Trending Now

Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedClinical ResearchPreventive Medicine / Public Health

2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.

Nutr RevNov 12, 2026

This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.

Why it matters

The guideline synthesizes evidence across multiple clinical and public health domains, indicating that dietary patterns may be relevant to prevention and outcomes across a broad range of non-communicable diseases.

Read summary

Also worth knowing

Clinical ResearchEndocrinology

Effects of Polyphenols on Gut Health and Inflammation in Overweight and Obese Populations: A Systematic Review and Meta-analysis of Dose, Duration, and Food Matrix.

This systematic review and meta-analysis assessed polyphenol interventions and gut microbiota and inflammatory biomarkers in people with overweight or obesity, drawing on 32 randomized controlled trials.

Nutr RevNov 12, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Whole-grain consumption and cardiometabolic risk: a meta-analysis of randomized trials.

This meta-analysis of randomized trials assessed how whole-grain intake affects cardiometabolic risk factors. It included 87 trials (101 publications) and estimated effects per 48 g/day increment in whole grains (dry…

Eur Heart JNov 10, 2026Read summary
Clinical ResearchNeurology

Severity-Based Triage for Direct Transportation to Nearest Comprehensive Stroke Center: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed prehospital bypass of the nearest stroke center for direct transport to a more distant comprehensive stroke center in patients with suspected stroke.

NeurologyNov 10, 2026Read summary
Clinical ResearchPsychiatry

Caring Contacts and Suicidality Among American Indian and Alaska Native Communities: A Randomized Clinical Trial.

The CARE study was a blinded, two-group randomized clinical trial of 709 American Indian and Alaska Native adults with active suicidality across five communities.

JAMA Netw OpenNov 2, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Efficacy of Technology-Augmented Behavioral Counseling for Risky Firearm Behaviors: A Randomized Clinical Trial.

This two-arm randomized clinical trial tested IntERact, a 30-day program combining telehealth behavioral counseling and tailored smartphone content, against enhanced usual care among 373 emergency department patients…

JAMA PediatrNov 1, 2026Read summary
Clinical ResearchPediatrics

Effect of a dietary behaviour change education intervention on iron status and linear growth in children aged 6 to 59 months: a cluster-randomised controlled trial in rural Ethiopia.

This cluster-randomised controlled trial evaluated community-based Dietary Intake Behaviour Education (DIBE) among children aged 6–59 months in rural central Ethiopia.

Prim Health Care Res DevNov 6, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Firearm Injury Prevention Bystander Intervention for Adolescents in Shooting Sports: A Cluster Randomized Clinical Trial.

This parallel cluster randomized clinical trial evaluated a 3-session, co-developed firearm injury prevention bystander curriculum among adolescents in US 4-H Shooting Sports clubs.

JAMA Health ForumNov 6, 2026Read summary
Clinical ResearchGeriatrics

Exercise and Nutritional Interventions for Muscle Strength, Physical Performance, and Body Composition Among Older Adults With Sarcopenia or Pre-Sarcopenia: A Network Meta-Analysis.

This network meta-analysis compared exercise, nutritional, and combined interventions with control strategies in older adults with sarcopenia or pre-sarcopenia.

Geriatr Gerontol IntNov 1, 2026Read summary
Clinical ResearchInfectious Diseases

Predictors of chronic arthralgia after chikungunya virus infection: a systematic review and meta-analysis.

This systematic review and meta-analysis examined predictors of chronic arthralgia, defined as lasting at least 3 months, after laboratory-confirmed chikungunya infection.

J Travel MedOct 30, 2026Read summary
Clinical ResearchGeriatricsOpen access

Prevalence of fall risk and fear of falling among older adults in the Middle East and North Africa: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis estimated fall risk and fear of falling among adults aged 60 years or older in the Middle East and North Africa (MENA).

J Glob HealthOct 30, 2026Read summary
Clinical ResearchCardiology

Cardiovascular disease and stroke prevention educational-behavioural programmes for culturally and/or linguistically diverse communities: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed cardiovascular disease (CVD) and stroke prevention educational-behavioural programmes for people from culturally and/or linguistically diverse (CALD) backgrounds.

Eur J Prev CardiolNov 11, 2026Read summary

Showing 12 of 71 publications that cleared our clinical screen in the last 14 days.

Looking for an earlier article?Everything that has appeared in Trending is in the archive.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.