

Four patients with diabetes and end-stage kidney disease exhibited significant discordance between glycated hemoglobin A1c (HbA1c) and continuous glucose monitoring (CGM) metrics.

Diabetes Res Clin PractJul 18, 2026Read case
Clinical ResearchCardiology

Home blood pressure telemonitoring reveals race-specific patterns of target organ damage.

This multicenter randomized controlled trial examined racial differences in target organ damage (TOD) among high-risk Black and White patients aged 55-75 with home blood pressure monitoring.

J HypertensJul 17, 2026Read summary
Clinical ResearchNephrology

Time in Target Range for Hemoglobin A 1c and Systolic Blood Pressure: Association With Adverse Kidney Events.

This observational cohort study analyzed data from 6,542 participants in the ACCORD trial to evaluate the association of time in target range (TTR) for hemoglobin A1c (HbA1c) and systolic blood pressure (SBP) with…

Am J Kidney DisJul 17, 2026Read summary
Clinical ResearchInternal Medicine (General)Open access

Effects on mortality of different blood purification techniques in sepsis patients: an umbrella review of systematic reviews and meta-analyses.

This umbrella review analyzed 42 systematic reviews and meta-analyses to assess the impact of various extracorporeal blood purification techniques on mortality in sepsis patients.

Ren FailJul 16, 2026Read summary

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