Effects on Sleep Quality and Bioelectrical Parameters of Cellular Health After Administration of a Plant Protein Supplement Combined with Ashwagandha and Rhodiola: A Randomized Controlled Trial.
A Molina-López, A Leo-Romero, M Molina-López et al.
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In 30 seconds
This randomized, double-blind, placebo-controlled trial tested 30 days of plant protein combined with ashwagandha and rhodiola in adults aged 35–70 years. Of 100 participants assigned, 61 completed sleep assessments. Compared with placebo, the supplement group had a 58% improvement in total sleep score, described as a 3.7-fold greater improvement than placebo (p<0.001). Sleep difficulty and daytime sleepiness also decreased. Phase angle changes were minimal in both groups, and no adverse events were reported.
Key findings
- Total sleep score improved by 58% in the supplement group, a 3.7-fold greater improvement than placebo (p<0.001).
- Sleep difficulty decreased by 56% (p<0.001, d=0.91), and daytime sleepiness decreased by 60% (p<0.001, d=0.85).
- Phase angle changes were minimal in both groups; no adverse events were reported.
Why it matters
Sleep outcomes improved over the 30-day intervention, suggesting that this combined nutritional supplement may warrant further evaluation as an approach to sleep disturbance. The trial also found little change in the measured bioelectrical parameter, so the reported sleep benefits were not accompanied by a notable phase-angle change.
What to keep in mind
Sleep assessments were completed by 61 of 100 assigned participants, and bioimpedance analysis by 77. Follow-up was limited to the 30-day intervention.