Trending archive
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1602 articles
November 202624
Socio-economic status, cardiovascular risk factors, and coronary atherosclerosis: a SCOT-HEART trial analysis.
This post-hoc analysis of a multicentre randomised trial examined socioeconomic status (SES) in relation to coronary CT angiography (CCTA) plaque features, management, and cardiovascular outcomes.
Clinical Reasoning: A 55-Year-Old Woman With a Hyperkinetic Movement Disorder, External Ophthalmoplegia, and Myopathy.
A 55-year-old woman was evaluated for an 8-year history of hyperkinetic movements. Her examination and clinical picture also included mild ataxia, spasticity in the lower limbs, external ophthalmoplegia, and myopathy.
Predictors and prognostic impact of spontaneous portal vein thrombosis recanalization in cirrhosis: An individual patient data meta-analysis.
This individual patient data meta-analysis pooled cohort studies of patients with cirrhosis and portal vein thrombosis (PVT) who were not receiving anticoagulation.
ID-SCAN: a functional MRI protocol for neurophenomenological phenotyping of dissociative identity disorder without trauma provocation.
A woman with dissociative identity disorder and persistent co-consciousness between two identity-agents completed ID-SCAN, a functional MRI protocol that did not use trauma provocation.
Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.
This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…
Imaging-Based AI for Predicting Pathological Complete Response in Esophageal Cancer After Neoadjuvant Therapy: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed imaging-based AI models for predicting pathological complete response after neoadjuvant therapy for esophageal cancer, separating internal from external validation.
Coracoid Process Osteochondroma: Diagnostic Considerations and Detailed Approach for Management: Case Report and Literature Review.
A 21-year-old woman was found to have an osteochondroma arising from the tip of the coracoid process. The report describes preoperative clinical assessment and radiological investigation, with histopathological…
Intimate partner violence against women in Ethiopia: An umbrella review of systematic reviews and meta-analyses.
This umbrella review and random-effects meta-analysis synthesized six systematic reviews and meta-analyses, covering 80 primary studies and 43,785 women in Ethiopia, to estimate intimate partner violence (IPV)…
Acute Ethylene Glycol Poisoning Following Accidental Mineral Oil Ingestion With Severe Metabolic Acidosis, Acute Kidney Injury, Respiratory Failure, and Delayed Neurological Sequelae: A Case Report.
A 57-year-old man became dizzy, vomited, and developed altered consciousness progressing to coma after accidentally ingesting mineral oil containing ethylene glycol.
Digital Health Interventions for Pregnancy- and Childbirth-Related Posttraumatic Stress Disorder Symptoms in Postpartum Women: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled randomized controlled trials of digital health interventions for postpartum women who had experienced pregnancy- or childbirth-related trauma.
Home-Based, Digitally Assisted Dyadic Tai Chi Intervention for Patients With Chronic Heart Failure and Their Caregivers: Development of an Intervention and Pilot Randomized Controlled Trial.
This sequential, multiphase study developed a home-based, digitally assisted tai chi programme for people with chronic heart failure (CHF) and their caregivers, then evaluated it in a single-centre, assessor-blinded…
Postoperative Tumor-Informed Circulating Tumor DNA Status for Molecular Residual Disease Detection After Curative-Intent Resection of Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled observational evidence on postoperative tumor-informed circulating tumor DNA (ctDNA) as a marker of molecular residual disease after curative-intent resection of…
Polyamine Dysregulation in Metabolic Dysfunction-associated Steatotic Liver Disease: a Systematic Review of Human Observational Evidence.
This systematic review evaluated human observational evidence linking polyamines with MASLD severity and related hepatic or metabolic outcomes.
The unseen risk: a systematic review of the incidence, management, and outcomes of the trigeminocardiac reflex in skull-base surgery.
This PRISMA-guided systematic review synthesized reports of intraoperative trigeminocardiac reflex (TCR) during skull-base and adjacent neurosurgical procedures.
Effects on Sleep Quality and Bioelectrical Parameters of Cellular Health After Administration of a Plant Protein Supplement Combined with Ashwagandha and Rhodiola: A Randomized Controlled Trial.
This randomized, double-blind, placebo-controlled trial tested 30 days of plant protein combined with ashwagandha and rhodiola in adults aged 35–70 years. Of 100 participants assigned, 61 completed sleep assessments.
Conservative versus surgical management of traumatic acute subdural hematoma: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared surgical with conservative management of traumatic acute subdural hematoma in adults.
Measles-like hypermutation of a Newcastle disease virus drives fatal encephalitis during BCMA × CD3 T-cell-redirecting immunotherapy.
A patient with multiple myeloma receiving maintenance teclistamab, daratumumab, and lenalidomide developed rapidly progressive brainstem-cerebellar encephalitis.
Efficacy and safety of middle meningeal artery embolisation for chronic subdural haematoma: a systematic review and meta-analysis of randomised controlled trials.
This PRISMA-compliant systematic review and meta-analysis pooled randomised controlled trials comparing middle meningeal artery embolisation (MMAE)-based treatment with standard management in adults with radiologically…
Differential effects of pea protein isolate, pea protein concentrate, and whey protein isolate supplementation on gut microbiota and metabolic markers in healthy adults: a 3-arm parallel randomised intervention.
This double-blind, three-arm randomised dietary intervention compared four weeks of pea protein concentrate (PPC), pea protein isolate (PPI), or whey protein isolate (WPI) supplementation in healthy adults.
Efficacy and safety of selective orexin 2 receptor agonists in narcolepsy type 1: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis pooled randomized, double-blind, placebo-controlled trials of oral selective orexin 2 receptor agonists in people with narcolepsy type 1.
Alfred Kocher technique for prevention of patient-prosthesis mismatch in paediatric patients.
A 7-year-old girl requiring aortic valve replacement had a functionally unicuspid aortic valve. Although the Ross procedure is generally favored in children, an intraoperative bicuspid pulmonary valve made durable…
Optimizing survival and long-term outcomes in complex pediatric digital amputations: a case report with a 6.5-year follow-up.
A 1.5-year-old boy sustained complete thermal-crush amputations of the left index, middle, and ring fingers in an industrial sealer injury.
Regimens of vitamin D supplementation for women during pregnancy.
This updated Cochrane systematic review and meta-analysis assessed randomised trials of vitamin D regimens during pregnancy in women without pre-existing conditions or multiple pregnancies.
Poly (ADP-ribose) polymerase inhibitors (PARPi) for treating advanced epithelial ovarian cancer.
This Cochrane systematic review and meta-analysis assessed randomised trials of PARP inhibitors (PARPi) in women with newly diagnosed or recurrent epithelial ovarian cancer. It included 24 studies with 8961 participants.
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