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2000 articles

November 202624

Clinical ResearchGastroenterology

Predictors and prognostic impact of spontaneous portal vein thrombosis recanalization in cirrhosis: An individual patient data meta-analysis.

This individual patient data meta-analysis pooled cohort studies of patients with cirrhosis and portal vein thrombosis (PVT) who were not receiving anticoagulation.

Hepatol CommunNov 11, 2026Read summary
Clinical ResearchPediatrics

Physical Activity in Young Girls With Functional Abdominal Pain Disorders: Findings of a Randomized Controlled Intervention Trial With Dance and Yoga.

This randomized controlled trial assessed daily physical activity and abdominal pain in girls aged 9 to 13 years with functional abdominal pain disorders who participated in an 8-month dance and yoga intervention.

Clin J PainNov 11, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Postoperative Tumor-Informed Circulating Tumor DNA Status for Molecular Residual Disease Detection After Curative-Intent Resection of Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled observational evidence on postoperative tumor-informed circulating tumor DNA (ctDNA) as a marker of molecular residual disease after curative-intent resection of…

J Gastrointest CancerNov 11, 2026Read summary
Clinical ResearchUrologyOpen access

Effect of pelvic floor reconstruction on postoperative urinary continence after robot-assisted radical prostatectomy: a meta-analysis.

This meta-analysis pooled controlled studies comparing pelvic floor reconstruction (PR) with no reconstruction during robot-assisted radical prostatectomy (RARP).

J Robot SurgNov 10, 2026Read summary
Clinical ResearchHematologyOpen access

Efficacy and safety of apixaban versus rivaroxaban in acute venous thromboembolism: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis compared apixaban with rivaroxaban for acute venous thromboembolism in adults.

Eur J Clin PharmacolNov 10, 2026Read summary
Clinical ResearchPulmonologyOpen access

Effect of orofacial myofunctional therapy with auto-monitoring on the apnea-hypopnea index in patients with mild-to-moderate obstructive sleep apnea: a multicenter randomized controlled trial.

This multicenter randomized controlled trial assessed standardized orofacial myofunctional therapy (OMT) in treatment-naive adults with mild-to-moderate obstructive sleep apnea.

J Clin Sleep MedNov 10, 2026Read summary
Case ReportCardiothoracic SurgeryOpen access

Cannula exchange for refractory cannula infections during Berlin Heart EXCOR support: a case report.

A 4-year-old girl with truncus arteriosus and severe heart failure received Berlin Heart EXCOR (BHE) support after complex cardiac surgery.

J Artif OrgansNov 10, 2026Read case
Clinical ResearchAnesthesiology

Oliceridine vs Sufentanil Combined With Ondansetron for Postoperative Nausea and Vomiting and QTc Interval in Hysteroscopic Surgery: A Prospective Randomized Controlled Study.

This prospective, randomized, double-blind controlled study compared oliceridine plus ondansetron with sufentanil plus ondansetron in 62 patients undergoing non-intubated hysteroscopic surgery under general anesthesia.

Med Sci MonitNov 10, 2026Read summary
Clinical ResearchCardiologyOpen access

Cardiovascular outcomes of glucagon-like peptide-1 receptor agonists: A systematic review.

This systematic review evaluated 12 cardiovascular outcome-based randomised controlled trials of GLP-1 receptor agonists (GLP1RAs): 10 in people with type 2 diabetes (T2D), one in people with overweight or obesity and…

Am J Health Syst PharmNov 10, 2026Read summary
Clinical ResearchCardiology

Micro-axial flow pump vs veno-arterial extracorporeal membrane oxygenation for high-risk percutaneous coronary interventions: a randomized trial.

This prospective, multicentre, randomised, open-label non-inferiority trial compared prophylactic SynFlow 3.0 micro-axial flow pump support with VA-ECMO during non-emergent high-risk PCI in patients with complex…

Eur Heart JNov 10, 2026Read summary
Clinical ResearchGeneral Surgery

Efficacy of De-Epithelialized vs. Subepithelial Grafts in Periodontal Plastic Surgery for Gingival Recession: A Systematic Review and Meta-Analysis of Root Coverage Techniques.

This systematic review and meta-analysis compared de-epithelialized gingival grafts (DGG) with subepithelial connective tissue grafts (SCTG) for RT1 gingival recessions.

Clin Exp Dent ResNov 10, 2026Read summary
Clinical ResearchCardiology

Outcomes in the BETAMI-DANBLOCK trial compared with a Norwegian nationwide myocardial infarction population.

This transportability analysis compared participants in the BETAMI and DANBLOCK randomized trials with revascularized Norwegian patients who had myocardial infarction, LVEF ≥40%, and no heart failure.

Eur Heart JNov 10, 2026Read summary
Clinical ResearchPulmonology

Brain MRI changes following continuous positive airway pressure therapy in adults with obstructive sleep apnea: a systematic review.

This systematic review synthesized longitudinal brain MRI studies in adults with obstructive sleep apnea (OSA) before and after continuous positive airway pressure (CPAP), including comparisons with control groups.

SleepNov 10, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Impact of early versus delayed mobilization after arthroscopic rotator cuff repair in small and medium-sized tears: a prospective randomized study.

This prospective randomized study compared early with delayed mobilization after arthroscopic single-row knotless repair of small and medium full-thickness supraspinatus tears in 70 patients aged 20–70 years.

J Orthop Surg ResNov 10, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Dirozalkib versus Crizotinib in Advanced Anaplastic Lymphoma Kinase Inhibitor-Naïve ALK -Positive Non-Small-Cell Lung Cancer: A Multicenter, Randomized Phase III Trial.

DIAMOND-2 was a multicenter, randomized, open-label phase III trial comparing dirozalkib with crizotinib in adults with ALK inhibitor-naïve, ALK-positive advanced non-small-cell lung cancer.

Cancer Commun (Lond)Nov 10, 2026Read summary
Clinical ResearchOncology (Medical)Open access

The effect of listening to Qur'an on quality of life and sleep quality in breast cancer patients undergoing chemotherapy: a randomized controlled trial.

This open-label, participant-level randomized controlled trial with blinded statistical analysis examined whether listening to Qur’an during chemotherapy affected patient-reported quality of life and sleep in women with…

Med OncolNov 10, 2026Read summary
Clinical ResearchPsychiatry

Testing the Impact of the #Chatsafe Intervention on Young People's Ability to Communicate Safely About Suicide on Social Media: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether #chatsafe social media content improved safe online communication about suicide among young people aged 16–25 years.

Suicide Life Threat BehavNov 10, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Non-invasive vascular assessment in gestational hypertension and preeclampsia during pregnancy and the postpartum period: a systematic review.

This systematic review evaluated non-invasive measures of vascular structure and function in women with gestational hypertension or preeclampsia during pregnancy and postpartum.

Hypertens PregnancyNov 10, 2026Read summary
Clinical ResearchNeurologyOpen access

Slow-wave sleep mediates the compensatory effects of acute moderate-intensity exercise on declarative memory deficits in sleep restriction.

This randomized controlled trial tested whether one session of moderate-intensity exercise could protect declarative memory during sleep restriction and whether slow-wave sleep (SWS) mediated any benefit.

SleepNov 10, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Commonly experienced acute and cumulative 8-hour sleep loss differentially affect simulated driving during a night-time to early-morning commute: a randomized controlled crossover trial.

This randomized within-subject crossover trial compared simulated driving after normal sleep, four nights with 2 h less sleep per night, and one night without sleep in 20 healthy men.

SleepNov 10, 2026Read summary
Clinical ResearchGastroenterology

Time-dependent efficacy of seven pharmacological regimens for ulcer healing and delayed bleeding prevention after gastric endoscopic submucosal dissection: A frequentist network meta-analysis.

This frequentist network meta-analysis compared seven pharmacological regimens for ulcer healing and prevention of delayed bleeding or perforation after gastric endoscopic submucosal dissection.

PLoS OneNov 10, 2026Read summary
Clinical ResearchNeurologyOpen access

Loberamisal for Acute Ischemic Stroke: The LAIS Randomized Clinical Trial.

The LAIS trial was a multicenter, double-blind, randomized, placebo-controlled phase 3 study at 32 hospitals in China. It enrolled adults aged 18 to 80 years with acute ischemic stroke, treated within 48 hours, and…

JAMANov 10, 2026Read summary
Case ReportRheumatologyOpen access

Rheumatoid factor positivity in ANCA-negative eosinophilic granulomatosis with polyangiitis: cardiac mimicry, mononeuritis multiplex, and long-term outcome in a case-based systematic review.

A 42-year-old woman with long-standing asthma and rheumatoid factor (RF) of 322 IU/mL presented with myocardial infarction-like cardiac involvement despite non-obstructive coronary arteries.

Rheumatol IntNov 10, 2026Read case
Clinical ResearchCardiology

A nurse-coordinated intervention programme vs standard of care after an acute coronary syndrome: the ALLEPRE trial.

The multicentre, pragmatic, randomized ALLEPRE trial compared a nurse-coordinated prevention programme with hospital standard care in patients recovering from acute coronary syndrome.

Eur Heart JNov 10, 2026Read summary

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