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1602 articles
November 202624
Vitamin D receptor activator-associated calcium-alkali syndrome-like phenotype without calcium supplementation: a case series of seven patients.
A retrospective series identified seven elderly women receiving vitamin D receptor activators who developed hypercalcemia, bicarbonate of at least 26 mmol/L, and acute kidney injury, meeting the study’s operational…
Feasibility and tolerability of combining 6 Hz transcranial alternating current stimulation (tACS) at 3.2 mA and digital cognitive training in older adults with mild cognitive impairment.
This randomized-trial study evaluated feasibility and tolerability of five daily sessions of 6-Hz, 3.2-mA transcranial alternating current stimulation (tACS) during digital cognitive training (DCT) in older adults with…
De novo SETD5 missense variants in individuals with MRD23 cluster within the protein's SET domain.
SETD5 heterozygous loss-of-function (LoF) variants and 3p25.3 deletions containing the SETD5 gene cause intellectual developmental disorder, autosomal dominant 23 (MRD23).
Too good to be true? AI performance in CT-based urinary stone detection and classification: EAU endourology systematic review and diagnostic accuracy meta-analysis.
This systematic review and diagnostic accuracy meta-analysis assessed AI for detecting and classifying urinary stones on CT.
Sirolimus-induced improvement of immune dysregulation associated hepatosplenomegaly in common variable immunodeficiency: a case-based review.
A 50-year-old woman with common variable immunodeficiency (CVID), treated with regular intravenous immunoglobulin replacement, developed progressive hepatosplenomegaly, cytopenias, abdominal enlargement, dyspnea…
A phase 1 study of 4'-thio-2'-deoxycytidine in patients with solid tumors.
This phase 1 dose-escalation study evaluated oral 4′-thio-2′-deoxycytidine (TdCyd) in adults with advanced solid tumors. Twenty-seven patients received treatment on days 1–5 and 8–12 of 21-day cycles.
Intravesical BCG-induced granulomatous prostatitis mimicking prostate cancer in patients with non-muscle invasive bladder cancer: a systematic review.
This systematic review examined the clinical presentation of granulomatous prostatitis associated with intravesical BCG therapy for non-muscle-invasive bladder cancer.
Recovery after more than one month of dialysis in legionella-associated acute kidney injury: a case evaluated with gallium-67 scintigraphy and renal biopsy.
A 73-year-old man developed dialysis-dependent acute kidney injury during severe Legionella pneumonia. Although the infection resolved and antibiotics had been stopped, kidney injury persisted for more than a month.
Suction versus traditional ureteral access sheaths in retrograde intrarenal surgery: an updated systematic review and meta-analysis of stone-free rates and complications.
This updated systematic review and meta-analysis compared suction with traditional ureteral access sheaths during retrograde intrarenal surgery in adults.
Prevalence of generalized joint hypermobility, hypermobility spectrum disorders and Ehlers-Danlos syndrome: systematic review and meta-analysis.
This systematic review and meta-analysis assessed the prevalence of generalized joint hypermobility (GJH), hypermobility spectrum disorder (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS).
Descending aortic replacement after frozen elephant trunk: graft clamping and true-lumen anastomosis.
Second-stage descending aortic replacement after arch replacement with a frozen elephant trunk requires proximal control at a site that is often hostile to cross-clamping.
Carotid artery bypass and supraclavicular subclavian artery cannulation for cerebral malperfusion in aortic dissection.
A patient with acute type A aortic dissection extending from the aortic root to the right common femoral artery presented with cerebral malperfusion.
Off-pump subtotal pericardiectomy using ultrasonic aspirator in constrictive pericarditis.
A patient with constrictive pericarditis underwent subtotal pericardiectomy without cardiopulmonary bypass because of advanced age and underlying liver cirrhosis.
Spontaneous Colonic Migration of a Ventriculoperitoneal Shunt Catheter.
A 63-year-old man developed fever, somnolence, and elevated inflammatory markers 2.5 years after ventriculoperitoneal shunt placement.
Efficiency of Rescue Paramedic Hoist versus Underslung Antenna in Helicopter-Based Avalanche Searches: A Randomized Trial.
This randomized experimental field trial compared helicopter-based avalanche transceiver searches using an underslung antenna or a hoisted rescue paramedic with a handheld transceiver.
Dexmedetomidine with transition to oral clonidine for stabilization of refractory agitation: A case report.
A 45-year-old man with metastatic medullary thyroid carcinoma was admitted to a palliative care unit with severe opioid-refractory pain, delirium, and agitation that prevented palliative radiation.
Long-term effects of a parenting program for advanced cancer: A randomized controlled trial.
This randomized controlled trial evaluated a telephone-delivered, five-session parenting education program for parents with advanced, non-curable cancer who were raising children.
Syringomyelia secondary to degenerative spinal canal stenosis: a systematic review.
This PRISMA 2020 systematic review synthesised patient-level reports of syringomyelia associated with degenerative spinal canal stenosis, predominantly cervical spondylosis.
Efficacy of cognitive behavioral therapy for anxiety and depression symptoms in Parkinson's disease patients: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed cognitive behavioral therapy (CBT) for anxiety and depressive symptoms in adults with Parkinson’s disease (PD), pooling 21 randomized controlled trials involving 892…
Resistance training and protein supplementation in patients with incurable gastroesophageal cancer: a randomized feasibility trial.
This open-label, parallel-group randomized feasibility trial assessed resistance training plus protein supplementation during first-line chemotherapy in patients with incurable gastroesophageal cancer.
Erdheim-Chester disease: a diagnostic dilemma - a report of four cases.
Four adults aged 27–40 years presented with neurological Erdheim-Chester disease (ECD), with manifestations including cerebellar ataxia, dysarthria, tremor, visual deterioration, and headache.
Plozasiran for Severe Hypertriglyceridemia and Risk of Pancreatitis.
Two double-blind, placebo-controlled randomized trials evaluated plozasiran in 757 adults with severe hypertriglyceridemia.
A phase 2a, double-blind, randomised, placebo-controlled trial of the myeloperoxidase inhibitor, mitiperstat, in participants with COPD.
This phase 2a, double-blind, randomised, placebo-controlled trial assessed mitiperstat in adults aged 40–80 years with moderate-to-severe COPD, high exacerbation risk, and ongoing dual or triple inhaled therapy.
Combining quizartinib with intensive chemotherapy for older patients with newly diagnosed AML: results of the UK NCRI AML18 trial.
The multicentre randomised UK NCRI AML18 trial evaluated quizartinib after intensive chemotherapy, with or without maintenance, in patients older than 60 years with newly diagnosed AML or high-risk myelodysplastic…
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